Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?

Astrocyte-Mediated Ischemic Tolerance

(2015) Y. Hirayama et al.   JOURNAL OF NEUROSCIENCE

Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance

(2014) Jessica L. Seidel et al.   GLIA

Spreading Depolarization-Induced Adenosine Accumulation Reflects Metabolic Status In Vitro and In Vivo

(2014) Britta E Lindquist et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Detecting Tissue Deterioration after Brain Injury: Regional Blood Flow Level versus Capacity to Raise Blood Flow

(2014) Delphine Feuerstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

(2014) T. Fujita et al.   JOURNAL OF NEUROSCIENCE

Astrocyte glycogen as an emergency fuel under conditions of glucose deprivation or intense neural activity

(2014) Angus M. Brown et al.   METABOLIC BRAIN DISEASE

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

(2014) Ulrike Pannasch et al.   NATURE NEUROSCIENCE

Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations

(2014) Daniela Pietrobon et al.   NATURE REVIEWS NEUROSCIENCE

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex

(2014) Renán Sánchez-Porras et al.   NEUROPHARMACOLOGY

Hemichannels: new roles in astroglial function

(2014) Juan A. Orellana et al.   Frontiers in Physiology

Continuous Online Microdialysis Using Microfluidic Sensors: Dynamic Neurometabolic Changes during Spreading Depolarization

(2013) Michelle L. Rogers et al.   ACS Chemical Neuroscience

Evolution of neuronal and astroglial disruption in the peri-contusional cortex of mice revealed by in vivo two-photon imaging

(2013) Jeremy Sword et al.   BRAIN

Cortical spreading depression-induced preconditioning in mouse neocortex is lamina specific

(2013) Helen M. Gniel et al.   JOURNAL OF NEUROPHYSIOLOGY

Increased 20-HETE Synthesis Explains Reduced Cerebral Blood Flow But Not Impaired Neurovascular Coupling after Cortical Spreading Depression in Rat Cerebral Cortex

(2013) J. C. Fordsmann et al.   JOURNAL OF NEUROSCIENCE

Inhibition of a SNARE-Sensitive Pathway in Astrocytes Attenuates Damage following Stroke

(2013) D. J. Hines et al.   JOURNAL OF NEUROSCIENCE

Neuronal D-Serine and Glycine Release Via the Asc-1 Transporter Regulates NMDA Receptor-Dependent Synaptic Activity

(2013) D. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

Cortical spreading depression and migraine

(2013) Andrew C. Charles et al.   Nature Reviews Neurology

Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels

(2013) H. Karatas et al.   SCIENCE

Casein Kinase I  Mutations in Familial Migraine and Advanced Sleep Phase

(2013) K. C. Brennan et al.   Science Translational Medicine

Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury

(2012) D. N. Hertle et al.   BRAIN

Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons

(2012) Michael A. Benneyworth et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury

(2012) Ulrike Hoffmann et al.   EXPERIMENTAL NEUROLOGY

The Importance of astrocyte-derived purines in the modulation of sleep

(2012) Tamara Blutstein et al.   GLIA

Persistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations

(2012) W. Christopher Risher et al.   GLIA

Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling

(2012) Christian Steinhäuser et al.   GLIA

Artifact versus reality-How astrocytes contribute to synaptic events

(2012) Maiken Nedergaard et al.   GLIA

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons

(2012) Isamu Aiba et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices

(2012) B.E. Lindquist et al.   NEUROSCIENCE

Is Spreading Depolarization Characterized by an Abrupt, Massive Release of Gibbs Free Energy from the Human Brain Cortex?

(2012) Jens P. Dreier et al.   NEUROSCIENTIST

Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity

(2012) D. Lovatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

(2012) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusters of Spreading Depolarizations Are Associated With Disturbed Cerebral Metabolism in Patients With Aneurysmal Subarachnoid Hemorrhage

(2012) Oliver W. Sakowitz et al.   STROKE

Chronic daily cortical spreading depressions suppress spreading depression susceptibility

(2011) Inna Sukhotinsky et al.   CEPHALALGIA

Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway

(2011) Qiudong Deng et al.   GLIA

Cultured Astrocytes do not Release Adenosine during Hypoxic Conditions

(2011) Takumi Fujita et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spreading depolarisations and outcome after traumatic brain injury: a prospective observational study

