CD44 in Ovarian Cancer Progression and Therapy Resistance—A Critical Role for STAT3
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD44 in Ovarian Cancer Progression and Therapy Resistance—A Critical Role for STAT3
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-12-01
DOI
10.3389/fonc.2020.589601
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Tumor-Associated Macrophages: Recent Insights and Therapies
- (2020) Jiawei Zhou et al. Frontiers in Oncology
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- Expression of CD44v6-Containing Isoforms Influences Cisplatin Response in Gastric Cancer Cells
- (2020) Carla Pereira et al. Cancers
- The Role of Tumor-Associated Macrophages in the Progression and Chemoresistance of Ovarian Cancer
- (2020) Marek Nowak et al. Cells
- CD44v6 engages in colorectal cancer progression
- (2019) Lixin Ma et al. Cell Death & Disease
- The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics
- (2019) Marlena Beyreis et al. Cancers
- Lipid metabolism in cancer cells under metabolic stress
- (2019) Rimsha Munir et al. BRITISH JOURNAL OF CANCER
- Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway
- (2019) Yujia Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer
- (2019) Karolina Okła et al. Frontiers in Immunology
- Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer
- (2019) Thaïs Baert et al. Frontiers in Immunology
- B Cells as an Immune-Regulatory Signature in Ovarian Cancer
- (2019) Gupta et al. Cancers
- Effect of Tumor Burden on Tumor Aggressiveness and Immune Modulation in Prostate Cancer: Association with IL-6 Signaling
- (2019) Chun-Te Wu et al. Cancers
- CD44 splice variant (CD44v3) promotes progression of urothelial carcinoma of bladder through Akt/ERK/STAT3 pathways: novel therapeutic approach
- (2019) Vivek Anand et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
- (2019) Lea Monteran et al. Frontiers in Immunology
- CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1
- (2019) Jiayi Zhou et al. Frontiers in Oncology
- FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer
- (2019) Stephanie Annett et al. BRITISH JOURNAL OF CANCER
- PARP Inhibitor Resistance: A Tug-of-War in BRCA-Mutated Cells
- (2019) Sylvie M. Noordermeer et al. TRENDS IN CELL BIOLOGY
- Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively
- (2019) Mauro Sola-Penna et al. BRITISH JOURNAL OF CANCER
- Lipid Droplets Define a Sub-Population of Breast Cancer Stem Cells
- (2019) Benjamin J. Hershey et al. Journal of Clinical Medicine
- Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity
- (2019) Chin-Jui Wu et al. Cancers
- LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation
- (2018) Zhixian Fang et al. BIOMEDICINE & PHARMACOTHERAPY
- Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling
- (2018) Yingxia Ning et al. BIOMEDICINE & PHARMACOTHERAPY
- Ovarian cancer statistics, 2018
- (2018) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
- (2018) Debanjan Dhar et al. CANCER CELL
- Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer
- (2018) Xianmin Mu et al. CELL CYCLE
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- Mesenchymal splice isoform of CD44 (CD44s) promotes EMT/invasion and imparts stem-like properties to ovarian cancer cells
- (2018) Rahul Bhattacharya et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- IL-6/STAT3 pathway intermediates M1/M2 macrophage polarization during the development of hepatocellular carcinoma
- (2018) Zi Yin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The biology and role of CD44 in cancer progression: therapeutic implications
- (2018) Chen Chen et al. Journal of Hematology & Oncology
- Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
- (2018) Andras Ladanyi et al. ONCOGENE
- CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway
- (2018) Linlin Wang et al. ONCOLOGY REPORTS
- Surface markers of cancer stem-like cells of ovarian cancer and their clinical relevance
- (2018) Aleksandra Klemba et al. Wspolczesna Onkologia-Contemporary Oncology
- Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression
- (2018) Viktor Fleming et al. Frontiers in Immunology
- Overexpression of CD44 Standard Isoform Upregulates HIF-1α Signaling in Hypoxic Breast Cancer Cells
- (2018) Dayoung Ryu et al. Biomolecules & Therapeutics
- An open-label phase 1 trial of the safety and efficacy of daily subcutaneous SPL-108 injections when used in combination with paclitaxel in patients with platinum-resistant, CD44+, advanced ovarian epithelial cancer.
