Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling

Puerarin inhibits iNOS, COX-2 and CRP expression via suppression of NF-κB activation in LPS-induced RAW264.7 macrophage cells

(2014) Wenzhi Hu et al.   Pharmacological Reports

Involvement of Cox-2 in the metastatic potential of chemotherapy-resistant breast cancer cells

(2011) Ju-Hee Kang et al.   BMC CANCER

Melatonin and Associated Signaling Pathways that Control Normal Breast Epithelium and Breast Cancer

(2011) Steven M. Hill et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Melatonin levels, determined by LC-ESI-MS/MS, fluctuate during the day/night cycle in Vitis vinifera cv Malbec: evidence of its antioxidant role in fruits

(2011) Hernán E. Boccalandro et al.   JOURNAL OF PINEAL RESEARCH

Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males

(2011) Julio J. Ochoa et al.   JOURNAL OF PINEAL RESEARCH

Melatonin synthesized by T lymphocytes as a ligand of the retinoic acid-related orphan receptor

(2011) Patricia J. Lardone et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer

(2011) Shanchun Guo et al.   PLoS One

Quercetin Suppresses Cyclooxygenase-2 Expression and Angiogenesis through Inactivation of P300 Signaling

(2011) Xiangsheng Xiao et al.   PLoS One

COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

(2010) Sharon A Glynn et al.   BMC CANCER

Melatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats

(2010) Gulgun Tahan et al.   DIGESTIVE DISEASES AND SCIENCES

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

(2010) Julien Bricambert et al.   JOURNAL OF CLINICAL INVESTIGATION

Mice Lacking Both TNF and IL‐1 Receptors Exhibit Reduced Lung Inflammation and Delay in Onset of Death following Infection with a Highly Virulent H5N1 Virus

(2010) Lucy A. Perrone et al.   JOURNAL OF INFECTIOUS DISEASES

Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms

(2010) Debasri Mukherjee et al.   JOURNAL OF PINEAL RESEARCH

Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes

(2010) Huichao Sun et al.   LIFE SCIENCES

The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation

(2010) F Meylan et al.   Mucosal Immunology

NF-κB related abnormal hyper-expression of iNOS and NO correlates with the inflammation procedure in biliary atresia livers

(2010) Lei Huang et al.   PEDIATRIC SURGERY INTERNATIONAL

Melatonin: Action as antioxidant and potential applications in human disease and aging

(2010) Dominique Bonnefont-Rousselot et al.   TOXICOLOGY

Cigarette smoke extract induces COX-2 expression via a PKCα/c-Src/EGFR, PDGFR/PI3K/Akt/NF-κB pathway and p300 in tracheal smooth muscle cells

(2009) Chuen-Mao Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Melatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells

(2009) C Martínez-Campa et al.   BRITISH JOURNAL OF CANCER

Melatonin reduces cardiac inflammatory injury induced by acute exercise

(2009) C. Veneroso et al.   JOURNAL OF PINEAL RESEARCH

Reactive Oxygen Species- and Nitric Oxide-Mediated Lung Inflammation and Mitochondrial Dysfunction in Wild-Type and iNOS-Deficient Mice Exposed to Diesel Exhaust Particles

(2009) Hongwen Zhao et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Transcriptional regulation of iNOS and COX-2 by a novel compound from Curcuma comosa in lipopolysaccharide-induced microglial activation

(2009) Anusorn Thampithak et al.   NEUROSCIENCE LETTERS

Lucidone Inhibits iNOS and COX-2 Expression in LPS-Induced RAW 264.7 Murine Macrophage Cells via NF-κB and MAPKs Signaling Pathways

(2009) K. Senthil Kumar et al.   PLANTA MEDICA

IL-1 Induces IGF-Dependent Epithelial Proliferation in Prostate Development and Reactive Hyperplasia

(2009) T. J. Jerde et al.   Science Signaling

Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases

(2008) Rasmus Boye Kjellerup et al.   EXPERIMENTAL DERMATOLOGY

Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-α, and COX-2 expression in mouse macrophage RAW 264.7

(2008) Tomonori Nakamura et al.   Journal of Natural Medicines

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

(2008) Xin Liu et al.   NATURE