An immune-based biomarker signature is associated with mortality in COVID-19 patients
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An immune-based biomarker signature is associated with mortality in COVID-19 patients
Authors
Keywords
-
Journal
JCI Insight
Volume 6, Issue 1, Pages -
Publisher
American Society for Clinical Investigation
Online
2020-11-25
DOI
10.1172/jci.insight.144455
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- IL-33 and ST2 as predictors of disease severity in children with viral acute lower respiratory infection
- (2020) Carolina Augusta Arantes Portugal et al. CYTOKINE
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Moving towards a systems-based classification of innate immune-mediated diseases
- (2020) Sinisa Savic et al. Nature Reviews Rheumatology
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
- (2020) Evangelos J. Giamarellos-Bourboulis et al. Cell Host & Microbe
- Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis
- (2020) George Dimopoulos et al. Cell Host & Microbe
- Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
- (2020) Safiya Richardson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19
- (2020) Yang Yang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
- (2020) Tobias Herold et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Clinical and immunological features of severe and moderate coronavirus disease 2019
- (2020) Guang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients
- (2020) Peter D Burbelo et al. JOURNAL OF INFECTIOUS DISEASES
- Tocilizumab treatment in COVID-19: A single center experience
- (2020) Pan Luo et al. JOURNAL OF MEDICAL VIROLOGY
- Predictors of mortality in hospitalized COVID‐19 patients: A systematic review and meta‐analysis
- (2020) Wenjie Tian et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
- (2020) Maximilian Ackermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Facing Covid-19 in Italy — Ethics, Logistics, and Therapeutics on the Epidemic’s Front Line
- (2020) Lisa Rosenbaum NEW ENGLAND JOURNAL OF MEDICINE
- Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
- (2020) Chaomin Wu et al. JAMA Internal Medicine
- Severe COVID-19 is marked by a dysregulated myeloid cell compartment
- (2020) Jonas Schulte-Schrepping et al. CELL
- Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19
- (2020) Aymeric Silvin et al. CELL
- IL-15 immunotherapy is a viable strategy for COVID-19
- (2020) Hemanth Kumar Kandikattu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- IL-6–based mortality risk model for hospitalized patients with COVID-19
- (2020) Rocio Laguna-Goya et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Flow Cytometry Identifies Risk Factors and Dynamic Changes in Patients with COVID-19
- (2020) Daniele Moratto et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent
- (2020) Alessio Mazzoni et al. JOURNAL OF CLINICAL INVESTIGATION
- Longitudinal analyses reveal immunological misfiring in severe COVID-19
- (2020) Carolina Lucas et al. NATURE
- A single-cell atlas of the peripheral immune response in patients with severe COVID-19
- (2020) Aaron J. Wilk et al. NATURE MEDICINE
- Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
- (2020) Divij Mathew et al. SCIENCE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Prompt Predicting of Early Clinical Deterioration of Moderate-to-Severe COVID-19 Patients: Usefulness of a Combined Score Using IL-6 in a Preliminary Study
- (2020) Alessandra Vultaggio et al. Journal of Allergy and Clinical Immunology-In Practice
- Levels of the TNF-Related Cytokine LIGHT Increase in Hospitalized COVID-19 Patients with Cytokine Release Syndrome and ARDS
- (2020) David S. Perlin et al. mSphere
- Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
- (2020) Jeong Seok Lee et al. Science Immunology
- Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease
- (2020) Yan Zhao et al. JCI Insight
- Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis
- (2020) Jennifer G. Wilson et al. JCI Insight
- Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
- (2020) Panagiotis Skendros et al. JOURNAL OF CLINICAL INVESTIGATION
- Neutrophil calprotectin identifies severe pulmonary disease in COVID‐19
- (2020) Hui Shi et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung
- (2020) Lucas D. Faustino et al. NATURE IMMUNOLOGY
- An inflammatory cytokine signature predicts COVID-19 severity and survival
