Melatonin Ameliorates Inflammation and Oxidative Stress by Suppressing the p38MAPK Signaling Pathway in LPS-Induced Sheep Orchitis

Monophosphoryl lipid A alleviated radiation‐induced testicular injury through TLR4‐dependent exosomes

(2020) Zhe Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies

(2020) Keisaku Sato et al.   JOURNAL OF PINEAL RESEARCH

Protective effect of Alpha‐Linolenic acid on Lipopolysaccharide‐Induced Orchitis in mice

(2020) Fesih Ok et al.   ANDROLOGIA

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

(2020) Abhigyan Choudhury et al.   JOURNAL OF MEDICAL VIROLOGY

Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19

(2020) Russel J. Reiter et al.   Frontiers in Medicine

Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod

(2019) M.E. Matzkin et al.   EXPERIMENTAL GERONTOLOGY

Melatonin Regulates the Synthesis of Steroid Hormones on Male Reproduction: A Review

(2018) Kun Yu et al.   MOLECULES

Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells

(2018) Shou-Long Deng et al.   THERIOGENOLOGY

β-Adrenoceptors Trigger Melatonin Synthesis in Phagocytes

(2018) Marco Pires-Lapa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Viral threat to male fertility

(2018) Weihua Liu et al.   ANDROLOGIA

Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen

(2017) Shou-Long Deng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Local Actions of Melatonin in Somatic Cells of the Testis

(2017) Mónica Frungieri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Developmental origin and maintenance of distinct testicular macrophage populations

(2017) Noushin Mossadegh-Keller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex

(2017) So Yeon Kim et al.   Nature Communications

TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

(2017) Jingzhu Lv et al.   BMC Pulmonary Medicine

Melatonin prevents secondary intra-abdominal hypertension in rats possibly through inhibition of the p38 MAPK pathway

(2016) Mingtao Chang et al.   FREE RADICAL BIOLOGY AND MEDICINE

13-Methylberberine reduces HMGB1 release in LPS-activated RAW264.7 cells and increases the survival of septic mice through AMPK/P38 MAPK activation

(2016) Ki Churl Chang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Melatonin promotes development of haploid germ cells from early developing spermatogenic cells ofSuffolksheep under in vitro condition

(2016) Shou-Long Deng et al.   JOURNAL OF PINEAL RESEARCH

Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1)

(2015) Vaibhav Sidarala et al.   BIOCHEMICAL PHARMACOLOGY

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Differential Activation of Inflammatory Pathways in Testicular Macrophages Provides a Rationale for Their Subdued Inflammatory Capacity

(2015) Sudhanshu Bhushan et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 4 Promotes NO Synthesis by Upregulating GCHI Expression under Oxidative Stress Conditions in Sheep Monocytes/Macrophages

(2015) Shoulong Deng et al.   Oxidative Medicine and Cellular Longevity

Functional Status of Testicular Macrophages in an Immunopriviledged Niche in Cadmium Intoxicated Murine Testes

(2014) Sumana Chakraborty et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis

(2014) Ferial Aslani et al.   HUMAN REPRODUCTION

The anti-inflammatory potential of Cortex Phellodendron in vivo and in vitro: Down-regulation of NO and iNOS through suppression of NF-κB and MAPK activation

(2014) You Yeon Choi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Alterations in the time course of expression of the Nox family in the brain in a rat experimental cerebral ischemia and reperfusion model: effects of melatonin

(2014) Haiying Li et al.   JOURNAL OF PINEAL RESEARCH

Melatonin in testes of infertile men: evidence for anti-proliferative and anti-oxidant effects on local macrophage and mast cell populations

(2014) S. P. Rossi et al.   Andrology

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Melatonin modulates microsomal PGE synthase 1 and NF-E2-related factor-2-regulated antioxidant enzyme expression in LPS-induced murine peritoneal macrophages

(2013) M Aparicio-Soto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Melatonin suppresses nitric oxide production in glial cultures by pro-inflammatory cytokines through p38 MAPK inhibition

(2013) A. Vilar et al.   FREE RADICAL RESEARCH

Immune-Pineal Axis: Nuclear Factor κB (NF-kB) Mediates the Shift in the Melatonin Source from Pinealocytes to Immune Competent Cells

(2013) Regina Markus et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin ameliorates vascular endothelial dysfunction, inflammation, and atherosclerosis by suppressing the TLR4/NF-κB system in high-fat-fed rabbits

(2013) Ze-Ping Hu et al.   JOURNAL OF PINEAL RESEARCH

The role of melatonin in the cells of the innate immunity: a review

(2013) Juan R. Calvo et al.   JOURNAL OF PINEAL RESEARCH

Phenotypic and functional heterogeneity of the testicular macrophage population: a new regulatory model

(2013) Wendy R. Winnall et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Ethyl Pyruvate Induces Heme Oxygenase-1 Through p38 Mitogen-Activated Protein Kinase Activation by Depletion of Glutathione in RAW 264.7 Cells and Improves Survival in Septic Animals

(2012) Hwa Jin Jang et al.   ANTIOXIDANTS & REDOX SIGNALING

Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells

(2012) Mi-Zhen Xia et al.   JOURNAL OF PINEAL RESEARCH

Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling

(2012) Dingbo Shi et al.   JOURNAL OF PINEAL RESEARCH

A review of the molecular aspects of melatonin’s anti-inflammatory actions: recent insights and new perspectives

(2012) José L. Mauriz et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion

(2012) Jung-Woo Kang et al.   JOURNAL OF PINEAL RESEARCH

Changes in the Relative Inflammatory Responses in Sheep Cells Overexpressing of Toll-Like Receptor 4 When Stimulated with LPS

(2012) Shoulong Deng et al.   PLoS One

Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin-10 in vitro

(2011) W. R. Winnall et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Uropathogenic E. coli Induce Different Immune Response in Testicular and Peritoneal Macrophages: Implications for Testicular Immune Privilege

(2011) Sudhanshu Bhushan et al.   PLoS One

Paracrine role of testicular macrophages in control of Leydig cell activities in the wall lizard, Hemidactylus flaviviridis

(2007) Uniza W. Khan et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY