Systematic Review: Anesthetic Protocols and Management as Confounders in Rodent Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging (BOLD fMRI)—Part B: Effects of Anesthetic Agents, Doses and Timing

BOLD fMRI and hemodynamic responses to somatosensory stimulation in anesthetized mice: spontaneous breathing vs. mechanical ventilation

(2020) Hyun‐Ji Shim et al.   NMR IN BIOMEDICINE

fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing

(2020) Fuqiang Zhao et al.   NEUROIMAGE

The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational Neuroimaging

(2020) Henning M. Reimann et al.   Frontiers in Systems Neuroscience

Systematic Review: Anaesthetic Protocols and Management as Confounders in Rodent Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging (BOLD fMRI)–Part A: Effects of Changes in Physiological Parameters

(2020) Aline R. Steiner et al.   Frontiers in Neuroscience

Characteristics of fMRI responses to visual stimulation in anesthetized vs. awake mice

(2020) Thi Ngoc Anh Dinh et al.   NEUROIMAGE

Temporal stability of fMRI in medetomidine-anesthetized rats

(2019) Nikoloz Sirmpilatze et al.   Scientific Reports

A Systematic Review and Meta‐analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department

(2018) Nicholas Karlow et al.   ACADEMIC EMERGENCY MEDICINE

Mouse fMRI under ketamine and xylazine anesthesia: Robust contralateral somatosensory cortex activation in response to forepaw stimulation

(2018) Hyun-Ji Shim et al.   NEUROIMAGE

Functional connectivity under six anesthesia protocols and the awake condition in rat brain

(2018) Jaakko Paasonen et al.   NEUROIMAGE

Physiological characterization of a robust survival rodent fMRI method

(2017) Julia K. Brynildsen et al.   MAGNETIC RESONANCE IMAGING

Altered regional connectivity reflecting effects of different anaesthesia protocols in the mouse brain

(2017) Tong Wu et al.   NEUROIMAGE

Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal

(2017) Yu-Rong Gao et al.   NEUROIMAGE

Dynamic reorganization of intrinsic functional networks in the mouse brain

(2017) Joanes Grandjean et al.   NEUROIMAGE

Severity classification of repeated isoflurane anesthesia in C57BL/6JRj mice—Assessing the degree of distress

(2017) Katharina Hohlbaum et al.   PLoS One

Resting State fMRI in Mice Reveals Anesthesia Specific Signatures of Brain Functional Networks and Their Interactions

(2017) Qasim Bukhari et al.   Frontiers in Neural Circuits

Water diffusion closely reveals neural activity status in rat brain loci affected by anesthesia

(2017) Yoshifumi Abe et al.   PLOS BIOLOGY

Resting state functional network disruptions in a kainic acid model of temporal lobe epilepsy

(2017) Ravnoor Singh Gill et al.   NeuroImage-Clinical

Maintenance and Representation of Mind Wandering during Resting-State fMRI

(2017) Ying-hui Chou et al.   Scientific Reports

Interhemispheric resting-state functional connectivity of the claustrum in the awake and anesthetized states

(2016) Jared B. Smith et al.   Brain Structure & Function

Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat

(2016) Jaakko Paasonen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Contributions of structural connectivity and cerebrovascular parameters to functional magnetic resonance imaging signals in mice at rest and during sensory paw stimulation

(2016) Aileen Schroeter et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Novel method for functional brain imaging in awake minimally restrained rats

(2016) Pei-Ching Chang et al.   JOURNAL OF NEUROPHYSIOLOGY

Physiological effects of a habituation procedure for functional MRI in awake mice using a cryogenic radiofrequency probe

(2016) Keitaro Yoshida et al.   JOURNAL OF NEUROSCIENCE METHODS

Resting-state functional MRI as a tool for evaluating brain hemodynamic responsiveness to external stimuli in rats

(2016) Jaakko Paasonen et al.   MAGNETIC RESONANCE IN MEDICINE

Propofol anesthesia reduces Lempel-Ziv complexity of spontaneous brain activity in rats

(2016) Anthony G. Hudetz et al.   NEUROSCIENCE LETTERS

Global Functional Connectivity Differences between Sleep-Like States in Urethane Anesthetized Rats Measured by fMRI

(2016) Ekaterina Zhurakovskaya et al.   PLoS One

Distinct effects of isoflurane on basal BOLD signals in tissue/vascular microstructures in rats

(2016) Tomokazu Tsurugizawa et al.   Scientific Reports

Rat aversion to sevoflurane and isoflurane

(2015) Julie Boulanger Bertolus et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Cholinergic and serotonergic modulations differentially affect large-scale functional networks in the mouse brain

(2015) Disha Shah et al.   Brain Structure & Function

The hemodynamic response to somatosensory stimulation in mice depends on the anesthetic used: Implications on analysis of mouse fMRI data

(2015) Felix Schlegel et al.   NEUROIMAGE

Mapping the functional network of medial prefrontal cortex by combining optogenetics and fMRI in awake rats

