Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum

An epigenetic map of malaria parasite development from host to vector

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Plasmodium falciparum GCN5 acetyltransferase follows a novel proteolytic processing pathway that is essential for its function

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Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

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Novel pfkelch13 gene polymorphism associates with artemisinin resistance in eastern India

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Cellular mechanisms of action and resistance of Plasmodium falciparum to artemisinin

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Garcinol Inhibits GCN5-Mediated Lysine Acetyltransferase Activity and Prevents Replication of the Parasite Toxoplasma gondii

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The threat of artemisinin resistant malaria in Southeast Asia

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Landscape and Dynamics of Transcription Initiation in the Malaria Parasite Plasmodium falciparum

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Surveillance of Artemisinin Resistance in Plasmodium falciparum in India Using the kelch13 Molecular Marker

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Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

(2015) Alassane Mbengue et al.   NATURE

Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis

(2015) Zhaorong Hu et al.   PLANT JOURNAL

A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppression

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Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

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Overexpression, Purification and Characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) Protein

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Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

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Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome

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Epigenetic regulation of the Plasmodium falciparum genome

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Silence, activate, poise and switch! Mechanisms of antigenic variation inPlasmodium falciparum

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Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

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Turning up the heat: heat stress induces markers of programmed cell death in Plasmodium falciparum in vitro

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Dynamic Epigenetic Regulation of Gene Expression during the Life Cycle of Malaria Parasite Plasmodium falciparum

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H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

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PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division

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Oxidative Stress in Malaria

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PK4, a eukaryotic initiation factor 2 (eIF2 ) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

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Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

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Toxoplasma gondii Lysine Acetyltransferase GCN5-A Functions in the Cellular Response to Alkaline Stress and Expression of Cyst Genes

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H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

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Artemisinin Resistance inPlasmodium falciparumMalaria

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Transcriptional control and gene silencing inPlasmodium falciparum

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Large-Scale Differential Proteome Analysis in Plasmodium falciparum under Drug Treatment

(2008) Judith Helena Prieto et al.   PLoS One

Model-based Analysis of ChIP-Seq (MACS)

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