(2011) Jed A Hartings et al.   LANCET NEUROLOGY

Signaling Pathways in Reactive Astrocytes, a Genetic Perspective

(2011) Wenfei Kang et al.   MOLECULAR NEUROBIOLOGY

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

(2011) Jens P Dreier   NATURE MEDICINE

Role of Astrocytes in Neurovascular Coupling

(2011) Gabor C. Petzold et al.   NEURON

Contribution of astrocyte glycogen stores to progression of spreading depression and related events in hippocampal slices

(2011) J.L. Seidel et al.   NEUROSCIENCE

Astroglial networks scale synaptic activity and plasticity

(2011) U. Pannasch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc: new clues to diverse roles in brain ischemia

(2011) C. William Shuttleworth et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Increased Susceptibility to Cortical Spreading Depression in the Mouse Model of Familial Hemiplegic Migraine Type 2

(2011) Loredana Leo et al.   PLoS Genetics

Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression

(2010) Joshua C. Chang et al.   BRAIN

Transient Swelling, Acidification, and Mitochondrial Depolarization Occurs in Neurons but not Astrocytes during Spreading Depression

(2010) Ning Zhou et al.   CEREBRAL CORTEX

Cortical Spreading Depression and Migraine

(2010) Katharina Eikermann-Haerter et al.   Current Neurology and Neuroscience Reports

The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

(2010) Thomas Misje Mathiisen et al.   GLIA

Cortical Spreading Depression Triggers Migraine Attack: Pro

(2010) Cenk Ayata   HEADACHE

Spreading Depression and Related Events Are Significant Sources of Neuronal Zn2+ Release and Accumulation

(2010) Russell E Carter et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dynamic Metabolic Response to Multiple Spreading Depolarizations in Patients with Acute Brain Injury: An Online Microdialysis Study

(2010) Delphine Feuerstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clinical Relevance of Cortical Spreading Depression in Neurological Disorders: Migraine, Malignant Stroke, Subarachnoid and Intracranial Hemorrhage, and Traumatic Brain Injury

(2010) Martin Lauritzen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential effects of pro- and anti-inflammatory cytokines alone or in combinations on the metabolic profile of astrocytes

(2010) Mireille Bélanger et al.   JOURNAL OF NEUROCHEMISTRY

Activation of Meningeal Nociceptors by Cortical Spreading Depression: Implications for Migraine with Aura

(2010) X. Zhang et al.   JOURNAL OF NEUROSCIENCE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Ciliary Neurotrophic Factor Protects Striatal Neurons against Excitotoxicity by Enhancing Glial Glutamate Uptake

(2010) Corinne Beurrier et al.   PLoS One

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Cortical Spreading Depression—New Insights and Persistent Questions

(2009) A Charles et al.   CEPHALALGIA

Molecular genetics of migraine

(2009) Boukje de Vries et al.   HUMAN GENETICS

Persistent Increase in Oxygen Consumption and Impaired Neurovascular Coupling after Spreading Depression in Rat Neocortex

(2009) Henning Piilgaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Transgenic Inhibition of Astroglial NF- B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

(2009) R. Brambilla et al.   JOURNAL OF IMMUNOLOGY

Tripartite synapses: Roles for astrocytic purines in the control of synaptic physiology and behavior

(2009) Michael M. Halassa et al.   NEUROPHARMACOLOGY

Preliminary Evidence That Ketamine Inhibits Spreading Depolarizations in Acute Human Brain Injury

(2009) Oliver W. Sakowitz et al.   STROKE

Real-time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices andin vivorevealed by two-photon microscopy

(2008) W. Christopher Risher et al.   GLIA

Metabolic Challenge to Glia Activates an Adenosine-Mediated Safety Mechanism that Promotes Neuronal Survival by Delaying the Onset of Spreading Depression Waves

(2008) Santiago Canals et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Persisting Depletion of Brain Glucose following Cortical Spreading Depression, despite Apparent Hyperaemia: Evidence for Risk of an Adverse Effect of Leão's Spreading Depression

(2008) Parastoo Hashemi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Loss of Astrocytic Domain Organization in the Epileptic Brain

(2008) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Targeted Activation of Astrocytes: A Potential Neuroprotective Strategy

(2008) Carole Escartin et al.   MOLECULAR NEUROBIOLOGY

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE

Mechanisms involved in the cerebrovascular dilator effects of cortical spreading depression

(2008) D BUSIJA et al.   PROGRESS IN NEUROBIOLOGY

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE

Mechanisms of glutamate release from astrocytes

(2007) Erik B. Malarkey et al.   NEUROCHEMISTRY INTERNATIONAL