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Title
The epigenetic role of vitamin C in health and disease
Authors
Keywords
Epigenetics, Vitamin C, Methylcytosine dioxygenase, DNA methylation, JmjC domain-containing histone demethylases, Histone methylation, Scurvy
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 8, Pages 1645-1658
Publisher
Springer Nature
Online
2016-02-04
DOI
10.1007/s00018-016-2145-x
References
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Related references
Note: Only part of the references are listed.- Regulation of the Epigenome by Vitamin C
- (2015) Juan I. Young et al. Annual Review of Nutrition
- Vitamin C induces a pluripotent state in mouse embryonic stem cells by modulating microRNA expression
- (2015) Yuan Gao et al. FEBS Journal
- Function and information content of DNA methylation
- (2015) Dirk Schübeler NATURE
- Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease
- (2015) Tammaryn Lashley et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- How Schwann Cells Sort Axons
- (2015) M. Laura Feltri et al. NEUROSCIENTIST
- Lymphocyte vitamin C levels as potential biomarker for progression of Parkinson's disease
- (2015) Kazuki Ide et al. NUTRITION
- Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through TET1- and JMJD3-Dependent Epigenetic Control Manner
- (2015) Xi-Biao He et al. STEM CELLS
- Schwann Cell Myelination
- (2015) James L. Salzer Cold Spring Harbor Perspectives in Biology
- Epigenetic reprogramming of melanoma cells by vitamin C treatment
- (2015) Christopher B Gustafson et al. Clinical Epigenetics
- Genome-Wide Mapping of DNA Hydroxymethylation in Osteoarthritic Chondrocytes
- (2015) Sarah E. B. Taylor et al. Arthritis & Rheumatology
- Improved Development of Somatic Cell Cloned Mouse Embryos by Vitamin C and Latrunculin A
- (2015) Anna Mallol et al. PLoS One
- Histone Demethylation Maintains Prdm14 and Tsix Expression and Represses Xist in Embryonic Stem Cells
- (2015) Yasunao F. Kamikawa et al. PLoS One
- Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?
- (2014) Amy Reeve et al. AGEING RESEARCH REVIEWS
- Programming and Inheritance of Parental DNA Methylomes in Mammals
- (2014) Lu Wang et al. CELL
- Tet3 and DNA Replication Mediate Demethylation of Both the Maternal and Paternal Genomes in Mouse Zygotes
- (2014) Li Shen et al. Cell Stem Cell
- Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
- (2014) Fan Guo et al. Cell Stem Cell
- Vitamin C and survival among women with breast cancer: A Meta-analysis
- (2014) Holly R. Harris et al. EUROPEAN JOURNAL OF CANCER
- Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs
- (2014) Janne Gram Schjoldager et al. EUROPEAN JOURNAL OF NUTRITION
- Polymorphisms in sodium-dependent vitamin C transporter genes and plasma, aqueous humor and lens nucleus ascorbate concentrations in an ascorbate depleted setting
- (2014) Srinivasan Senthilkumari et al. EXPERIMENTAL EYE RESEARCH
- Differences in Vitamin E and C Profile Between Infant Formula and Human Milk and Relative Susceptibility to Lipid Oxidation
- (2014) Ingrid Elisia et al. INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
- The plasma level of retinol, vitamins A, C and α-tocopherol could reduce breast cancer risk? A meta-analysis and meta-regression
- (2014) Fulan Hu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- DNA methylation signatures link prenatal famine exposure to growth and metabolism
- (2014) Elmar W. Tobi et al. Nature Communications
- Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
- (2014) Paula Dominguez-Salas et al. Nature Communications
- Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation
- (2014) Julian R. Peat et al. Cell Reports
- Stage-Dependent and Locus-Specific Role of Histone Demethylase Jumonji D3 (JMJD3) in the Embryonic Stages of Lung Development
- (2014) Qingtian Li et al. PLoS Genetics
- The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases
- (2014) Sahar Al-Mahdawi et al. Frontiers in Neuroscience
- Does Vitamin C Deficiency Increase Lifestyle-Associated Vascular Disease Progression? Evidence Based on Experimental and Clinical Studies
- (2013) Pernille Tveden-Nyborg et al. ANTIOXIDANTS & REDOX SIGNALING
- Role of Vitamin C in the Function of the Vascular Endothelium
- (2013) James M. May et al. ANTIOXIDANTS & REDOX SIGNALING
- Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate
- (2013) Kevin M. Dickson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs
- (2013) Janne G. Schjoldager et al. BRITISH JOURNAL OF NUTRITION
- Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
- (2013) Li Shen et al. CELL
- Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming
- (2013) Chun-Xiao Song et al. CELL
- Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives
- (2013) Cornelia G. Spruijt et al. CELL
- Breathing-in epigenetic change with vitamin C
- (2013) Asun Monfort et al. EMBO REPORTS
- Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine
- (2013) Emily A. Minor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ascorbic Acid Enhances Tet-Mediated 5-Methylcytosine Oxidation and Promotes DNA Demethylation in Mammals
- (2013) Ruichuan Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Epigenetic changes in the progression of Alzheimer's disease
- (2013) M.A. Bradley-Whitman et al. MECHANISMS OF AGEING AND DEVELOPMENT
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
- (2013) Kathryn Blaschke et al. NATURE
- Vitamin C modulates TET1 function during somatic cell reprogramming
- (2013) Jiekai Chen et al. NATURE GENETICS
- Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
- (2013) Natacha Coppieters et al. NEUROBIOLOGY OF AGING
- Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice
- (2013) Yuki Kishimoto et al. PEDIATRIC RESEARCH
- Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes
- (2013) R. Lambrot et al. Nature Communications
- Nuclear Exclusion of TET1 Is Associated with Loss of 5-Hydroxymethylcytosine in IDH1 Wild-Type Gliomas
- (2012) Tim Müller et al. AMERICAN JOURNAL OF PATHOLOGY
- Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis
- (2012) Marlene Krämer et al. ANNALS OF THE RHEUMATIC DISEASES
- Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma
- (2012) Christine Guo Lian et al. CELL
- MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System
- (2012) Marian Mellén et al. CELL
- Tet family proteins and 5-hydroxymethylcytosine in development and disease
- (2012) L. Tan et al. DEVELOPMENT
- Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
- (2012) Claudia A. Doege et al. NATURE
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
- (2012) Jiekai Chen et al. NATURE GENETICS
- Interventions with Vitamins B6, B12 and C in Pregnancy
- (2012) Daphna K. Dror et al. PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
- Maternal Vitamin C Deficiency during Pregnancy Persistently Impairs Hippocampal Neurogenesis in Offspring of Guinea Pigs
- (2012) Pernille Tveden-Nyborg et al. PLoS One
- UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity
- (2012) C. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner
- (2012) G. G. Welstead et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vitamin C Enhances theIn vitroDevelopment of Porcine Pre-implantation Embryos by Reducing Oxidative Stress
- (2012) J Hu et al. REPRODUCTION IN DOMESTIC ANIMALS
- TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases
- (2012) Chih-Hung Hsu et al. Cell Reports
- UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development
- (2012) Karl B. Shpargel et al. PLoS Genetics
- Nitrosatable Drug Exposure During Early Pregnancy and Neural Tube Defects in Offspring
- (2011) Jean D. Brender et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Vitamin C enhances in vitro and in vivo development of porcine somatic cell nuclear transfer embryos
- (2011) Yongye Huang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A lymphoblast model for IDH2 gain-of-function activity in d-2-hydroxyglutaric aciduria type II: Novel avenues for biochemical and therapeutic studies
- (2011) M. Kranendijk et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells
- (2011) Ozlem Yildirim et al. CELL
- Regulation and function of DNA methylation in plants and animals
- (2011) Xin-Jian He et al. CELL RESEARCH
- Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
- (2011) Kian Peng Koh et al. Cell Stem Cell
- The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner
- (2011) Tao Wang et al. Cell Stem Cell
- Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine
- (2011) Atanu Maiti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sodium-Dependent Vitamin C Transporter 2 Deficiency Causes Hypomyelination and Extracellular Matrix Defects in the Peripheral Nervous System
- (2011) B. Gess et al. JOURNAL OF NEUROSCIENCE
- Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells
- (2011) Yufei Xu et al. MOLECULAR CELL
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- The Role of Vitamins in Cancer: A Review
- (2011) Ana Catarina Mamede et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos
- (2011) A. Inoue et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Molecular mechanisms regulating myelination in the peripheral nervous system
- (2011) Jorge A. Pereira et al. TRENDS IN NEUROSCIENCES
- Dietary ascorbate intake affects steady state tissue concentrations in vitamin C–deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit)
- (2010) Margreet CM Vissers et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Genetic variation at the SLC23A1 locus is associated with circulating concentrations of l-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants
- (2010) Nicholas J Timpson et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Prolyl 4-hydroxylase
- (2010) Kelly L. Gorres et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies
- (2010) Neil Justin et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Juvenile and adult olfactory ensheathing cells bundle and myelinate dorsal root ganglion axons in culture
- (2010) Joanne Babiarz et al. EXPERIMENTAL NEUROLOGY
- Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice
- (2010) Christopher P. Corpe et al. JOURNAL OF CLINICAL INVESTIGATION
- Vitamin C Transporter Gene Polymorphisms, Dietary Vitamin C and Serum Ascorbic Acid
- (2010) Leah E. Cahill et al. Journal of Nutrigenetics and Nutrigenomics
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
- (2010) Myunggon Ko et al. NATURE
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Vitamin C Promotes Widespread Yet Specific DNA Demethylation of the Epigenome in Human Embryonic Stem Cells
- (2010) Tung-Liang Chung et al. STEM CELLS
- Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs
- (2009) Pernille Tveden-Nyborg et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003–2004 National Health and Nutrition Examination Survey (NHANES)
- (2009) Rosemary L Schleicher et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Vitamin C: update on physiology and pharmacology
- (2009) J Mandl et al. BRITISH JOURNAL OF PHARMACOLOGY
- Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in Poland
- (2009) Margaret E. Wright et al. EUROPEAN JOURNAL OF CANCER
- Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
- (2009) Lin T. Guey et al. EUROPEAN UROLOGY
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
- α-Tocopherol and l-ascorbic acid increase the in vitro development of IVM/IVF swamp buffalo ( Bubalus bubalis) embryos
- (2008) K. Saikhun et al. Animal
- Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter
- (2008) Peter Zimmermann et al. ARTHRITIS AND RHEUMATISM
- Plasma concentrations of ascorbic acid in parturients from a hospital in Southeast Brazil
- (2008) Andréia Madruga de Oliveira et al. CLINICAL NUTRITION
- Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population
- (2008) A. Mosdol et al. JOURNAL OF PUBLIC HEALTH
- Genetic Variation in Sodium-Dependent Vitamin C TransportersSLC23A1andSLC23A2and Risk of Advanced Colorectal Adenoma
- (2008) Hans Christian Erichsen et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Polymorphisms in the Estrogen Receptor 1 and Vitamin C and Matrix Metalloproteinase Gene Families Are Associated with Susceptibility to Lymphoma
- (2008) Christine F. Skibola et al. PLoS One
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