Sequential targeting of YAP1 and p21 enhances the elimination of senescent cells induced by the BET inhibitor JQ1

Multiple roles and context-specific mechanisms underlying YAP and TAZ-mediated resistance to anti-cancer therapy

(2020) Francesca Reggiani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

(2019) Lina Fu et al.   PLOS BIOLOGY

HSP90 regulates osteosarcoma cell apoptosis by targeting the p53/TCF‐1‐mediated transcriptional network

(2019) Jie Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis

(2018) Shuai Ye et al.   CANCER RESEARCH

Biological aspects of chondrosarcoma: Leaps and hurdles

(2018) Benoîte Mery et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence

(2018) Giulia Santinon et al.   EMBO JOURNAL

YAP/TAZ upstream signals and downstream responses

(2018) Antonio Totaro et al.   NATURE CELL BIOLOGY

Two-Step Senescence-Focused Cancer Therapies

(2018) Cynthia J. Sieben et al.   TRENDS IN CELL BIOLOGY

A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma

(2018) Jingya Sun et al.   Theranostics

The Receptor for Hyaluronan-Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury

(2018) Zheng Cui et al.   MATRIX BIOLOGY

A comprehensive evaluation of Hippo pathway silencing in sarcomas

(2018) Nicole M. Merritt et al.   Oncotarget

The dynamic nature of senescence in cancer

(2018) Soyoung Lee et al.   NATURE CELL BIOLOGY

Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

(2018) Yujie Deng et al.   Nature Communications

The BET Bromodomain Inhibitor JQ1 Suppresses Chondrosarcoma Cell Growth via Regulation of YAP/p21/c-Myc Signaling

(2017) Huan-Tian Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

p21: A Two-Faced Genome Guardian

(2017) Alexandros G. Georgakilas et al.   TRENDS IN MOLECULAR MEDICINE

The emerging role of YAP/TAZ in mechanotransduction

(2017) Zahra Mohri et al.   Journal of Thoracic Disease

Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage

(2016) Ansar Karimian et al.   DNA REPAIR

LKB1 inhibits the proliferation of gastric cancer cells by suppressing the nuclear translocation of Yap and β-catenin

(2016) LIAN-GANG MA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Differentiation Induces Dramatic Changes in miRNA Profile, Where Loss of Dicer Diverts Differentiating SH-SY5Y Cells Toward Senescence

(2016) Abhishek Jauhari et al.   MOLECULAR NEUROBIOLOGY

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

(2016) Panagiotis Galanos et al.   NATURE CELL BIOLOGY

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth

(2016) X Deng et al.   ONCOGENE

Re-evaluation of the roles ofDROSHA,Exportin 5, andDICERin microRNA biogenesis

(2016) Young-Kook Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse

(2016) Marco Demaria et al.   Cancer Discovery

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

(2016) N. Tasdemir et al.   Cancer Discovery

TAZ and YAP are frequently activated oncoproteins in sarcomas

(2016) Colleen A. Fullenkamp et al.   Oncotarget

Sp1 regulates Raf/MEK/ERK-induced p21CIP1 transcription in TP53-mutated cancer cells

(2015) Mansi Karkhanis et al.   CELLULAR SIGNALLING

YAP/TAZ for cancer therapy: Opportunities and challenges (Review)

(2015) LIWEN GUO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Stiffness of cancer cells measured with an AFM indentation method

(2015) Kozaburo Hayashi et al.   Journal of the Mechanical Behavior of Biomedical Materials

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis

(2015) T. S. Karin Eisinger-Mathason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence versus apoptosis in chemotherapy

(2015) Stéphane Ansieau et al.   Oncotarget

YAP controls retinal stem cell DNA replication timing and genomic stability

(2015) Pauline Cabochette et al.   eLife

Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells

(2014) Huan-Tian Zhang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

(2014) Masaki Mori et al.   CELL

Senescence and apoptosis: dueling or complementary cell fates?

(2014) B. G. Childs et al.   EMBO REPORTS

OpenComet: An automated tool for comet assay image analysis

(2014) Benjamin M. Gyori et al.   Redox Biology

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

The Hippo Pathway Effectors TAZ/YAP Regulate Dicer Expression and MicroRNA Biogenesis through Let-7

(2013) Steven G. Chaulk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer

(2013) Eva J. Vlug et al.   CELLULAR ONCOLOGY

p21WAF1 and tumourigenesis

(2012) Noel A. Warfel et al.   CURRENT OPINION IN ONCOLOGY

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance

(2011) J. G. van Oosterwijk et al.   ANNALS OF ONCOLOGY

Cellular senescence in oral cancer and precancer and treatment implications: A review

(2008) Julian Campo-Trapero et al.   ACTA ONCOLOGICA

The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-κB target genes by interaction with NFKBIZ

(2008) M Göransson et al.   ONCOGENE