- Home
- Publications
- Publication Search
- Publication Details
Title
Ways into Understanding HIF Inhibition
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 1, Pages 159
Publisher
MDPI AG
Online
2021-01-06
DOI
10.3390/cancers13010159
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Romidepsin (FK228), An Histone Deacetylase Inhibitor, and its Analogues in Cancer Chemotherapy.
- (2020) Eftiola Pojani et al. CURRENT MEDICINAL CHEMISTRY
- The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease
- (2020) Pascaline Aimé et al. NEUROBIOLOGY OF DISEASE
- Creation of different bioluminescence resonance energy transfer based biosensors with high affinity to VEGF
- (2020) Constanze Stumpf et al. PLoS One
- Development of a Recombinant Monospecific Anti-PLGF Bivalent Nanobody and Evaluation of it in Angiogenesis Modulation
- (2020) Abolfazl Nikooharf et al. MOLECULAR BIOTECHNOLOGY
- Targeting the HIF2–VEGF axis in renal cell carcinoma
- (2020) Toni K. Choueiri et al. NATURE MEDICINE
- Current development of CBP/p300 inhibitors in the last decade
- (2020) Zhang-Xu He et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases
- (2020) Orjon Rroji et al. NEUROBIOLOGY OF DISEASE
- Roxadustat: First Global Approval
- (2019) Sohita Dhillon DRUGS
- Nanobody Conjugated Nanotubes for Targeted Near-Infrared in vivo Imaging and Sensing
- (2019) Florian Alexander Mann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke
- (2019) Ishraq Alim et al. CELL
- Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
- (2019) Feng-cai Zhang et al. ACTA PHARMACOLOGICA SINICA
- Targeting mTOR for cancer therapy
- (2019) Hui Hua et al. Journal of Hematology & Oncology
- An Open-Label Phase I/IIa Study to Evaluate the Safety and Efficacy of CCS1477, a First in Clinic Inhibitor of the p300/CPB Bromodomains, As Monotherapy in Patients with Advanced Haematological Malignancies
- (2019) Tomasz Knurowski et al. BLOOD
- A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin
- (2019) Jussi-Pekka Tolonen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor in Clear Cell Renal Cell Carcinoma Patients
- (2019) Kevin D Courtney et al. CLINICAL CANCER RESEARCH
- Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
- (2018) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases
- (2018) Amit A. Joharapurkar et al. JOURNAL OF MEDICINAL CHEMISTRY
- Exploring the inhibition mechanism on HIF-2 by inhibitor PT2399 and 0X3 using molecular dynamics simulations
- (2018) Dong-Ru Sun et al. JOURNAL OF MOLECULAR RECOGNITION
- Inflammation and Hypoxia: HIF and PHD Isoform Selectivity
- (2018) Emily R. Watts et al. TRENDS IN MOLECULAR MEDICINE
- Optical analysis of cellular oxygen sensing
- (2017) Katrin Prost-Fingerle et al. EXPERIMENTAL CELL RESEARCH
- Human Epidermal Growth Factor Receptor 3–Specific Tumor Uptake and Biodistribution of 89 Zr-MSB0010853 Visualized by Real-Time and Noninvasive PET Imaging
- (2017) Frank J. Warnders et al. JOURNAL OF NUCLEAR MEDICINE
- HIF-3α Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC–ROCK1 Signaling Pathway
- (2017) Xianfei Zhou et al. MOLECULAR CANCER RESEARCH
- Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma
- (2017) Ahmet Krasniqi et al. MOLECULAR CANCER THERAPEUTICS
- Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha
- (2017) Chao Zhang et al. Oncotarget
- Nanobody-Based Delivery Systems for Diagnosis and Targeted Tumor Therapy
- (2017) Yaozhong Hu et al. Frontiers in Immunology
- Results from a phase I, dose-escalation study of PX-478, an orally available inhibitor of HIF-1α.
