Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays

Dual agonist occupancy of AT1-R–α2C-AR heterodimers results in atypical Gs-PKA signaling

(2015) Morgane Bellot et al.   Nature Chemical Biology

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

(2015) Marjorie Damian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Interaction between Angiotensin II Receptor Type 1 and Chemokine (C-C Motif) Receptor 2 with Implications for Chronic Kidney Disease

(2015) Mohammed Akli Ayoub et al.   PLoS One

G Protein-Coupled Receptor Signaling Analysis Using Homogenous Time-Resolved Förster Resonance Energy Transfer (HTRF®) Technology

(2014) Lenea Nørskov-Lauritsen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spatially Restricted G Protein-coupled Receptor Activity via Divergent Endocytic Compartments

(2013) Frederic Jean-Alphonse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural biology of glycoprotein hormones and their receptors: Insights to signaling

(2013) Xuliang Jiang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Biased signalling in follicle stimulating hormone action

(2013) Flavie Landomiel et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Profiling Epidermal Growth Factor Receptor and Heregulin Receptor 3 Heteromerization Using Receptor Tyrosine Kinase Heteromer Investigation Technology

(2013) Mohammed Akli Ayoub et al.   PLoS One

Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling

(2012) Domitille Heitzler et al.   Molecular Systems Biology

Receptor-G Protein Interaction Studied by Bioluminescence Resonance Energy Transfer: Lessons from Protease-Activated Receptor 1

(2012) Mohammed Akli Ayoub et al.   Frontiers in Endocrinology

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

(2012) Martin Cottet et al.   Frontiers in Endocrinology

Decreased Degradation of Internalized Follicle-Stimulating Hormone Caused by Mutation of Aspartic Acid 6.30550 in a Protein Kinase-CK2 Consensus Sequence in the Third Intracellular Loop of Human Follicle-Stimulating Hormone Receptor1

(2011) Kerri S. Kluetzman et al.   BIOLOGY OF REPRODUCTION

The Adapter Protein APPL1 Links FSH Receptor to Inositol 1,4,5-Trisphosphate Production and Is Implicated in Intracellular Ca2+Mobilization

(2011) Richard M. Thomas et al.   ENDOCRINOLOGY

Internalization Dissociates β2-Adrenergic Receptors

(2011) Tien-Hung Lan et al.   PLoS One

Are circulating gonadotropin isoforms naturally occurring biased agonists? Basic and therapeutic implications

(2011) Brian J. Arey et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Novel pathways in gonadotropin receptor signaling and biased agonism

(2011) Alfredo Ulloa-Aguirre et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

β-arrestin-mediated receptor trafficking and signal transduction

(2011) Sudha K. Shenoy et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mapping the follicle-stimulating hormone-induced signaling networks

(2011) Pauline Gloaguen   Frontiers in Endocrinology

Differential association modes of the thrombin receptor PAR1 with Gαi1, Gα12, and β-arrestin 1

(2010) Mohammed Akli Ayoub et al.   FASEB JOURNAL

Preferential β-arrestin signalling at low receptor density revealed by functional characterization of the human FSH receptor A189 V mutation☆

(2010) Thibaud Tranchant et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Partially Deglycosylated Equine LH Preferentially Activates β-Arrestin-Dependent Signaling at the Follicle-Stimulating Hormone Receptor

(2010) Vanessa Wehbi et al.   MOLECULAR ENDOCRINOLOGY

Monitoring neural activity with bioluminescence during natural behavior

(2010) Eva A Naumann et al.   NATURE NEUROSCIENCE

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

(2010) A. Rivero-Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agonist efficacy and receptor desensitization: from partial truths to a fuller picture

(2009) Steven J Charlton   BRITISH JOURNAL OF PHARMACOLOGY

Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerization

(2009) Mohammed A Ayoub et al.   CURRENT OPINION IN PHARMACOLOGY

Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Gα Subunit

(2009) Mohammed Akli Ayoub et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Constitutively Active V2 Receptor Mutants Conferring NSIAD Are Weakly Sensitive to Agonist and Antagonist Regulation

(2009) Julie Tenenbaum et al.   PLoS One

Functional and Structural Roles of Conserved Cysteine Residues in the Carboxyl-Terminal Domain of the Follicle-Stimulating Hormone Receptor in Human Embryonic Kidney 293 Cells1

(2008) Aída Uribe et al.   BIOLOGY OF REPRODUCTION

Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells☆

(2008) Colette Galet et al.   CELLULAR SIGNALLING

Abundance and stability of complexes containing inactive G protein-coupled receptors and G proteins

(2008) Kou Qin et al.   FASEB JOURNAL