- (2018) Eugenia Girda et al. JOURNAL OF CLINICAL ONCOLOGY
- Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells
- (2018) Xiaojing Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- State-of-the-art strategies for targeting the DNA damage response in cancer
- (2018) Patrick G. Pilié et al. Nature Reviews Clinical Oncology
- PARP1 Suppresses the Transcription of PD-L1 by Poly(ADP-Ribosyl)ating STAT3
- (2018) Ling Ding et al. Cancer Immunology Research
- Cancer Associated Fibroblasts: Naughty Neighbors That Drive Ovarian Cancer Progression
- (2018) Subramanyam Dasari et al. Cancers
- STAT3 mediates resistance to anoikis and promotes invasiveness of nasopharyngeal cancer cells
- (2017) Chien-Hung Lin et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer
- (2017) Muhammad Alamgeer et al. INVESTIGATIONAL NEW DRUGS
- CD44+ fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling
- (2017) Yonglei Liu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Quantification of STAT3 and VEGF expression for molecular diagnosis of lymph node metastasis in breast cancer
- (2017) Yujuan Chen et al. MEDICINE
- Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia
- (2017) F Peng et al. ONCOGENE
- Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways
- (2017) Luoqi Jia et al. ONCOLOGY REPORTS
- Upregulation of IGF1 by tumor-associated macrophages promotes the proliferation and migration of epithelial ovarian cancer cells
- (2017) Li Liu et al. ONCOLOGY REPORTS
- A CD44v+ subpopulation of breast cancer stem-like cells with enhanced lung metastasis capacity
- (2017) Jing Hu et al. Cell Death & Disease
- MICU1 drives glycolysis and chemoresistance in ovarian cancer
- (2017) Prabir K. Chakraborty et al. Nature Communications
- Ascites-derived IL-6 and IL-10 synergistically expand CD14+HLA-DR-/low myeloid-derived suppressor cells in ovarian cancer patients
- (2017) Liangliang Wu et al. Oncotarget
- CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
- (2017) Lisa Mayr et al. Oncotarget
- Regulation of CD44v6 expression in gastric carcinoma by the IL-6/STAT3 signaling pathway and its clinical significance
- (2017) Yuan-Yuan Xu et al. Oncotarget
- Phosphorylation of STAT3 at Tyr705 regulates MMP-9 production in epithelial ovarian cancer
- (2017) Zan-Hui Jia et al. PLoS One
- Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling
- (2016) Huan Yan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ablation of CD44 induces glycolysis-to-oxidative phosphorylation transition via modulation of the c-Src-Akt-LKB1-AMPK pathway
- (2016) K. Nam et al. BIOCHEMICAL JOURNAL
- FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
- (2016) Xuguang Yang et al. CANCER RESEARCH
- Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer
- (2016) Weimin Wang et al. CELL
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Expression of Vascular Endothelial Growth Factor in Ovarian Cancer Inhibits Tumor Immunity through the Accumulation of Myeloid-Derived Suppressor Cells
- (2016) Naoki Horikawa et al. CLINICAL CANCER RESEARCH
- CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer
- (2016) Chunyan Zhang et al. IMMUNITY
- Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer
- (2016) Mingzhu Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- Precision targeted therapy of ovarian cancer
- (2016) Justin Sapiezynski et al. JOURNAL OF CONTROLLED RELEASE
- The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma
- (2016) W. Li et al. MOLECULAR CANCER RESEARCH
- Targeting metastasis-initiating cells through the fatty acid receptor CD36
- (2016) Gloria Pascual et al. NATURE
- Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target
- (2016) U Saini et al. ONCOGENE
- Clinical significance of CD44 variant 9 expression as a prognostic indicator in bladder cancer
- (2016) Keita Kobayashi et al. ONCOLOGY REPORTS
- The Development of an Angiogenic Protein “Signature” in Ovarian Cancer Ascites as a Tool for Biologic and Prognostic Profiling
- (2016) Sofia-Paraskevi Trachana et al. PLoS One
- The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
- (2016) Vinit Kumar et al. TRENDS IN IMMUNOLOGY
- Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia
- (2016) Norbert Vey et al. Oncotarget
- First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors
- (2016) C. Willemien Menke-van der Houven van Oordt et al. Oncotarget
- Targeting epithelial-mesenchymal transition and cancer stem cells for chemoresistant ovarian cancer
- (2016) Junli Deng et al. Oncotarget
- The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer
- (2016) Ranjeeta Thapa et al. Stem Cells International
- Ovarian cancer
- (2016) Ursula A. Matulonis et al. Nature Reviews Disease Primers
- A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction
- (2016) Marco Demaria et al. Aging-US
- CD44 as a potential diagnostic tumor marker
- (2015) Nawwaf Basakran SAUDI MEDICAL JOURNAL