- (2020) Diane Marie Del Valle et al. NATURE MEDICINE
- A dynamic COVID-19 immune signature includes associations with poor prognosis
- (2020) Adam G. Laing et al. NATURE MEDICINE
- Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients
- (2020) Rami M. Elshazli et al. PLoS One
- Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
- (2020) Prabhu S. Arunachalam et al. SCIENCE
- Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
- (2020) Qian Zhang et al. SCIENCE
- Autoantibodies against type I IFNs in patients with life-threatening COVID-19
- (2020) Paul Bastard et al. SCIENCE
- Monocyte CD169 Expression as a Biomarker in the Early Diagnosis of Coronavirus Disease 2019
- (2020) Anne-Sophie Bedin et al. JOURNAL OF INFECTIOUS DISEASES
- Self-Awareness: Nucleic Acid–Driven Inflammation and the Type I Interferonopathies
- (2019) Carolina Uggenti et al. Annual Review of Immunology
- Immune regulation by glucocorticoids can be linked to cell type–dependent transcriptional responses
- (2019) Luis M. Franco et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The γc Family of Cytokines: Basic Biology to Therapeutic Ramifications
- (2019) Warren J. Leonard et al. IMMUNITY
- Severe influenza pneumonitis in children with inherited TLR3 deficiency
- (2019) Hye Kyung Lim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines
- (2019) Nicholas Hernandez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients
- (2019) Christelle Dubois et al. Scientific Reports
- Prediction of mortality in adult patients with sepsis using six biomarkers: a systematic review and meta-analysis
- (2019) Andreas Pregernig et al. Annals of Intensive Care
- Predictive value of low interleukin-33 in critically ill patients
- (2018) Konstantin A. Krychtiuk et al. CYTOKINE
- Development of a Validated Interferon Score Using NanoString Technology
- (2018) Hanna Kim et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
- (2018) Theodoros Giavridis et al. NATURE MEDICINE
- Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target
- (2018) Ewelina Piktel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency
- (2018) Nicholas Hernandez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
- (2017) Brad Griesenauer et al. Frontiers in Immunology
- Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
- (2016) Rudragouda Channappanavar et al. Cell Host & Microbe
- Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
- (2016) Bita Shakoory et al. CRITICAL CARE MEDICINE
- Diagnostic Accuracy of Lipopolysaccharide-Binding Protein as Biomarker for Sepsis in Adult Patients: A Systematic Review and Meta-Analysis
- (2016) Kuan-Fu Chen et al. PLoS One
- Increased IL-33 expression in chronic obstructive pulmonary disease
- (2015) Jie Xia et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Interleukin-15 is associated with disease severity in viral bronchiolitis
- (2015) T. Ronan Leahy et al. EUROPEAN RESPIRATORY JOURNAL
- Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency
- (2015) Jolan E. Walter et al. JOURNAL OF CLINICAL INVESTIGATION
- Soluble ST2 as a prognostic marker in community-acquired pneumonia
- (2015) Masato Watanabe et al. JOURNAL OF INFECTION
- Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency
- (2015) M. J. Ciancanelli et al. SCIENCE
- Human IFNAR2 deficiency: Lessons for antiviral immunity
- (2015) Christopher J. A. Duncan et al. Science Translational Medicine
- Viral Antigen Induces Differentiation of Foxp3+ Natural Regulatory T Cells in Influenza Virus-Infected Mice
- (2013) F. Bedoya et al. JOURNAL OF IMMUNOLOGY
- Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation
- (2011) Ashutosh Chaudhry et al. IMMUNITY
- Unknown
- (2011) Jochen Grommes et al. MOLECULAR MEDICINE
- IRF8Mutations and Human Dendritic-Cell Immunodeficiency
- (2011) Sophie Hambleton et al. NEW ENGLAND JOURNAL OF MEDICINE
- Soluble ST2 plasma concentrations predict mortality in severe sepsis
- (2010) Jacobien J. Hoogerwerf et al. INTENSIVE CARE MEDICINE
- Basic Concepts and Methods for Joint Models of Longitudinal and Survival Data
- (2010) Joseph G. Ibrahim et al. JOURNAL OF CLINICAL ONCOLOGY
- Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection
- (2010) Jose C Alves-Filho et al. NATURE MEDICINE
- Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells
- (2009) J. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started