MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-08
DOI
10.1038/s41419-020-03336-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway
- (2020) Jing Zhao et al. Cell Death & Disease
- Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression
- (2020) I-Han Wang et al. Cancers
- Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway
- (2019) Jie Hu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
- (2019) Zuzanna Tracz-Gaszewska et al. Cancers
- Acetyl-CoA carboxylase (ACC) as a therapeutic target for metabolic syndrome and recent developments in ACC1/2 inhibitors
- (2019) Leyuan Chen et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Mitochondrial fission causes cisplatin resistance under hypoxic conditions via ROS in ovarian cancer cells
- (2019) Youngjin Han et al. ONCOGENE
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice
- (2018) Albert G. Linden et al. JOURNAL OF LIPID RESEARCH
- SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
- (2018) Russell A. DeBose-Boyd et al. TRENDS IN BIOCHEMICAL SCIENCES
- Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer
- (2018) Yang-An Wen et al. Cell Death & Disease
- Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets
- (2018) Ádám Nagy et al. Scientific Reports
- Th-POK regulates mammary gland lactation through mTOR-SREBP pathway
- (2018) Rui Zhang et al. PLoS Genetics
- Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer
- (2018) Nikos Koundouros et al. Frontiers in Oncology
- Fatty acid oxidation: An emerging facet of metabolic transformation in cancer
- (2018) Yibao Ma et al. CANCER LETTERS
- Downregulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP-1c axis
- (2018) Ting Tao et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Fatty acid synthase (FASN) as a therapeutic target in breast cancer
- (2017) Javier A. Menendez et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
- (2017) Hitoshi Shimano et al. Nature Reviews Endocrinology
- Mitochondrial dynamics and cancer
- (2017) Paola Maycotte et al. TUMOR BIOLOGY
- Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression
- (2017) Ayano Kondo et al. Cell Reports
- MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff
- (2017) Rong Yu et al. Scientific Reports
- Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes
- (2016) D. D. Liu et al. Animal
- Mitochondrial fission and fusion
- (2016) H. Lee et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The Role of Cholesterol in Cancer
- (2016) Omer F. Kuzu et al. CANCER RESEARCH
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- HMGCR is up-regulated in gastric cancer and promotes the growth and migration of the cancer cells
- (2016) Li Chushi et al. GENE
- HMGCR positively regulated the growth and migration of glioblastoma cells
- (2016) Zhihua Qiu et al. GENE
- Mitochondria and Mitochondrial ROS in Cancer: Novel Targets for Anticancer Therapy
- (2016) Yuhui Yang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
- (2015) Zhaoyong Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer
- (2015) Jessica E. Stine et al. Oncotarget
- Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer
- (2015) Deliang Guo et al. CURRENT PHARMACEUTICAL DESIGN
- Up-Regulated FASN Expression Promotes Transcoelomic Metastasis of Ovarian Cancer Cell through Epithelial-Mesenchymal Transition
- (2014) Li Jiang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease
- (2014) Behzad Yeganeh et al. PHARMACOLOGY & THERAPEUTICS
- Cholesterol and Cancer, in the Balance
- (2014) S. Silvente-Poirot et al. SCIENCE
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats
- (2012) Sunil K. Joshi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dysregulation of the mevalonate pathway promotes transformation
- (2010) J. W. Clendening et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Akt–SREBP nexus: cell signaling meets lipid metabolism
- (2010) James R. Krycer et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started