(2015) Zhifeng Liang et al.   NEUROIMAGE

Dynamic resting state functional connectivity in awake and anesthetized rodents

(2015) Zhifeng Liang et al.   NEUROIMAGE

Gradual emergence of spontaneous correlated brain activity during fading of general anesthesia in rats: Evidences from fMRI and local field potentials

(2015) Ruggero G. Bettinardi et al.   NEUROIMAGE

Stress-induced alterations in large-scale functional networks of the rodent brain

(2015) Marloes J.A.G. Henckens et al.   NEUROIMAGE

A systematic review of physiological methods in rodent pharmacological MRI studies

(2015) Jennifer X. Haensel et al.   PSYCHOPHARMACOLOGY

Considerations for resting state functional MRI and functional connectivity studies in rodents

(2015) Wen-Ju Pan et al.   Frontiers in Neuroscience

The power of using functional fMRI on small rodents to study brain pharmacology and disease

(2015) Elisabeth Jonckers et al.   Frontiers in Pharmacology

Mouse aversion to isoflurane versus carbon dioxide gas

(2014) Carly M. Moody et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Influence of repeated anaesthesia on physiological parameters in male Wistar rats: a telemetric study about isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl

(2014) Maike Albrecht et al.   BMC Veterinary Research

Neurovascular Coupling and Decoupling in the Cortex during Voluntary Locomotion

(2014) B.-X. Huo et al.   JOURNAL OF NEUROSCIENCE

Robust deep brain stimulation functional MRI procedures in rats and mice using an MR-compatible tungsten microwire electrode

(2014) Hsin-Yi Lai et al.   MAGNETIC RESONANCE IN MEDICINE

Neuroplasticity to a single-episode traumatic stress revealed by resting-state fMRI in awake rats

(2014) Zhifeng Liang et al.   NEUROIMAGE

Optimization of anesthesia protocol for resting-state fMRI in mice based on differential effects of anesthetics on functional connectivity patterns

(2014) Joanes Grandjean et al.   NEUROIMAGE

Differentiating BOLD and non-BOLD signals in fMRI time series from anesthetized rats using multi-echo EPI at 11.7T

(2014) Prantik Kundu et al.   NEUROIMAGE

Pharmacological insight into neurotransmission origins of resting-state functional connectivity: α2-adrenergic agonist vs antagonist

(2014) Fatima A. Nasrallah et al.   NEUROIMAGE

Fine-grained mapping of mouse brain functional connectivity with resting-state fMRI

(2014) Anna E. Mechling et al.   NEUROIMAGE

Specificity of stimulus-evoked fMRI responses in the mouse: The influence of systemic physiological changes associated with innocuous stimulation under four different anesthetics

(2014) Aileen Schroeter et al.   NEUROIMAGE

Brain-state dependent uncoupling of BOLD and local field potentials in laminar olfactory bulb

(2014) Ling Gong et al.   NEUROSCIENCE LETTERS

Time-dependent effects of isoflurane and dexmedetomidine on functional connectivity, spectral characteristics, and spatial distribution of spontaneous BOLD fluctuations

(2014) Matthew Evan Magnuson et al.   NMR IN BIOMEDICINE

Repeated BOLD-fMRI Imaging of Deep Brain Stimulation Responses in Rats

(2014) Tzu-Hao Harry Chao et al.   PLoS One

Contributions and complexities from the use of in vivo animal models to improve understanding of human neuroimaging signals

(2014) Chris Martin   Frontiers in Neuroscience

A comparison of medetomidine and its active enantiomer dexmedetomidine when administered with ketamine in mice

(2013) Wesley M Burnside et al.   BMC Veterinary Research

Anesthesia differentially modulates spontaneous network dynamics by cortical area and layer

(2013) Kristin K. Sellers et al.   JOURNAL OF NEUROPHYSIOLOGY

Different anesthesia regimes modulate the functional connectivity outcome in mice

(2013) Elisabeth Jonckers et al.   MAGNETIC RESONANCE IN MEDICINE

Mapping thalamocortical networks in rat brain using resting-state functional connectivity

(2013) Zhifeng Liang et al.   NEUROIMAGE

Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol

(2013) Xiping Liu et al.   NEUROIMAGE

Detection of functional connectivity in the resting mouse brain

(2013) Fatima A. Nasrallah et al.   NEUROIMAGE

Neural correlate of resting-state functional connectivity under α2 adrenergic receptor agonist, medetomidine

(2013) Fatima A Nasrallah et al.   NEUROIMAGE

Sub-Anesthetic Ketamine Modulates Intrinsic BOLD Connectivity Within the Hippocampal-Prefrontal Circuit in the Rat

(2013) Natalia Gass et al.   NEUROPSYCHOPHARMACOLOGY

Reliability and spatial specificity of rat brain sensorimotor functional connectivity networks are superior under sedation compared with general anesthesia

(2013) Daniel Kalthoff et al.   NMR IN BIOMEDICINE

Rat aversion to isoflurane versus carbon dioxide

(2012) D. Wong et al.   Biology Letters

The Change of Functional Connectivity Specificity in Rats Under Various Anesthesia Levels and its Neural Origin