- (2017) R. Tibes et al. JOURNAL OF CLINICAL ONCOLOGY
- A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells
- (2017) Alexander Balhuizen et al. Scientific Reports
- A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
- (2016) Eli M. Wallace et al. CANCER RESEARCH
- Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities
- (2016) Sam Massa et al. Contrast Media & Molecular Imaging
- Targeting renal cell carcinoma with a HIF-2 antagonist
- (2016) Wenfang Chen et al. NATURE
- On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
- (2016) Hyejin Cho et al. NATURE
- Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound
- (2016) Kyunghye Park et al. Oncotarget
- A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system
- (2016) Takahiro Kuchimaru et al. Scientific Reports
- The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis
- (2015) Su Young Oh et al. MOLECULES AND CELLS
- Molecular pathogenesis of retinal and choroidal vascular diseases
- (2015) Peter A. Campochiaro PROGRESS IN RETINAL AND EYE RESEARCH
- Target engagement and drug residence time can be observed in living cells with BRET
- (2015) Matthew B. Robers et al. Nature Communications
- Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis
- (2015) Yen-Chia Huang et al. Oncotarget
- Tetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1α in cancer cells
- (2015) Kyu Kwang Kim et al. Scientific Reports
- Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma
- (2015) Tiansuo Zhao et al. Oncotarget
- Translational Impact of Nanoparticle-Drug Conjugate CRLX101 with or without Bevacizumab in Advanced Ovarian Cancer
- (2014) E. Pham et al. CLINICAL CANCER RESEARCH
- Belinostat: First Global Approval
- (2014) Raewyn M. Poole DRUGS
- A Group of Novel HIF-1α Inhibitors, Glyceollins, Blocks HIF-1α Synthesis and Decreases Its Stability via Inhibition of the PI3K/AKT/mTOR Pathway and Hsp90 Binding
- (2014) Sun-Hee Lee et al. JOURNAL OF CELLULAR PHYSIOLOGY
- NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction
- (2014) Ki Hyun Kim et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia
- (2014) Peng Zhang et al. Cell Reports
- A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells
- (2013) Elena Miranda et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Allosteric inhibition of hypoxia inducible factor-2 with small molecules
- (2013) Thomas H Scheuermann et al. Nature Chemical Biology
- Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation
- (2013) Manuela Delvecchio et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Romidepsin for Cutaneous T-cell Lymphoma
- (2012) H. M. Prince et al. CLINICAL CANCER RESEARCH
- Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer
- (2012) Steve Schoonooghe et al. IMMUNOBIOLOGY
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging
- (2012) Liqin Xiong et al. Nature Communications
- Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects
- (2011) Puja Sapra et al. ANGIOGENESIS
- Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity
- (2011) Zhi-Qiang Ning et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Inhibition of 2-oxoglutarate dependent oxygenases
- (2011) Nathan R. Rose et al. CHEMICAL SOCIETY REVIEWS
- Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells
- (2011) Christina D. Befani et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line
- (2010) Kyeong Lee et al. BIOCHEMICAL PHARMACOLOGY
- Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
- (2010) María Berdasco et al. DEVELOPMENTAL CELL
- Acute Hypoxia Induces HIF-Independent Monocyte Adhesion to Endothelial Cells through Increased Intercellular Adhesion Molecule-1 Expression: The Role of Hypoxic Inhibition of Prolyl Hydroxylase Activity for the Induction of NF- B
- (2010) S. Winning et al. JOURNAL OF IMMUNOLOGY
- The Current State of Chromatin Immunoprecipitation
- (2010) Philippe Collas MOLECULAR BIOTECHNOLOGY
- Molecular Imaging
- (2009) Rebecca Konietzny et al. Annals of the New York Academy of Sciences
- The humanHIF(hypoxia-inducible factor)-3α gene is a HIF-1 target gene and may modulate hypoxic gene induction
- (2009) Tetsuhiro Tanaka et al. BIOCHEMICAL JOURNAL
- A novel BRET-based genetically encoded biosensor for functional imaging of hypoxia
- (2009) Pablo Iglesias et al. BIOSENSORS & BIOELECTRONICS
- Histone acetyl transferases as emerging drug targets
- (2009) Frank J. Dekker et al. DRUG DISCOVERY TODAY
- Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor
- (2009) T. H. Scheuermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing
- (2008) U. Berchner-Pfannschmidt et al. EUROPEAN RESPIRATORY JOURNAL
- Modification of single molecule fluorescence near metallic nanostructures
- (2008) J.R. Lakowicz et al. Laser & Photonics Reviews
- Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1
- (2008) M. Y. Koh et al. MOLECULAR CANCER THERAPEUTICS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started