Flavonolignan Conjugates as DNA-binding Ligands and Topoisomerase I Inhibitors: Electrochemical and Electrophoretic Approaches

Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity

(2016) Michaela Pyszková et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers

(2014) Eva Vavříková et al.   MOLECULES

Chemistry of silybin

(2014) D. Biedermann et al.   NATURAL PRODUCT REPORTS

eL-Chem Viewer: A Freeware Package for the Analysis of Electroanalytical Data and Their Post-Acquisition Processing

(2014) Jan Hrbac et al.   SENSORS

Enzymatic preparation of silybin phase II metabolites: sulfation using aryl sulfotransferase from rat liver

(2013) Kateřina Purchartová et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Antioxidant, metal-binding and DNA-damaging properties of flavonolignans: A joint experimental and computational highlight based on 7-O-galloylsilybin

(2013) Jan Vacek et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Biotransformation of Silybin and its Congeners

(2013) Vladimír Kren et al.   CURRENT DRUG METABOLISM

Effect of 3-O-Galloyl Substitution on the Electrochemical Oxidation of Quercetin and Silybin Galloyl Esters at Glassy Carbon Electrode

(2013) Martina Zatloukalová et al.   ELECTROANALYSIS

Electrochemical Behaviour of Alkaloids: Detection and Interaction with DNA and Proteins

(2013) Vilím Šimánek et al.   HETEROCYCLES

A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway

(2013) Jiří Vrba et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bioavailability of silymarin flavonolignans: drug formulations and biotransformation

(2013) Eleni Theodosiou et al.   PHYTOCHEMISTRY REVIEWS

A review on antioxidants, prooxidants and related controversy: Natural and synthetic compounds, screening and analysis methodologies and future perspectives

(2012) Márcio Carocho et al.   FOOD AND CHEMICAL TOXICOLOGY

Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis

(2011) Stéphane Quideau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical investigation of flavonolignans and study of their interactions with DNA in the presence of Cu(II)

(2011) Martina Zatloukalová et al.   BIOELECTROCHEMISTRY

New C-23 modified of silybin and 2,3-dehydrosilybin: Synthesis and preliminary evaluation of antioxidant properties

(2011) Armando Zarrelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory

(2011) Pavlína Košinová et al.   CHEMPHYSCHEM

Oxidation of Sanguinarine and Its Dihydro-Derivative at a Pyrolytic Graphite Electrode Using Ex Situ Voltammetry. Study of the Interactions of the Alkaloids with DNA

(2011) Jan Vacek et al.   ELECTROANALYSIS

Phenol and para-substituted phenols electrochemical oxidation pathways

(2011) Teodor Adrian Enache et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Analytical methods and strategies in the study of plant polyphenolics in clinical samples

(2010) Jan Vacek et al.   Analytical Methods

Selective binding of tumor suppressor p53 protein to topologically constrained DNA: Modulation by intercalative drugs

(2010) Hana Pivoňková et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antioxidant and antiviral activities of silybin fatty acid conjugates

(2009) Radek Gažák et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2,3-Dehydrosilybin Is a Better DNA Topoisomerase I Inhibitor than Its Parental Silybin

(2008) Piyanut Thongphasuk et al.   CHEMOTHERAPY

Molecular mechanisms of silybin and 2,3-dehydrosilybin antiradical activity—role of individual hydroxyl groups

(2008) Radek Gažák et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanism of the Antioxidant Action of Silybin and 2,3-Dehydrosilybin Flavonolignans: A Joint Experimental and Theoretical Study

(2008) Patrick Trouillas et al.   JOURNAL OF PHYSICAL CHEMISTRY A