Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases

(2020) Heng-Yi Chen et al.   JOURNAL OF IMMUNOLOGY

Galectin-9 and VISTA Expression Define Terminally Exhausted T Cells in HIV-1 Infection

(2020) Shima Shahbaz et al.   JOURNAL OF IMMUNOLOGY

Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders them to an Exhausted Phenotype in HIV-1 infection

(2020) Shokrollah Elahi et al.   PLoS Pathogens

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity

(2018) Qing Zhang et al.   NATURE IMMUNOLOGY

OUP accepted manuscript

(2018)   Journal of Crohns & Colitis

CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β

(2018) Shima Shahbaz et al.   PLOS BIOLOGY

Galectins and Carcinogenesis: Their Role in Head and Neck Carcinomas and Thyroid Carcinomas

(2017) Nadège Kindt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Erythroid Suppressor Cells Compromise Neonatal Immune Response againstBordetella pertussis

(2017) Garett Dunsmore et al.   JOURNAL OF IMMUNOLOGY

iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics

(2017) Lesley Seymour et al.   LANCET ONCOLOGY

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance

(2017) Donnele Daley et al.   NATURE MEDICINE

Defining an inflamed tumor immunophenotype in recurrent, metastatic squamous cell carcinoma of the head and neck

(2017) Glenn J. Hanna et al.   ORAL ONCOLOGY

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling

(2017) Isobel Okoye et al.   Oncotarget

NK Cell Exhaustion

(2017) Jiacheng Bi et al.   Frontiers in Immunology

Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer

(2017) Isobel S. Okoye et al.   Frontiers in Immunology

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

(2017) Isabel Gonçalves Silva et al.   EBioMedicine

Atorvastatin restricts HIV replication in CD4+ T cells by upregulation of p21

(2016) Shokrollah Elahi et al.   AIDS

Immunotherapy against cancer-related viruses

(2016) Haruko Tashiro et al.   CELL RESEARCH

CD14+ monocyte-derived galectin-9 induces natural killer cell cytotoxicity in chronic hepatitis C

(2016) Akira Nishio et al.   HEPATOLOGY

Abstract A008: Discriminant function for predicting survival of lung adenocarcinoma patients developed by using immune parameters of PD-L1, Gal-9, and XAGE1 expression on tumor cells and T cell infiltration score

(2016) Yoshihiro Ohue et al.   Cancer Immunology Research

Effector, Memory, and Dysfunctional CD8+T Cell Fates in the Antitumor Immune Response

(2016) John Reiser et al.   Journal of Immunology Research

The bitter side of sweet: the role of Galectin-9 in immunopathogenesis of viral infections

(2015) Shahzma Merani et al.   REVIEWS IN MEDICAL VIROLOGY

Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes

(2014) M. K. Keck et al.   CLINICAL CANCER RESEARCH

Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection

(2014) Alison Crawford et al.   IMMUNITY

Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

(2014) Chuan Wu et al.   IMMUNITY

Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies

(2014) Shravan Madireddi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Galectin-9 in tumor biology: A jack of multiple trades

(2013) Roy Heusschen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

(2013) Andrea Schietinger et al.   TRENDS IN IMMUNOLOGY

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

(2012) S. Elahi et al.   BLOOD

PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

(2012) C. Badoual et al.   CANCER RESEARCH

CD4+T Cells: Differentiation and Functions

(2012) Rishi Vishal Luckheeram et al.   Clinical & Developmental Immunology

Association of HLA-alleles with the immune regulation of chronic viral infections

(2012) Shokrollah Elahi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

(2011) Q. Zhou et al.   BLOOD

The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis

(2011) M J M Gooden et al.   BRITISH JOURNAL OF CANCER

Protective HIV-specific CD8+ T cells evade Treg cell suppression

(2011) Shokrollah Elahi et al.   NATURE MEDICINE

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

(2011) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectin-9 regulates T helper cell function independently of Tim-3

(2010) E. W. Su et al.   GLYCOBIOLOGY

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

(2009) Haina Shin et al.   IMMUNITY

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

(2009) N. Stanietsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA