Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice

Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity

(2017) Deqiang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

(2017) Samir Softic et al.   JOURNAL OF CLINICAL INVESTIGATION

Unraveling the Regulation of Hepatic Metabolism by Insulin

(2017) Paul M. Titchenell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

(2017) Archana Vijayakumar et al.   Cell Reports

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice

(2017) Shunxing Rong et al.   eLife

Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

(2017) Tara Jois et al.   Molecular Metabolism

Hepatic Elovl6 gene expression is regulated by the synergistic action of ChREBP and SREBP-1c

(2016) Jin-Sik Bae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

(2016) Samir Softic et al.   DIGESTIVE DISEASES AND SCIENCES

ChREBP regulates fructose-induced glucose production independently of insulin signaling

(2016) Mi-Sung Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis

(2016) Mark A. Herman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Liver X receptors at the intersection of lipid metabolism and atherogenesis

(2015) Stephen D. Lee et al.   ATHEROSCLEROSIS

Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin

(2015) Naravat Poungvarin et al.   ENDOCRINOLOGY

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression

(2015) Laurent Vergnes et al.   JOURNAL OF LIPID RESEARCH

Scap is required for sterol synthesis and crypt growth in intestinal mucosa

(2015) Matthew R. McFarlane et al.   JOURNAL OF LIPID RESEARCH

Tissue Specific Effects of Dietary Carbohydrates and Obesity on ChREBPα and ChREBPβ Expression

(2015) Alexis D. Stamatikos et al.   LIPIDS

Transcriptional regulation of hepatic lipogenesis

(2015) Yuhui Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism

(2015) Floriane Baraille et al.   PHYSIOLOGY

Insig Proteins Mediate Feedback Inhibition of Cholesterol Synthesis in the Intestine

(2013) Matthew R. McFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

(2013) Xu Xu et al.   SEMINARS IN LIVER DISEASE

Novel insights into ChREBP regulation and function

(2013) Gaëlle Filhoulaud et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

(2013) Kari T. Chambers et al.   Molecular Metabolism

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

(2012) Young-Ah Moon et al.   Cell Metabolism

ChREBP Mediates Glucose-Stimulated Pancreatic  -Cell Proliferation

(2012) M. R. Metukuri et al.   DIABETES

The Role of the Carbohydrate Response Element-Binding Protein in Male Fructose-Fed Rats

(2012) Derek M. Erion et al.   ENDOCRINOLOGY

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

(2012) Mark A. Herman et al.   NATURE

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

(2012) J. L. Owen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression

(2011) Yun-Seung Jeong et al.   PLoS One

Regulation of Cholesterol and Fatty Acid Synthesis

(2011) J. Ye et al.   Cold Spring Harbor Perspectives in Biology

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif

(2009) Y.-K. Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

(2008) Pierre-Damien Denechaud et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

(2008) D. Grimm et al.   JOURNAL OF VIROLOGY