Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-13
DOI
10.3389/fonc.2020.600715
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Erythrocyte Ascorbate Is a Potential Indicator of Steady-State Plasma Ascorbate Concentrations in Healthy Non-Fasting Individuals
- (2020) Juliet M. Pullar et al. Nutrients
- Vitamin C as a Modulator of the Response to Cancer Therapy
- (2019) Wiktoria Blaszczak et al. MOLECULES
- Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels
- (2019) Elizabeth J. Campbell et al. BMC CANCER
- Phase I study of high-dose ascorbic acid with mFOLFOX6 or FOLFIRI in patients with metastatic colorectal cancer or gastric cancer
- (2019) Feng Wang et al. BMC CANCER
- Reprogramming the Epigenome With Vitamin C
- (2019) Taylor Lee Chong et al. Frontiers in Cell and Developmental Biology
- First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma
- (2019) Bryan G. Allen et al. CLINICAL CANCER RESEARCH
- Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1
- (2019) Andrew B. Das et al. Blood Cancer Journal
- The Pharmacokinetics of Vitamin C
- (2019) Jens Lykkesfeldt et al. Nutrients
- Pharmacologic ascorbate (P-AscH−) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma
- (2018) Justin G. Wilkes et al. CLINICAL & EXPERIMENTAL METASTASIS
- Vitamin C deficiency in Australian hospitalized patients: an observational study
- (2018) Yogesh Sharma et al. INTERNAL MEDICINE JOURNAL
- Vitamin C in Stem Cell Reprogramming and Cancer
- (2018) Luisa Cimmino et al. TRENDS IN CELL BIOLOGY
- Potential Mechanisms of Action for Vitamin C in Cancer: Reviewing the Evidence
- (2018) Margreet C. M. Vissers et al. Frontiers in Physiology
- Pharmacological ascorbate reduces radiation-induced normal tissue toxicity and enhances tumor radiosensitization in pancreatic cancer
- (2018) Matthew S Alexander et al. CANCER RESEARCH
- Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio-Chemotherapy While Protecting Normal Tissue
- (2018) Joshua D. Schoenfeld et al. SEMINARS IN RADIATION ONCOLOGY
- The Association Between Ascorbate and the Hypoxia-Inducible Factors in Human Renal Cell Carcinoma Requires a Functional Von Hippel-Lindau Protein
- (2018) Christina Wohlrab et al. Frontiers in Oncology
- Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis
- (2017) Enlong Ma et al. FREE RADICAL BIOLOGY AND MEDICINE
- Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study
- (2017) John Pearson et al. Nutrients
- High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study
- (2017) Kishore Polireddy et al. Scientific Reports
- The epigenetic role of vitamin C in health and disease
- (2016) Vladimir Camarena et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
- (2016) Gregg L Semenza EMBO JOURNAL
- Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice
- (2016) Elizabeth J. Campbell et al. FREE RADICAL BIOLOGY AND MEDICINE
- Oxalate Nephropathy After Continuous Infusion of High-Dose Vitamin C as an Adjunct to Burn Resuscitation
- (2016) Michelle Buehner et al. Journal of Burn Care & Research
- Nutritional Aspects of Gastrointestinal Wound Healing
- (2016) Kaushik Mukherjee et al. Advances in Wound Care
- Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
- (2015) J. Du et al. CANCER RESEARCH
- Effect of Glucose on GLUT1-Dependent Intracellular Ascorbate Accumulation and Viability of Thyroid Cancer Cells
- (2015) Paweł Jóźwiak et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
- (2015) J. Yun et al. SCIENCE
- Human erythrocytes transport dehydroascorbic acid and sugars using the same transporter complex
- (2014) Jay M. Sage et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Elimination of Ascorbic Acid After High-Dose Infusion in Prostate Cancer Patients: A Pharmacokinetic Evaluation
- (2014) Torben K. Nielsen et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Pharmacokinetic modeling of ascorbate diffusion through normal and tumor tissue
- (2014) Caroline Kuiper et al. FREE RADICAL BIOLOGY AND MEDICINE
- High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy
- (2014) Y. Ma et al. Science Translational Medicine
- The Effect of Intravenous Vitamin C on Cancer- and Chemotherapy-Related Fatigue and Quality of Life
- (2014) Anitra C. Carr et al. Frontiers in Oncology
- Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer
- (2014) Caroline Kuiper et al. Frontiers in Oncology
- Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
- (2013) J. L. Welsh et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer
- (2013) Christopher M. Stephenson et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in the NCI60 cancer cell lines
- (2013) Tobias Sinnberg et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Ascorbate antagonizes nickel ion to regulate JMJD1A expression in kidney cancer cells
- (2012) X. Guo et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Low Ascorbate Levels Are Associated with Increased Hypoxia-Inducible Factor-1 Activity and an Aggressive Tumor Phenotype in Endometrial Cancer
- (2010) C. Kuiper et al. CANCER RESEARCH
- Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects
- (2010) Sebastian J. Padayatty et al. PLoS One
- Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
- (2008) L. J. Hoffer et al. ANNALS OF ONCOLOGY
- Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
- (2008) Q. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started