Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation
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Title
Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation
Authors
Keywords
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Journal
Frontiers in Cellular Neuroscience
Volume 14, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-12-21
DOI
10.3389/fncel.2020.592005
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Note: Only part of the references are listed.- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
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- (2019) Fang Yu et al. Micromachines
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- (2019) Cara L. Croft et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2019) Olivia Sheppard et al. Journal of Neuroinflammation
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- (2019) Hansruedi Mathys et al. NATURE
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- (2019) Ilya Korsunsky et al. NATURE METHODS
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- (2019) Cai-Yun Liu et al. Frontiers in Cellular Neuroscience
- Organotypic brain slice cultures to model neurodegenerative proteinopathies
- (2019) C. L. Croft et al. Molecular Neurodegeneration
- Synaptic Pruning by Microglia in Epilepsy
- (2019) Megumi Andoh et al. Journal of Clinical Medicine
- Genetics of Alzheimer’s disease: where we are, and where we are going
- (2019) Céline Bellenguez et al. CURRENT OPINION IN NEUROBIOLOGY
- Elevated expression of granulocyte-macrophage colony-stimulating factor receptor in multiple sclerosis lesions
- (2018) Jaime Imitola et al. JOURNAL OF NEUROIMMUNOLOGY
- Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
- (2018) Daniela M. Magalhães et al. Journal of Neuroinflammation
- Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model
- (2018) Seon-Ah Chong et al. Neurotherapeutics
- A transcriptomic atlas of aged human microglia
- (2018) Marta Olah et al. Nature Communications
- Brain Cell Type Specific Gene Expression and Co-expression Network Architectures
- (2018) Andrew T. McKenzie et al. Scientific Reports
- Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
- (2018) Brad A. Friedman et al. Cell Reports
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- (2018) Sigrid A. Langhans Frontiers in Pharmacology
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- (2018) Srikant Rangaraju et al. Frontiers in Immunology
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- (2018) Amanda R. Burmeister et al. Frontiers in Cellular Neuroscience
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- (2017) Nizar M. Yousif et al. GLIA
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
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- (2017) Debbie A.E. Hendrickx et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2017) Soraya Wilke Saliba et al. Journal of Neuroinflammation
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
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- (2017) Han Gao et al. Cell Reports
- Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s
- (2017) Harsharan S. Bhatia et al. Scientific Reports
- Microglia replenished OHSC: A culture system to studyin vivolike adult microglia
- (2016) Annette Masuch et al. GLIA
- Microglia development follows a stepwise program to regulate brain homeostasis
- (2016) O. Matcovitch-Natan et al. SCIENCE
- Persistent Gliosis Interferes with Neurogenesis in Organotypic Hippocampal Slice Cultures
- (2016) Johannes Gerlach et al. Frontiers in Cellular Neuroscience
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- (2015) Joseph A. Lutz et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
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- (2015) Ryusuke Koshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2015) Daphne Y. S. Vogel et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2015) Jeney Ramírez-Sánchez et al. NEUROCHEMISTRY INTERNATIONAL
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- (2015) Ismini E. Papageorgiou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Olumayokun A. Olajide et al. MOLECULAR NUTRITION & FOOD RESEARCH
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- (2009) Richard A Hawkins AMERICAN JOURNAL OF CLINICAL NUTRITION
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
- (2009) Eran Eden et al. BMC BIOINFORMATICS
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- (2009) Corinne Benakis et al. BRAIN BEHAVIOR AND IMMUNITY
- Delayed treatments for stroke influence neuronal death in rat organotypic slice cultures subjected to oxygen glucose deprivation
- (2009) A.A. Hall et al. NEUROSCIENCE
- Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
- (2009) Laura Lossi et al. PROGRESS IN NEUROBIOLOGY
- The Immunological Genome Project: networks of gene expression in immune cells
- (2008) Tracy S P Heng et al. NATURE IMMUNOLOGY
- Lipopolysaccharide preconditioning induces protection against lipopolysaccharide-induced neurotoxicity in organotypic midbrain slice culture
- (2008) Ye Ding et al. Neuroscience Bulletin
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