Molecular modeling in the age of clinical genomics, the enterprise of the next generation

Structural libraries of protein models for multiple species to understand evolution of the renin-angiotensin system

(2015) Jeremy W. Prokop et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs

(2014) Qi Zhao et al.   NUCLEIC ACIDS RESEARCH

Inhibitors of Apoptotic Proteins: New Targets for Anticancer Therapy

(2013) Mohammad Saleem et al.   Chemical Biology & Drug Design

X-linked inhibitor of apoptosis (XIAP) deficiency: The spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis

(2013) C. Speckmann et al.   CLINICAL IMMUNOLOGY

X-linked lymphoproliferative syndromes and related autosomal recessive disorders

(2013) André Veillette et al.   Current Opinion in Allergy and Clinical Immunology

XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling

(2013) Xing Huang et al.   EMBO JOURNAL

Disease-causing mutations in the XIAPBIR2 domain impair NOD2-dependent immune signalling

(2013) Rune Busk Damgaard et al.   EMBO Molecular Medicine

XIAP deficiency is a mendelian cause of late-onset IBD

(2013) Carsten Speckmann et al.   GUT

Targeting the XIAP/caspase-7 complex selectively kills caspase-3–deficient malignancies

(2013) Yuan-Feng Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential Mechanisms of Activation of the Ang Peptide Receptors AT1, AT2, and MAS: Using In Silico Techniques to Differentiate the Three Receptors

(2013) Jeremy W. Prokop et al.   PLoS One

Genomics in Clinical Practice: Lessons from the Front Lines

(2013) H. J. Jacob et al.   Science Translational Medicine

Phase I Trial of AEG35156 an Antisense Oligonucleotide to XIAP Plus Gemcitabine in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

(2012) Daruka Mahadevan et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

MobiDB: a comprehensive database of intrinsic protein disorder annotations

(2012) T. Di Domenico et al.   BIOINFORMATICS

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

GPS-YNO2: computational prediction of tyrosine nitration sites in proteins

(2011) Zexian Liu et al.   Molecular BioSystems

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

ELM--the database of eukaryotic linear motifs

(2011) H. Dinkel et al.   NUCLEIC ACIDS RESEARCH

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

GPS-SNO: Computational Prediction of Protein S-Nitrosylation Sites with a Modified GPS Algorithm

(2010) Yu Xue et al.   PLoS One

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

XIAP mediates NOD signaling via interaction with RIP2

(2009) A. Krieg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8

(2009) Elmar Krieger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Identification, analysis, and prediction of protein ubiquitination sites

(2009) Predrag Radivojac et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

CSS-Palm 2.0: an updated software for palmitoylation sites prediction

(2008) J. Ren et al.   PROTEIN ENGINEERING DESIGN & SELECTION