Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders them to an Exhausted Phenotype in HIV-1 infection

Targeting B7‐1 in immunotherapy

(2019) Rui Chen et al.   MEDICINAL RESEARCH REVIEWS

Profound immune consequences for young adults infected with HIV perinatally or during childhood

(2019) Dionna W. Williams et al.   AIDS

Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

(2019) Aravindhan Ganesan et al.   Scientific Reports

Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control

(2018) Hayato Murakoshi et al.   EBioMedicine

CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β

(2018) Shima Shahbaz et al.   PLOS BIOLOGY

Erythroid Suppressor Cells Compromise Neonatal Immune Response againstBordetella pertussis

(2017) Garett Dunsmore et al.   JOURNAL OF IMMUNOLOGY

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling

(2017) Isobel Okoye et al.   Oncotarget

CD71+ erythroid suppressor cells impair adaptive immunity against Bordetella pertussis

(2017) Afshin Namdar et al.   Scientific Reports

Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?

(2017) Nicole B. Crux et al.   Frontiers in Immunology

Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer

(2017) Isobel S. Okoye et al.   Frontiers in Immunology

Atorvastatin restricts HIV replication in CD4+ T cells by upregulation of p21

(2016) Shokrollah Elahi et al.   AIDS

CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection

(2016) Marcus Buggert et al.   AIDS

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

(2015) Antoni Ribas et al.   LANCET ONCOLOGY

Rapid human immunodeficiency virus disease progression is associated with human leukocyte antigen-B homozygocity and human leukocyte antigen-B51 in a cohort from Manitoba, Canada

(2015) Yoav Keynan et al.   Infectious Diseases

Despite Biased TRBV Gene Usage against a Dominant HLA B57-Restricted Epitope, TCR Diversity Can Provide Recognition of Circulating Epitope Variants

(2014) B. C. Simons et al.   JOURNAL OF IMMUNOLOGY

Transcriptional regulation and T cell exhaustion

(2014) Matthew H. Collins et al.   Current Opinion in HIV and AIDS

T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection

(2014) Marcus Buggert et al.   PLoS Pathogens

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

(2012) S. Elahi et al.   BLOOD

The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection

(2012) Nabila Seddiki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Association of HLA-alleles with the immune regulation of chronic viral infections

(2012) Shokrollah Elahi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope

(2012) P. C. Matthews et al.   JOURNAL OF VIROLOGY

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

CTLA-4 blockade increases antigen-specific CD8+ T cells in prevaccinated patients with melanoma: three cases

(2011) Jianda Yuan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Protective HIV-specific CD8+ T cells evade Treg cell suppression

(2011) Shokrollah Elahi et al.   NATURE MEDICINE

Persistent Survival of Prevalent Clonotypes within an Immunodominant HIV Gag-Specific CD8+ T Cell Response

(2010) D. J. van Bockel et al.   JOURNAL OF IMMUNOLOGY

Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype

(2010) W. L. Dinges et al.   JOURNAL OF VIROLOGY

Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes

(2010) Christian B. Willberg et al.   PLoS One

The interplay between the geographic distribution of HLA-B27 alleles and their role in infectious and autoimmune diseases: A unifying hypothesis

(2009) Alessandro Mathieu et al.   AUTOIMMUNITY REVIEWS

A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

(2009) Haina Shin et al.   IMMUNITY

HLA-B*35-Px–mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses

(2009) Jinghe Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY