Pilot Production of SARS-CoV-2 Related Proteins in Plants: A Proof of Concept for Rapid Repurposing of Indoor Farms Into Biomanufacturing Facilities

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

(2020) Xiaolong Tian et al.   Emerging Microbes & Infections

High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System

(2020) Andrew G. Diamos et al.   Frontiers in Bioengineering and Biotechnology

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

(2020) Daniel Wrapp et al.   CELL

Evaluation of Nucleocapsid and Spike Protein-Based Enzyme-Linked Immunosorbent Assays for Detecting Antibodies against SARS-CoV-2

(2020) Wanbing Liu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A serological assay to detect SARS-CoV-2 seroconversion in humans

(2020) Fatima Amanat et al.   NATURE MEDICINE

Potential Applications of Plant Biotechnology against SARS-CoV-2

(2020) Teresa Capell et al.   TRENDS IN PLANT SCIENCE

Convalescent serum therapy for COVID-19: A 19th century remedy for a 21st century disease

(2020) Daniel Montelongo-Jauregui et al.   PLoS Pathogens

From Farm to Finger Prick—A Perspective on How Plants Can Help in the Fight Against COVID-19

(2020) Karen A. McDonald et al.   Frontiers in Bioengineering and Biotechnology

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

(2020) Anum Glasgow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plant Molecular Farming – Integration and Exploitation of Side Streams to Achieve Sustainable Biomanufacturing

(2019) Johannes F. Buyel   Frontiers in Plant Science

Transient Gene Expression Seeds Plant-Based Bioproduction Systems

(2019) Albor Dobon Alonso   Genetic Engineering & Biotechnology News

Building a global alliance of biofoundries

(2019) Nathan Hillson et al.   Nature Communications

Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti‐HIV‐1 Antibodies 2F5, 2G12, and PG9 in Plants

(2019) Alejandro A. Puchol Tarazona et al.   Biotechnology Journal

Development of Systems for the Production of Plant-Derived Biopharmaceuticals

(2019) Ki-Beom Moon et al.   Plants-Basel

High-level expression and enrichment of norovirus virus-like particles in plants using modified geminiviral vectors

(2018) Andrew G. Diamos et al.   PROTEIN EXPRESSION AND PURIFICATION

Improvement of the transient expression system for production of recombinant proteins in plants

(2018) Tsuyoshi Yamamoto et al.   Scientific Reports

Synthetic single domain antibodies for the conformational trapping of membrane proteins

(2018) Iwan Zimmermann et al.   eLife

GB3.0: a platform for plant bio-design that connects functional DNA elements with associated biological data

(2017) Marta Vazquez-Vilar et al.   NUCLEIC ACIDS RESEARCH

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins

(2017) Jose Manuel Julve Parreño et al.   PLANT BIOTECHNOLOGY JOURNAL

Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals

(2015) Barry R. Holtz et al.   PLANT BIOTECHNOLOGY JOURNAL

The human anti-HIV antibodies 2F5, 2G12, and PG9 differ in their susceptibility to proteolytic degradation: Down-regulation of endogenous serine and cysteine proteinase activities could improve antibody production in plant-based expression platforms

(2014) Melanie Niemer et al.   Biotechnology Journal

A coat-independent superinfection exclusion rapidly imposed in Nicotiana benthamiana cells by tobacco mosaic virus is not prevented by depletion of the movement protein

(2013) José Manuel Julve et al.   PLANT MOLECULAR BIOLOGY

GoldenBraid 2.0: A Comprehensive DNA Assembly Framework for Plant Synthetic Biology

(2013) A. Sarrion-Perdigones et al.   PLANT PHYSIOLOGY

Recombinant jacalin-like plant lectins are produced at high levels in Nicotiana benthamiana and retain agglutination activity and sugar specificity

(2012) Asun Fernandez-del-Carmen et al.   JOURNAL OF BIOTECHNOLOGY

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

(2012) G. G. Olinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GoldenBraid: An Iterative Cloning System for Standardized Assembly of Reusable Genetic Modules

(2011) Alejandro Sarrion-Perdigones et al.   PLoS One

pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants

(2009) Frank Sainsbury et al.   PLANT BIOTECHNOLOGY JOURNAL

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

Extremely High-Level and Rapid Transient Protein Production in Plants without the Use of Viral Replication

(2008) F. Sainsbury et al.   PLANT PHYSIOLOGY