(2012) Xiao Liu et al.   BRAIN TOPOGRAPHY

Simultaneous BOLD fMRI and local field potential measurements during kainic acid-induced seizures

(2012) Antti M. Airaksinen et al.   EPILEPSIA

Effects of the α2-adrenergic receptor agonist dexmedetomidine on neural, vascular and BOLD fMRI responses in the somatosensory cortex

(2012) Mitsuhiro Fukuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Biophysical and Physiological Origins of Blood Oxygenation Level-Dependent fMRI Signals

(2012) Seong-Gi Kim et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intrinsic Organization of the Anesthetized Brain

(2012) Z. Liang et al.   JOURNAL OF NEUROSCIENCE

Differential effect of isoflurane, medetomidine, and urethane on BOLD responses to acute levo-tetrahydropalmatine in the rat

(2011) Xiping Liu et al.   MAGNETIC RESONANCE IN MEDICINE

Fractal analysis of spontaneous fluctuations of the BOLD signal in rat brain

(2011) Peter Herman et al.   NEUROIMAGE

Pharmacological modulation of functional connectivity: α2-adrenergic receptor agonist alters synchrony but not neural activation

(2011) Fatima A. Nasrallah et al.   NEUROIMAGE

Anticorrelated resting-state functional connectivity in awake rat brain

(2011) Zhifeng Liang et al.   NEUROIMAGE

Role of Astrocytes in Neurovascular Coupling

(2011) Gabor C. Petzold et al.   NEURON

State-dependent functional connectivity of rat olfactory system assessed by fMRI

(2011) D.A. Wilson et al.   NEUROSCIENCE LETTERS

Altered Thalamocortical Functional Connectivity by Propofol Anesthesia in Rats

(2011) Ye Tu et al.   PHARMACOLOGY

Neural Origin of Spontaneous Hemodynamic Fluctuations in Rats under Burst-Suppression Anesthesia Condition

(2010) X. Liu et al.   CEREBRAL CORTEX

Functional Networks in the Anesthetized Rat Brain Revealed by Independent Component Analysis of Resting-State fMRI

(2010) R. Matthew Hutchison et al.   JOURNAL OF NEUROPHYSIOLOGY

Mapping brain networks in awake mice using combined optical neural control and fMRI

(2010) M. Desai et al.   JOURNAL OF NEUROPHYSIOLOGY

On the use of α-chloralose for repeated BOLD fMRI measurements in rats

(2010) Benito de Celis Alonso et al.   JOURNAL OF NEUROSCIENCE METHODS

Comparison of α-chloralose, medetomidine and isoflurane anesthesia for functional connectivity mapping in the rat

(2010) Kathleen A. Williams et al.   MAGNETIC RESONANCE IMAGING

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Frequency-dependent neural activity, CBF, and BOLD fMRI to somatosensory stimuli in isoflurane-anesthetized rats

(2010) Tae Kim et al.   NEUROIMAGE

High field BOLD response to forepaw stimulation in the mouse

(2010) Joanna M. Adamczak et al.   NEUROIMAGE

Temporal scaling properties and spatial synchronization of spontaneous blood oxygenation level-dependent (BOLD) signal fluctuations in rat sensorimotor network at different levels of isoflurane anesthesia

(2010) Kun Wang et al.   NMR IN BIOMEDICINE

Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep

(2009) E. HUUPPONEN et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Increasing the Duration of Isoflurane Anesthesia Decreases the Minimum Alveolar Anesthetic Concentration in 7-Day-Old but Not in 60-Day-Old Rats

(2009) Greg Stratmann et al.   ANESTHESIA AND ANALGESIA

Dose-dependent effect of isoflurane on neurovascular coupling in rat cerebral cortex

(2009) Kazuto Masamoto et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A New Scenario for Negative Functional Magnetic Resonance Imaging Signals: Endogenous Neurotransmission

(2009) Y.-Y. I. Shih et al.   JOURNAL OF NEUROSCIENCE

A protocol for use of medetomidine anesthesia in rats for extended studies using task-induced BOLD contrast and resting-state functional connectivity

(2009) Christopher P. Pawela et al.   NEUROIMAGE

Effects of isoflurane and alpha-chloralose anesthesia on BOLD fMRI responses to ingested l-glutamate in rats

(2009) T. Tsurugizawa et al.   NEUROSCIENCE

ANTINOCICEPTIVE EFFECT OF MORPHINE IN α-CHLORALOSE AND ISOFLURANE ANESTHETIZED RATS USING BOLD fMRI

(2008) Chin-Mei Chen et al.   Biomedical Engineering - Applications, Basis and Communications

Isoflurane anesthesia is a valuable alternative forα-chloralose anesthesia in the forepaw stimulation model in rats

(2008) Mathieu G Sommers et al.   NMR IN BIOMEDICINE

Consciousness and Anesthesia

(2008) M. T. Alkire et al.   SCIENCE

Spatio-temporal characteristics of low-frequency BOLD signal fluctuations in isoflurane-anesthetized rat brain

(2007) Sridhar S. Kannurpatti et al.   NEUROIMAGE