The Paradox of Astroglial Ca2 + Signals at the Interface of Excitation and Inhibition

Constitutive deletion of astrocytic connexins aggravates kainate-induced epilepsy

(2020) Tushar Deshpande et al.   GLIA

G-Protein-Coupled Receptors in Astrocyte–Neuron Communication

(2020) Paulo Kofuji et al.   NEUROSCIENCE

Astrocyte Signaling Gates Long-Term Depression at Corticostriatal Synapses of the Direct Pathway

(2020) Anna Cavaccini et al.   JOURNAL OF NEUROSCIENCE

Making sense of astrocytic calcium signals — from acquisition to interpretation

(2020) Alexey Semyanov et al.   NATURE REVIEWS NEUROSCIENCE

Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders

(2019) Eiji Shigetomi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gi/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission

(2019) Caitlin A. Durkee et al.   GLIA

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

(2019) Jun Nagai et al.   CELL

GABAergic‐astrocyte signaling: A refinement of inhibitory brain networks

(2019) Sara Mederos et al.   GLIA

Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression

(2019) Nathan A. Smith et al.   NEUROCHEMICAL RESEARCH

Bestrophin1‐mediated tonic GABA release from reactive astrocytes prevents the development of seizure‐prone network in kainate‐injected hippocampi

(2019) Sudip Pandit et al.   GLIA

The structural and functional evidence for vesicular release from astrocytes in situ

(2018) Kirsten Bohmbach et al.   BRAIN RESEARCH BULLETIN

Gliotransmission: Beyond Black-and-White

(2018) Iaroslav Savtchouk et al.   JOURNAL OF NEUROSCIENCE

Cortical Circuit Activity Evokes Rapid Astrocyte Calcium Signals on a Similar Timescale to Neurons

(2018) Jillian L. Stobart et al.   NEURON

Ventral midbrain astrocytes display unique physiological features and sensitivity to dopamine D2 receptor signaling

(2018) Wendy Xin et al.   NEUROPSYCHOPHARMACOLOGY

Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior

(2018) Sónia Guerra-Gomes et al.   Frontiers in Cellular Neuroscience

Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

(2018) Letizia Mariotti et al.   Nature Communications

Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model

(2018) Grace O. Mizuno et al.   Cell Reports

Neuronal activity determines distinct gliotransmitter release from a single astrocyte

(2018) Ana Covelo et al.   eLife

Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity

(2018) Kjell Heuser et al.   CEREBRAL CORTEX

Cholecystokinin switches the plasticity of GABA synapses in the dorsomedial hypothalamus via astrocytic ATP release

(2018) Karen M Crosby et al.   JOURNAL OF NEUROSCIENCE

Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior

(2018) Xinzhu Yu et al.   NEURON

Conditional Knockout of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake

(2018) Anthony D. Umpierre et al.   JOURNAL OF NEUROSCIENCE

Diversity and Specificity of Astrocyte–neuron Communication

(2018) Caitlin A. Durkee et al.   NEUROSCIENCE

Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

(2018) Marco Matos et al.   Nature Communications

The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction

(2018) Felix Chan et al.   BRAIN

Neuron-astrocyte signaling is preserved in the aging brain

(2017) Marta Gómez-Gonzalo et al.   GLIA

Astrocytic IP3Rs: Contribution to Ca2+signalling and hippocampal LTP

(2017) Mark William Sherwood et al.   GLIA

Epilepsy and astrocyte energy metabolism

(2017) Detlev Boison et al.   GLIA

Molecular and Functional Properties of Regional Astrocytes in the Adult Brain

(2017) Lydie Morel et al.   JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways

(2017) Yvonne Schwarz et al.   NATURE NEUROSCIENCE

Synapse-specific astrocyte gating of amygdala-related behavior

(2017) Mario Martin-Fernandez et al.   NATURE NEUROSCIENCE

Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes

(2017) Amit Agarwal et al.   NEURON

Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation

(2017) C.S. Copeland et al.   NEUROPHARMACOLOGY

Three-dimensional Ca2+imaging advances understanding of astrocyte biology

(2017) Erika Bindocci et al.   SCIENCE

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy

(2017) Edward Beamer et al.   Frontiers in Neuroscience

Extensive astrocyte synchronization advances neuronal coupling in slow wave activity in vivo

(2017) Zsolt Szabó et al.   Scientific Reports

Dopamine elevates and lowers astroglial Ca2+through distinct pathways depending on local synaptic circuitry

(2016) Alistair Jennings et al.   GLIA

Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice

(2016) R. Jiang et al.   JOURNAL OF NEUROSCIENCE

Astrocyte calcium signaling: the third wave

(2016) Narges Bazargani et al.   NATURE NEUROSCIENCE

Glia as drivers of abnormal neuronal activity

(2016) Stefanie Robel et al.   NATURE NEUROSCIENCE

Adenosinergic signaling in epilepsy

(2016) Detlev Boison   NEUROPHARMACOLOGY

Crucial role of astrocytes in temporal lobe epilepsy

(2016) C. Steinhäuser et al.   NEUROSCIENCE

Astrocytic mGluR5 and the tripartite synapse

(2016) A. Panatier et al.   NEUROSCIENCE

Astrocytes regulate heterogeneity of presynaptic strengths in hippocampal networks

(2016) Mathieu Letellier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes regulate cortical state switching in vivo

(2016) Kira E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic GABA transporter activity modulates excitatory neurotransmission

(2016) Kim Boddum et al.   Nature Communications

Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks

(2016) Gertrudis Perea et al.   eLife

ATP from synaptic terminals and astrocytes regulates NMDA receptors and synaptic plasticity through PSD-95 multi-protein complex

(2016) U. Lalo et al.   Scientific Reports

Astrocyte uncoupling as a cause of human temporal lobe epilepsy

(2015) Peter Bedner et al.   BRAIN

Regulation of neuronal communication by G protein-coupled receptors

(2015) Yunhong Huang et al.   FEBS LETTERS

Enhanced astroglial Ca2+signaling increases excitatory synaptic strength in the epileptic brain

(2015) Carla Álvarez-Ferradas et al.   GLIA

The inhibitory neurotransmitter GABA evokes long-lasting Ca2+oscillations in cortical astrocytes

(2015) Letizia Mariotti et al.   GLIA

Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?

(2015) Jessica L. Seidel et al.   GLIA

Ca2+ signaling in astrocytes from Ip3r2 −/− mice in brain slices and during startle responses in vivo

(2015) Rahul Srinivasan et al.   NATURE NEUROSCIENCE

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

Disentangling calcium-driven astrocyte physiology

(2015) Dmitri A. Rusakov   NATURE REVIEWS NEUROSCIENCE

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

(2015) R. Martin et al.   SCIENCE

Role of Astrocytes in Epilepsy

(2015) D. A. Coulter et al.   Cold Spring Harbor Perspectives in Medicine

Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model

(2015) Oleg Yarishkin et al.   Experimental Neurobiology

Astrocyte calcium signalling orchestrates neuronal synchronization in organotypic hippocampal slices

(2014) Takuya Sasaki et al.   JOURNAL OF PHYSIOLOGY-LONDON

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Conditions and Constraints for Astrocyte Calcium Signaling in the Hippocampal Mossy Fiber Pathway

(2014) Martin D. Haustein et al.   NEURON

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Norepinephrine Controls Astroglial Responsiveness to Local Circuit Activity

(2014) Martin Paukert et al.   NEURON

GABAB receptor-mediated activation of astrocytes by gamma-hydroxybutyric acid

(2014) T. Gould et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

GABA as a rising gliotransmitter

(2014) Bo-Eun Yoon et al.   Frontiers in Neural Circuits

Exocytosis of ATP From Astrocytes Modulates Phasic and Tonic Inhibition in the Neocortex

(2014) Ulyana Lalo et al.   PLOS BIOLOGY

Astrocyte calcium microdomains are inhibited by Bafilomycin A1 and cannot be replicated by low-level Schaffer collateral stimulation in situ

(2013) Min-Yu Sun et al.   CELL CALCIUM

Transporter-mediated replacement of extracellular glutamate for GABA in the developing murine neocortex

(2013) Petr Unichenko et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses

(2013) Eiji Shigetomi et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Expression of Kainate Receptor Subunits in Hippocampal Astrocytes After Experimentally Induced Status Epilepticus

(2013) Jay R. Vargas et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Photolysis of Caged Ca2+ But Not Receptor-Mediated Ca2+ Signaling Triggers Astrocytic Glutamate Release

(2013) F. Wang et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of heterosynaptic metaplasticity

(2013) S. R. Hulme et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Glutamate-Dependent Neuroglial Calcium Signaling Differs Between Young and Adult Brain

(2013) W. Sun et al.   SCIENCE

Astrocytes convert network excitation to tonic inhibition of neurons

(2012) László Héja et al.   BMC BIOLOGY

TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation

(2012) Dong Ho Woo et al.   CELL

Astrocyte calcium signaling and epilepsy

(2012) Giorgio Carmignoto et al.   GLIA

Heterosynaptic long-term depression mediated by ATP released from astrocytes

(2012) Jiadong Chen et al.   GLIA

Hippocampal tissue of patients with refractory temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors

(2012) A. Das et al.   NEUROSCIENCE

Bergmann Glial AMPA Receptors Are Required for Fine Motor Coordination

(2012) A. S. Saab et al.   SCIENCE

GABA release by hippocampal astrocytes

(2012) Karim Le Meur et al.   Frontiers in Computational Neuroscience

Age-dependent remodelling of ionotropic signalling in cortical astroglia

(2011) Ulyana Lalo et al.   AGING CELL

Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses

(2011) Aude Panatier et al.   CELL

Locally Synchronized Astrocytes

(2011) Takuya Sasaki et al.   CEREBRAL CORTEX

Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABAA receptors

(2011) Cristina Jiménez-González et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Sustained Neuronal Activity Generated by Glial Plasticity

(2011) T. M. Pirttimaki et al.   JOURNAL OF NEUROSCIENCE

Calcium signalling in astroglia

(2011) Alexei Verkhratsky et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

How Inhibition Shapes Cortical Activity

(2011) Jeffry S. Isaacson et al.   NEURON

Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures

(2011) Hiram Luna-Munguia et al.   NEUROPHARMACOLOGY

Astrocytic regulation of cortical UP states

(2011) K. E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum

(2011) Bo-Eun Yoon et al.   Molecular Brain

Ca2+ sources for the exocytotic release of glutamate from astrocytes

(2010) Vladimir Parpura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes

(2010) Oleg Palygin et al.   CELL CALCIUM

Astrocyte heterogeneity: an underappreciated topic in neurobiology

(2010) Ye Zhang et al.   CURRENT OPINION IN NEUROBIOLOGY

Astrocytes are GABAergic cells that modulate microglial activity

(2010) Moonhee Lee et al.   GLIA

Neuron–astrocyte interactions in the medial nucleus of the trapezoid body

(2010) Daniel Reyes-Haro et al.   JOURNAL OF GENERAL PHYSIOLOGY

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Glial cells in neuronal network function

(2010) A. Araque et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Channel-Mediated Tonic GABA Release from Glia

(2010) S. Lee et al.   SCIENCE

An Excitatory Loop with Astrocytes Contributes to Drive Neurons to Seizure Threshold

(2010) Marta Gómez-Gonzalo et al.   PLOS BIOLOGY

Gliotransmission: Exocytotic release from astrocytes

(2009) Vladimir Parpura et al.   BRAIN RESEARCH REVIEWS

Bestrophin-1 Encodes for the Ca2+-Activated Anion Channel in Hippocampal Astrocytes

(2009) H. Park et al.   JOURNAL OF NEUROSCIENCE

Motor Behavior Activates Bergmann Glial Networks

(2009) Axel Nimmerjahn et al.   NEURON

GABA uptake-dependent Ca2+ signaling in developing olfactory bulb astrocytes

(2009) M. Doengi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes

(2008) Silke D. Meier et al.   GLIA

Differential NMDA-dependent activation of glial cells in mouse hippocampus

(2008) Alexandre Serrano et al.   GLIA

Two Forms of Astrocyte Calcium Excitability Have Distinct Effects on NMDA Receptor-Mediated Slow Inward Currents in Pyramidal Neurons

(2008) E. Shigetomi et al.   JOURNAL OF NEUROSCIENCE

Tuned Responses of Astrocytes and Their Influence on Hemodynamic Signals in the Visual Cortex

(2008) J. Schummers et al.   SCIENCE