Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Published 2020 View Full Article
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Title
Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Authors
Keywords
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Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-12-29
DOI
10.7554/elife.59659
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Note: Only part of the references are listed.- Joint Association Analysis Identified 18 New Loci for Bone Mineral Density
- (2019) Yu-Fang Pei et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
- (2019) Nina K. Serwas et al. Nature Communications
- Regulation of age-associated B cells by IRF5 in systemic autoimmunity
- (2018) Michela Manni et al. NATURE IMMUNOLOGY
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- (2018) Shi Bai et al. Scientific Reports
- PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression
- (2018) Satya K. Kota et al. BONE
- Bone protection by inhibition of microRNA-182
- (2018) Kazuki Inoue et al. Nature Communications
- Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption
- (2017) Nikolaus Binder et al. JOURNAL OF IMMUNOLOGY
- The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity
- (2017) Woelsung Yi et al. Nature Communications
- High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
- (2016) Celi Sun et al. NATURE GENETICS
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- SnapShot: Osteoimmunology
- (2015) Hiroshi Takayanagi Cell Metabolism
- RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis
- (2014) Susan Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca2+ signaling in T cells
- (2014) C. Fos et al. Science Signaling
- Osteoimmunology and Its Implications for Transplantation
- (2013) R. Pacifici AMERICAN JOURNAL OF TRANSPLANTATION
- Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
- (2013) Edward Y Chen et al. BMC BIOINFORMATICS
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- The multiple faces of proteinkinase R in antiviral defense
- (2013) Muhammad Munir et al. Virulence
- Osteoimmunology and Bone Homeostasis: Relevance to Spondyloarthritis
- (2013) Steven R. Goldring Current Rheumatology Reports
- Bone remodelling in inflammatory arthritis
- (2012) Steven R Goldring et al. ANNALS OF THE RHEUMATIC DISEASES
- Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling
- (2012) Daniel J. Gough et al. IMMUNITY
- Protein Kinase PKR Amplification of Interferon β Induction Occurs through Initiation Factor eIF-2α-mediated Translational Control
- (2012) Christopher S. McAllister et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment
- (2012) Georg Schett et al. Nature Reviews Rheumatology
- Protein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection
- (2012) Nora Taghavi et al. VIROLOGY
- IFNβ impairs extracellular matrix formation leading to inhibition of mineralization by effects in the early stage of human osteoblast differentiation
- (2011) V.J. Woeckel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Evidence of vitamin D and interferon-β cross-talk in human osteoblasts with 1α,25-dihydroxyvitamin D3 being dominant over interferon-β in stimulating mineralization
- (2011) V.J. Woeckel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cellular and Molecular Mechanisms of Bone Remodeling
- (2010) Liza J. Raggatt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Double-stranded RNA–dependent Protein Kinase Differentially Regulates Insulin Receptor Substrates 1 and 2 in HepG2 Cells
- (2010) Xuerui Yang et al. MOLECULAR BIOLOGY OF THE CELL
- Does Def6 Deficiency Cause Autoimmunity?
- (2009) Amnon Altman et al. IMMUNITY
- IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?
- (2009) Partha S. Biswas et al. IMMUNOLOGICAL REVIEWS
- Osteoblast Function Is Compromised at Sites of Focal Bone Erosion in Inflammatory Arthritis
- (2009) Nicole C Walsh et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis
- (2009) Baohong Zhao et al. NATURE MEDICINE
- Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R
- (2009) Christiane A. Opitz et al. STEM CELLS
- Osteoimmunology in rheumatic diseases
- (2009) Georg Schett ARTHRITIS RESEARCH & THERAPY
- IRF-4-Binding Protein Inhibits Interleukin-17 and Interleukin-21 Production by Controlling the Activity of IRF-4 Transcription Factor
- (2008) Qinzhong Chen et al. IMMUNITY
- Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases
- (2008) Qinzhong Chen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
- (2008) Anna Yarilina et al. NATURE IMMUNOLOGY
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