Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
Authors
Keywords
-
Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-11-25
DOI
10.7554/elife.62377
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate
- (2020) Yajing Gao et al. GASTROENTEROLOGY
- Autophagy promotes mammalian survival by suppressing oxidative stress and p53
- (2020) Yang Yang et al. GENES & DEVELOPMENT
- Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity
- (2020) Coralie Trentesaux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis
- (2019) Vrushank Bhatt et al. GENES & DEVELOPMENT
- Intestinal Epithelial Cell–Derived LKB1 Suppresses Colitogenic Microbiota
- (2018) Xia’nan Liu et al. JOURNAL OF IMMUNOLOGY
- Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
- (2018) Lillian J. Eichner et al. Cell Metabolism
- Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi
- (2017) Aimee Parker et al. FASEB JOURNAL
- KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
- (2017) Rachel L. Wolfson et al. NATURE
- Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes
- (2017) Monther Abu-Remaileh et al. SCIENCE
- SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
- (2017) Xin Gu et al. SCIENCE
- The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
- (2016) Lynne Chantranupong et al. CELL
- Death in the intestinal epithelium-basic biology and implications for inflammatory bowel disease
- (2016) J. Magarian Blander FEBS Journal
- Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
- (2016) Jessie Yanxiang Guo et al. GENES & DEVELOPMENT
- Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
- (2016) Robert A. Saxton et al. NATURE
- Deletion of Lkb1 in adult mice results in body weight reduction and lethality
- (2016) Tizhong Shan et al. Scientific Reports
- Autophagy and p53
- (2016) Eileen White Cold Spring Harbor Perspectives in Medicine
- Multiple amino acid sensing inputs to mTORC1
- (2015) Mitsugu Shimobayashi et al. CELL RESEARCH
- New developments in goblet cell mucus secretion and function
- (2015) G M H Birchenough et al. Mucosal Immunology
- Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
- (2015) S. Wang et al. SCIENCE
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- Differential regulation of mTORC1 by leucine and glutamine
- (2015) J. L. Jewell et al. SCIENCE
- Regulation of mTORC1 by amino acids
- (2014) Liron Bar-Peled et al. TRENDS IN CELL BIOLOGY
- Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
- (2014) G. Karsli-Uzunbas et al. Cancer Discovery
- Application and interpretation of current autophagy inhibitors and activators
- (2013) Ya-ping Yang et al. ACTA PHARMACOLOGICA SINICA
- The Intestinal Crypt, A Prototype Stem Cell Compartment
- (2013) Hans Clevers CELL
- Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria
- (2013) Jamaal L. Benjamin et al. Cell Host & Microbe
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut
- (2012) Nadine Wittkopf et al. Clinical & Developmental Immunology
- Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
- (2012) Claudia Günther et al. GUT
- Sensing of energy and nutrients by AMP-activated protein kinase
- (2011) D Grahame Hardie AMERICAN JOURNAL OF CLINICAL NUTRITION
- The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
- (2011) Dan Egan et al. Autophagy
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
- The tumor suppressor kinase LKB1: lessons from mouse models
- (2011) S. Ollila et al. Journal of Molecular Cell Biology
- Impaired Gastric Gland Differentiation in Peutz-Jeghers Syndrome
- (2010) Lina Udd et al. AMERICAN JOURNAL OF PATHOLOGY
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
- (2010) Daisuke Nakada et al. NATURE
- The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
- (2010) Sushma Gurumurthy et al. NATURE
- Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
- (2010) Boyi Gan et al. NATURE
- Effect ofHelicobacter pylori’s vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells
- (2009) Mauricio R. Terebiznik et al. Autophagy
- Autophagy, Immunity, and Microbial Adaptations
- (2009) Vojo Deretic et al. Cell Host & Microbe
- Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
- (2009) Boris Y. Shorning et al. PLoS One
- Induction of autophagy by anthrax lethal toxin
- (2008) Yian Kim Tan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- LKB1 in endothelial cells is required for angiogenesis and TGF -mediated vascular smooth muscle cell recruitment
- (2008) A. Londesborough et al. DEVELOPMENT
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- AMPK: a metabolic gauge regulating whole-body energy homeostasis
- (2008) Ricardo Lage et al. TRENDS IN MOLECULAR MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started