Notoginseng leaf triterpenes ameliorates mitochondrial oxidative injury via the NAMPT-SIRT1/2/3 signaling pathways in cerebral ischemic model rats

Activation of AMPK/SIRT1 axis is required for adiponectin-mediated preconditioning on myocardial ischemia-reperfusion (I/R) injury in rats

(2019) Maria Assunta Potenza et al.   PLoS One

Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy

(2019) Ping Zhou et al.   Cells

Nicotinamide Metabolism Modulates the Proliferation / Differentiation Balance and Senescence of Human Primary Keratinocytes

(2019) Chye Ling Tan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Resveratrol Promotes Diabetic Wound Healing via SIRT1-FOXO1-c-Myc Signaling Pathway-Mediated Angiogenesis

(2019) Xiaozhong Huang et al.   Frontiers in Pharmacology

Targeting NAMPT as a therapeutic strategy against stroke

(2019) Shu-Na Wang et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Is Reversed by SIRT1

(2019) Antje Garten et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Subcellular NAMPT‐mediated NAD + salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury

(2019) Xiaowan Wang et al.   JOURNAL OF NEUROCHEMISTRY

HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways

(2019) Xie et al.   Biomolecules

Antidepressant-like effects of the Guanxin Danshen formula via mediation of the CaMK II-CREB-BDNF signalling pathway in chronic unpredictable mild stress-induced depressive rats

(2019) Weijie Xie et al.   Annals of Translational Medicine

NAMPT maintains mitochondria content via NRF2-PPARα/AMPKα pathway to promote cell survival under oxidative stress

(2019) An Yu et al.   CELLULAR SIGNALLING

The NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning

(2018) Nathalie Khoury et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT2 Inhibition Confers Neuroprotection by Downregulation of FOXO3a and MAPK Signaling Pathways in Ischemic Stroke

(2018) David T. She et al.   MOLECULAR NEUROBIOLOGY

Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke

(2018) Rajkumar Verma et al.   Translational Stroke Research

Neuroprotective Effects of Radix Scrophulariae on Cerebral Ischemia and Reperfusion Injury via MAPK Pathways

(2018) Xiaobo Meng et al.   MOLECULES

The Role of SIRT3 in the Brain Under Physiological and Pathological Conditions

(2018) Elena Sidorova-Darmos et al.   Frontiers in Cellular Neuroscience

Mitochondria in Ischemic Stroke: New Insight and Implications

(2018) Fan Liu et al.   Aging and Disease

SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

(2018) Wenyu Zhao et al.   Frontiers in Physiology

Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies

(2018) Weijie Xie et al.   Cells

Differential protein acetylation assists import of excess SOD2 into mitochondria and mediates SOD2 aggregation associated with cardiac hypertrophy in the murine SOD2-tg heart

(2017) Liwen Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity

(2016) XIAO-DONG ZOU et al.   Molecular Medicine Reports

Protective approaches against myocardial ischemia reperfusion injury

(2016) Xianchi Li et al.   Experimental and Therapeutic Medicine

NAMPT-Mediated NAD + Biosynthesis Is Essential for Vision In Mice

(2016) Jonathan B. Lin et al.   Cell Reports

Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways

(2016) Yingli Yu et al.   Scientific Reports

Characterization of the SIRT family of NAD+-dependent protein deacetylases in the context of a mammalian model of hibernation, the thirteen-lined ground squirrel

(2015) Andrew N. Rouble et al.   CRYOBIOLOGY

SIRT3 protects cells from hypoxia via PGC-1α- and MnSOD-dependent pathways

(2015) Q. Wang et al.   NEUROSCIENCE

NAMPT as a Therapeutic Target against Stroke

(2015) Pei Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Extracellular Visfatin has Nicotinamide Phosphoribosyltransferase Enzymatic Activity and is Neuroprotective Against Ischemic Injury

(2014) Yan Zhao et al.   CNS Neuroscience & Therapeutics

Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation

(2014) Bo Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

Mitochondrial targets for volatile anesthetics against cardiac ischemia-reperfusion injury

(2014) Bhawana Agarwal et al.   Frontiers in Physiology

SirT1 Regulation of Antioxidant Genes Is Dependent on the Formation of a FoxO3a/PGC-1α Complex

(2013) Yolanda Olmos et al.   ANTIOXIDANTS & REDOX SIGNALING

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

NAD+ and Nicotinamide: Sex Differences in Cerebral Ischemia

(2013) C.S. Siegel et al.   NEUROSCIENCE

Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways

(2012) Nicoletta Guaragnella et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy

(2012) Andrew M. Walters et al.   CIRCULATION RESEARCH

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia

(2011) Shang-Der Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

(2011) Trent M Woodruff et al.   Molecular Neurodegeneration

Effects of clinical and laboratory variables and of pretreatment with cardiovascular drugs in acute ischaemic stroke: A retrospective chart review from the GIFA study

(2010) Antonino Tuttolomondo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications☆

(2009) Juan P. Bolaños et al.   ADVANCED DRUG DELIVERY REVIEWS

Acute Stroke Therapy 1981–2009*

(2009) Bernd Eckert   CLINICAL NEURORADIOLOGY

Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger Energetically Compromised Neurons

(2009) Dong Liu et al.   NEUROMOLECULAR MEDICINE

Neurogenesis directed by Sirt1

(2008) Sergiy Libert et al.   NATURE CELL BIOLOGY