Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor

Internalization-dependent free fatty acid receptor 2 signaling is essential for propionate-induced anorectic gut hormone release

(2020) Natarin Caengprasath et al.   iScience

Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

(2019) Ross C. Anderson et al.   Frontiers in Endocrinology

Hardwiring wire-less networks: spatially encoded GPCR signaling in endocrine systems

(2019) Natarin Caengprasath et al.   CURRENT OPINION IN CELL BIOLOGY

Spatial encoding of GPCR signaling in the nervous system

(2019) Zara Y Weinberg et al.   CURRENT OPINION IN CELL BIOLOGY

Molecular Mechanisms of Action of FSH

(2019) Livio Casarini et al.   Frontiers in Endocrinology

Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors

(2018) Alex R.B. Thomsen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The hypothalamus-pituitary-gonad axis: Tales of mice and men

(2017) Athina Kaprara et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Functional selectivity of GPCR-directed drug action through location bias

(2017) Roshanak Irannejad et al.   Nature Chemical Biology

Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms

(2017) Silvia Sposini et al.   Cell Reports

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

(2016) Alex R.B. Thomsen et al.   CELL

Oral follicle-stimulating hormone agonist tested in healthy young women of reproductive age failed to demonstrate effect on follicular development but affected thyroid function

(2016) Mireille G.F. Gerrits et al.   FERTILITY AND STERILITY

Functional competence of a partially engaged GPCR–β-arrestin complex

(2016) Punita Kumari et al.   Nature Communications

Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays

(2015) Mohammed Akli Ayoub et al.   Frontiers in Endocrinology

Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors

(2015) Selvaraj G. Nataraja et al.   Frontiers in Endocrinology

Investigation of a thiazolidinone derivative as an allosteric modulator of follicle stimulating hormone receptor: Evidence for its ability to support follicular development and ovulation

(2014) Venkataraman Sriraman et al.   BIOCHEMICAL PHARMACOLOGY

Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators

(2014) Henry N. Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer

(2014) Xuliang Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling of an allosteric, nanomolar potent, low molecular weight agonist for the follicle-stimulating hormone receptor

(2013) Chris J. van Koppen et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of Follicle-Stimulating Hormone-Induced Preovulatory Follicles in Rats Treated with a Nonsteroidal Negative Allosteric Modulator of Follicle-Stimulating Hormone Receptor1

(2013) James A. Dias et al.   BIOLOGY OF REPRODUCTION

Spatially Restricted G Protein-coupled Receptor Activity via Divergent Endocytic Compartments

(2013) Frederic Jean-Alphonse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Kisspeptin Receptor Trafficking Modulates Kisspeptin-Mediated Calcium Signaling

(2013) Le Min et al.   MOLECULAR ENDOCRINOLOGY

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch

(2013) R. Vistein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis

(2013) Adam McCluskey et al.   TRAFFIC

Endocytosis Promotes Rapid Dopaminergic Signaling

(2011) Sarah J. Kotowski et al.   NEURON

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

A negative allosteric modulator demonstrates biased antagonism of the follicle stimulating hormone receptor

(2010) James A. Dias et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

(2009) Florian Mullershausen et al.   Nature Chemical Biology

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Differing pharmacological activities of thiazolidinone analogs at the FSH receptor

(2008) Brian J. Arey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications

(2007) Aylin C. Hanyaloglu et al.   Annual Review of Pharmacology and Toxicology