- Regulatory B cells contribute to the impaired antitumor immunity in ovarian cancer patients
- (2015) Xin Wei et al. TUMOR BIOLOGY
- CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination
- (2015) Abhilash K. Ravindranath et al. Oncotarget
- Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer
- (2015) Yan Gao et al. Oncotarget
- Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer
- (2015) Huanjie Shao et al. Oncotarget
- Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target
- (2015) Yongmin Yan et al. Stem Cells Translational Medicine
- Modulation of CD44 Activity by A6-Peptide
- (2015) Malcolm Finlayson Frontiers in Immunology
- Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors
- (2015) Ayesha B. Alvero et al. Oncotarget
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Smoothened activates breast cancer stem-like cell and promotes tumorigenesis and metastasis of breast cancer
- (2014) Lixia Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients
- (2014) Johannes Landskron et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer
- (2014) Roheena Z. Panni et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
- (2014) W. M. Lau et al. CANCER RESEARCH
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patients
- (2014) Zhonghu Li et al. Diagnostic Pathology
- Antibody Against CD44s Inhibits Pancreatic Tumor Initiation and Postradiation Recurrence in Mice
- (2014) Ling Li et al. GASTROENTEROLOGY
- The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA-binding Protein AUF1
- (2014) Siti-Fauziah Hendrayani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells
- (2014) SANGMIN KIM et al. ONCOLOGY REPORTS
- Prognostic value of CD44 and CD44v6 expression in patients with non-small cell lung cancer: meta-analysis
- (2014) Hao Jiang et al. TUMOR BIOLOGY
- Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
- (2014) D Ciavardelli et al. Cell Death & Disease
- A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
- (2014) Meiying Zhang et al. Journal of Ovarian Research
- Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells
- (2013) Zhiqiang Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer
- (2013) Teng Ji et al. CANCER LETTERS
- TGF- Modulates Ovarian Cancer Invasion by Upregulating CAF-Derived Versican in the Tumor Microenvironment
- (2013) T.-L. Yeung et al. CANCER RESEARCH
- Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2
- (2013) Tracy X. Cui et al. IMMUNITY
- FoxP3 Acts as a Cotranscription Factor with STAT3 in Tumor-Induced Regulatory T Cells
- (2013) Dewan Md Sakib Hossain et al. IMMUNITY
- Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
- (2013) Bastian Höchst et al. JOURNAL OF HEPATOLOGY
- Targeting CD44-STAT3 Signaling by Gemini Vitamin D Analog Leads to Inhibition of Invasion in Basal-Like Breast Cancer
- (2013) Jae Young So et al. PLoS One
- High Expression of Lewis y Antigen and CD44 Is Correlated with Resistance to Chemotherapy in Epithelial Ovarian Cancers
- (2013) Zhenhua Hu et al. PLoS One
- Prognostic Significance of B-Cells and pSTAT3 in Patients with Ovarian Cancer
- (2013) Chunmei Yang et al. PLoS One
- CD44 Staining of Cancer Stem-Like Cells Is Influenced by Down-Regulation of CD44 Variant Isoforms and Up-Regulation of the Standard CD44 Isoform in the Population of Cells That Have Undergone Epithelial-to-Mesenchymal Transition
- (2013) Adrian Biddle et al. PLoS One
- B Cells Promote Tumor Progression via STAT3 Regulated-Angiogenesis
- (2013) Chunmei Yang et al. PLoS One
- Constitutive Activation of STAT3 Signaling Regulates hTERT and Promotes Stem Cell-Like Traits in Human Breast Cancer Cells
- (2013) Seyung S. Chung et al. PLoS One
- Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44
- (2013) S. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD44 Expressed on Cancer-Associated Fibroblasts Is a Functional Molecule Supporting the Stemness and Drug Resistance of Malignant Cancer Cells in the Tumor Microenvironment
- (2013) Yumi Kinugasa et al. STEM CELLS
- Ovarian cancer stem cells: Working towards the root of stemness
- (2012) Rosemary Foster et al. CANCER LETTERS
- Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
- (2012) Y. Y. Zaytseva et al. CANCER RESEARCH
- Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
- (2012) M. Tamada et al. CANCER RESEARCH
- CD44+/CD24− ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival
- (2012) Erhong Meng et al. CLINICAL & EXPERIMENTAL METASTASIS
- Lipid metabolism in cancer
- (2012) Claudio R. Santos et al. FEBS Journal
- MicroRNA-199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer-initiating cells
- (2012) Weiwei Cheng et al. FEBS Journal
- A phase II study of a urokinase-derived peptide (A6) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: A Gynecologic Oncology Group study
- (2012) Michael A. Gold et al. GYNECOLOGIC ONCOLOGY
- Depletion of Tregs for adoptive T-cell therapy using CD44 and CD137 as selection markers
- (2012) Brian G Till et al. Immunotherapy
- Leukotriene B4Receptor-2 Promotes Invasiveness and Metastasis of Ovarian Cancer Cells through Signal Transducer and Activator of Transcription 3 (STAT3)-dependent Up-regulation of Matrix Metalloproteinase 2
- (2012) Ji-Min Seo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD)
- (2012) Karl E. Miletti-González et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyaluronan Oligomers-HPMA Copolymer Conjugates for Targeting Paclitaxel to CD44-Overexpressing Ovarian Carcinoma
- (2012) Gal Journo-Gershfeld et al. PHARMACEUTICAL RESEARCH
- Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
- (2012) Toshifumi Yae et al. Nature Communications
- Ovarian cancer stem cells and inflammation
- (2011) Gil Mor et al. CANCER BIOLOGY & THERAPY
- Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis
- (2011) Zhiyong Mi et al. CARCINOGENESIS
- Basic and Therapeutic Aspects of Angiogenesis
- (2011) Michael Potente et al. CELL
- Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance
- (2011) Ayesha B. Alvero et al. CELL CYCLE
- Direct reprogramming of stem cell properties in colon cancer cells by CD44
- (2011) Ying-Jhen Su et al. EMBO JOURNAL
- CD44 mediates oligosaccharides of hyaluronan-induced proliferation, tube formation and signal transduction in endothelial cells
- (2011) Ying Zhi Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- IL-6 and leukemia-inhibitory factor are involved in the generation of tumor-associated macrophage: regulation by IFN-γ
- (2011) Pascale Jeannin et al. Immunotherapy
- CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
- (2011) Rhonda L. Brown et al. JOURNAL OF CLINICAL INVESTIGATION
- The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors
- (2011) Lauren L.C. Marotta et al. JOURNAL OF CLINICAL INVESTIGATION
- JAK2/STAT3 signaling pathway activation mediates tumor angiogenesis by upregulation of VEGF and bFGF in non-small-cell lung cancer
- (2011) Mei Zhao et al. LUNG CANCER
- A6 Peptide Activates CD44 Adhesive Activity, Induces FAK and MEK Phosphorylation, and Inhibits the Migration and Metastasis of CD44-Expressing Cells
- (2011) R. S. Piotrowicz et al. MOLECULAR CANCER THERAPEUTICS
- Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
- (2011) L Y W Bourguignon et al. ONCOGENE
- Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
- (2011) P Yue et al. ONCOGENE
- Deactivation of Signal Transducer and Activator of Transcription 3 Reverses Chemotherapeutics Resistance of Leukemia Cells via Down-Regulating P-gp
- (2011) Xulong Zhang et al. PLoS One
- Osteopontin Enhances the Expression and Activity of MMP-2 via the SDF-1/CXCR4 Axis in Hepatocellular Carcinoma Cell Lines
- (2011) Rihua Zhang et al. PLoS One
- Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial
- (2010) Peter Gibbs et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells
- (2010) Xiaolei Zhang et al. CANCER GENETICS AND CYTOGENETICS
- Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
- (2010) Kiyomi Takaishi et al. CANCER SCIENCE
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- Identification of cancer stem cell-like cells from human epithelial ovarian carcinoma cell line
- (2010) M. F. Shi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck
- (2010) Kazuaki Chikamatsu et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells
- (2009) Tie Liu et al. Biology Direct
- Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression
- (2009) H Chen et al. BRITISH JOURNAL OF CANCER
- A Phase 2, randomized, double-blind, placebo-controlled trial of clinical activity and safety of subcutaneous A6 in women with asymptomatic CA125 progression after first-line chemotherapy of epithelial ovarian cancer
- (2009) S.A. Ghamande et al. GYNECOLOGIC ONCOLOGY
- Acetylation and activation of STAT3 mediated by nuclear translocation of CD44
- (2009) Jia-Lin Lee et al. JOURNAL OF CELL BIOLOGY
- CD44 Costimulation Promotes FoxP3+ Regulatory T Cell Persistence and Function via Production of IL-2, IL-10, and TGF-
- (2009) P. L. Bollyky et al. JOURNAL OF IMMUNOLOGY
- CD44 expression during tumor progression of follicular lymphoma
- (2009) Harigaya ONCOLOGY REPORTS
- CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
- (2009) A. Chaudhry et al. SCIENCE
- Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors
- (2008) S. Zhang et al. CANCER RESEARCH
- Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells
- (2008) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice
- (2008) Maciej Kujawski et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinoma
- (2008) Herbert Riechelmann et al. ORAL ONCOLOGY
- Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
- (2008) David Naor et al. SEMINARS IN CANCER BIOLOGY
- STAT3: A critical transcription activator in angiogenesis
- (2007) Zhong Chen et al. MEDICINAL RESEARCH REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation