PEA15 loss of function and defective cerebral development in the domestic cat

Targetting PED/PEA-15 for diabetes treatment

(2017) Francesca Fiory et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Molecular modeling in the age of clinical genomics, the enterprise of the next generation

(2017) Jeremy W. Prokop et al.   JOURNAL OF MOLECULAR MODELING

Folding of the Cerebral Cortex Requires Cdk5 in Upper-Layer Neurons in Gyrencephalic Mammals

(2017) Yohei Shinmyo et al.   Cell Reports

Whole genome sequencing in cats, identifies new models for blindness in AIPL1 and somite segmentation in HES7

(2016) Leslie A. Lyons et al.   BMC GENOMICS

Regional Variations in Brain Gyrification Are Associated with General Cognitive Ability in Humans

(2016) Michael D. Gregory et al.   CURRENT BIOLOGY

Comparison between fibroblast wound healing and cell random migration assays in vitro

(2016) Flora Ascione et al.   EXPERIMENTAL CELL RESEARCH

Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling

(2016) Rachel E. Exler et al.   EXPERIMENTAL CELL RESEARCH

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Unified representation of genetic variants

(2015) Adrian Tan et al.   BIOINFORMATICS

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

(2015) Yongwook Choi et al.   BIOINFORMATICS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications

(2014) Andy Rimmer et al.   NATURE GENETICS

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

(2014) Tao Sun et al.   NATURE REVIEWS NEUROSCIENCE

CrossMap: a versatile tool for coordinate conversion between genome assemblies

(2013) Hao Zhao et al.   BIOINFORMATICS

Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly

(2013) Karine Poirier et al.   NATURE GENETICS

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

(2013) Peter D. Mace et al.   Nature Communications

DELLY: structural variant discovery by integrated paired-end and split-read analysis

(2012) T. Rausch et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

PED/PEA-15 interacts with the 67 kD laminin receptor and regulates cell adhesion, migration, proliferation and apoptosis

(2011) Pietro Formisano et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms

(2011) Roberta Buonomo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Evolution of the Brain, the Human Nature of Cortical Circuits, and Intellectual Creativity

(2011) Javier DeFelipe   Frontiers in Neuroanatomy

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities

(2009) Joe W Ramos et al.   BMC NEUROSCIENCE