A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin

Primary endothelial–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia

(2019) Rafal Bartoszewski et al.   FASEB JOURNAL

Genetic variability of hypoxia‐inducible factor alpha ( HIFA ) genes in familial erythrocytosis: Analysis of the literature and genome databases

(2019) Aleša Kristan et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Physiology and pathophysiology of renal erythropoietin-producing cells

(2018) Hong-Mou Shih et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation

(2018) T. Drevytska et al.   LIFE SCIENCES

Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

(2018) James A Smythies et al.   EMBO REPORTS

Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype

(2018) Faik Imeri et al.   KIDNEY INTERNATIONAL

The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure

(2017) Allison E. McQueen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF-3α Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC–ROCK1 Signaling Pathway

(2017) Xianfei Zhou et al.   MOLECULAR CANCER RESEARCH

Angiopoietin-like 3 in lipoprotein metabolism

(2017) Sander Kersten   Nature Reviews Endocrinology

Hypoxia-inducible factor 3 biology: complexities and emerging themes

(2016) Cunming Duan   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex

(2016) Peng Zhang et al.   eLife

Ikaros and leukaemia

(2015) Linda Olsson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene

(2015) Satomi Kobayashi et al.   GENES TO CELLS

Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy

(2015) Stephen P. Zano et al.   MOLECULAR GENETICS AND METABOLISM

Erythropoietin Gene Expression: Developmental-Stage Specificity, Cell-Type Specificity, and Hypoxia Inducibility

(2015) Norio Suzuki   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction

(2014) L. Rahtu-Korpela et al.   DIABETES

Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance

(2014) Roberta Leonardi et al.   DIABETOLOGIA

A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression

(2014) F. Storti et al.   HAEMATOLOGICA

DNA methylation and body-mass index: a genome-wide analysis

(2014) Katherine J Dick et al.   LANCET

Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia

(2014) Peng Zhang et al.   Cell Reports

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance

(2013) Hirohide Matsuura et al.   CIRCULATION

SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor

(2013) Ville Paakinaho et al.   NUCLEIC ACIDS RESEARCH

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Angiopoietin-like 4 (Angptl4) Protein Is a Physiological Mediator of Intracellular Lipolysis in Murine Adipocytes

(2012) Nora E. Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

Chipster: user-friendly analysis software for microarray and other high-throughput data

(2011) M Aleksi Kallio et al.   BMC GENOMICS

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response

(2011) Minna Heikkilä et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

(2010) Christoph Loenarz et al.   EMBO REPORTS

Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2

(2010) Annika Pasanen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pantothenate Kinase 1 Is Required to Support the Metabolic Transition from the Fed to the Fasted State

(2010) Roberta Leonardi et al.   PLoS One

The humanHIF(hypoxia-inducible factor)-3α gene is a HIF-1 target gene and may modulate hypoxic gene induction

(2009) Tetsuhiro Tanaka et al.   BIOCHEMICAL JOURNAL

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION