Trypanosomatid Flagellar Pocket from Structure to Function

Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly

(2020) Moara Lemos et al.   Parasites & Vectors

Maintenance of hook complex integrity and centrin arm assembly facilitates flagellum inheritance in Trypanosoma brucei

(2020) Kieu T. M. Pham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basal Body Protein TbSAF1 Is Required for Microtubule Quartet Anchorage to the Basal Bodies in Trypanosoma brucei

(2020) Xiaoduo Dong et al.   mBio

Leishmaniaflagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host

(2019) Jack D. Sunter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BOH1 cooperates with Polo-like kinase to regulate flagellum inheritance and cytokinesis initiation in Trypanosoma brucei

(2019) Kieu T. M. Pham et al.   JOURNAL OF CELL SCIENCE

Coordination of the Cell Cycle in Trypanosomes

(2019) Richard J. Wheeler et al.   Annual Review of Microbiology

Lysosome assembly and disassembly changes endocytosis rate through the Leishmania cell cycle

(2019) Ziyin Wang et al.   MicrobiologyOpen

Evolutionary origins and specialisation of membrane transport

(2018) Joel B Dacks et al.   CURRENT OPINION IN CELL BIOLOGY

Flagellum inheritance inTrypanosoma bruceirequires a kinetoplastid-specific protein phosphatase

(2018) Qing Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of TOEFAZ1-interacting proteins reveals key regulators of Trypanosoma brucei cytokinesis

(2018) Nicholas A. Hilton et al.   MOLECULAR MICROBIOLOGY

Faithful chromosome segregation in Trypanosoma brucei requires a cohort of divergent spindle-associated proteins with distinct functions

(2018) Qing Zhou et al.   NUCLEIC ACIDS RESEARCH

Evolution of protein trafficking in kinetoplastid parasites: complexity and pathogenesis

(2018) Divya Venkatesh et al.   TRAFFIC

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing

(2018) Federico Rojas et al.   CELL

Chagas disease in Europe: A review for the internist in the globalized world

(2017) Spinello Antinori et al.   European Journal of Internal Medicine

The Trypanosoma brucei Tb Hrg protein is a heme transporter involved in the regulation of stage-specific morphological transitions

(2017) Eva Horáková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of the endomembrane systems of trypanosomatids – conservation and specialisation

(2017) Divya Venkatesh et al.   JOURNAL OF CELL SCIENCE

Human African trypanosomiasis

(2017) Philippe Büscher et al.   LANCET

TbSmee1 regulates hook complex morphology and the rate of flagellar pocket uptake in Trypanosoma brucei

(2017) Jenna A. Perry et al.   MOLECULAR MICROBIOLOGY

Extensive flagellar remodeling during the complex life cycle ofParatrypanosoma, an early-branching trypanosomatid

(2017) Tomáš Skalický et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei

(2017) Anna Albisetti et al.   PLoS Pathogens

The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis

(2017) Cordula M. Boehm et al.   PLoS Pathogens

Flagellar pocket restructuring through theLeishmanialife cycle involves a discrete flagellum attachment zone

(2016) Richard J. Wheeler et al.   JOURNAL OF CELL SCIENCE

The cytostome–cytopharynx complex ofTrypanosoma cruziepimastigotes disassembles during cell division

(2016) Carolina de L. Alcantara et al.   JOURNAL OF CELL SCIENCE

The endocytic activity of the flagellar pocket inTrypanosoma bruceiis regulated by an adjacent phosphatidylinositol phosphate kinase

(2016) Lars Demmel et al.   JOURNAL OF CELL SCIENCE

Loss of the cytostome-cytopharynx and endocytic ability are late events in Trypanosoma cruzi metacyclogenesis

(2016) Juliana C. Vidal et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Flagellum Attachment Zone: ‘The Cellular Ruler’ of Trypanosome Morphology

(2016) Jack D. Sunter et al.   TRENDS IN PARASITOLOGY

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake

(2016) Marcelo L. Merli et al.   PLoS Neglected Tropical Diseases

Species-Specific Adaptations of Trypanosome Morphology and Motility to the Mammalian Host

(2016) Joel L. Bargul et al.   PLoS Pathogens

The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein—TbBILBO1

(2016) Doranda Perdomo et al.   Cells

Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis

(2016) Sébastien Brosson et al.   PLoS One

Conservation and divergence within the clathrin interactome of Trypanosoma cruzi

(2016) Ligia Cristina Kalb et al.   Scientific Reports

A MORN Repeat Protein Facilitates Protein Entry into the Flagellar Pocket of Trypanosoma brucei

(2015) Brooke Morriswood et al.   EUKARYOTIC CELL

Form, Fabric, and Function of a Flagellum-Associated Cytoskeletal Structure

(2015) Brooke Morriswood   Cells

The three-dimensional structure of the cytostome-cytopharynx complex ofTrypanosoma cruziepimastigotes

(2014) Carolina L. Alcantara et al.   JOURNAL OF CELL SCIENCE

Life and times: synthesis, trafficking, and evolution of VSG

(2014) Paul T. Manna et al.   TRENDS IN PARASITOLOGY

The tubulin cofactor C family member TBCCD1 orchestrates cytoskeletal filament formation

(2013) J. Andre et al.   JOURNAL OF CELL SCIENCE

An analogue-sensitive approach identifies basal body rotation and flagellum attachment zone elongation as key functions of PLK in Trypanosoma brucei

(2013) Ana Lozano-Núñez et al.   MOLECULAR BIOLOGY OF THE CELL

Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids

(2013) Paul T. Manna et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Expression and cellular trafficking of GP82 and GP90 glycoproteins during Trypanosoma cruzi metacyclogenesis

(2013) Ethel Bayer-Santos et al.   Parasites & Vectors

Make It, Take It, or Leave It: Heme Metabolism of Parasites

(2013) Luděk Kořený et al.   PLoS Pathogens

Morphology of the Trypanosome Bilobe, a Novel Cytoskeletal Structure

(2012) Heather J. Esson et al.   EUKARYOTIC CELL

Novel Bilobe Components in Trypanosoma brucei Identified Using Proximity-Dependent Biotinylation

(2012) Brooke Morriswood et al.   EUKARYOTIC CELL

Biochemical Characterization of the Bi-lobe Reveals a Continuous Structural Network Linking the Bi-lobe to Other Single-copied Organelles inTrypanosoma brucei

(2012) Ladan Gheiratmand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei

(2012) Johanna L. Höög et al.   JOURNAL OF STRUCTURAL BIOLOGY

Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

(2012) Chau Huynh et al.   PLoS Pathogens

Morphological Events during the Cell Cycle of Leishmania major

(2011) Audrey Ambit et al.   EUKARYOTIC CELL

Exocytosis and protein secretion in Trypanosoma

(2010) Anne Geiger et al.   BMC MICROBIOLOGY

Trafficking activity of myosin XXI is required in assembly of Leishmania flagellum

(2010) S. S. Katta et al.   JOURNAL OF CELL SCIENCE

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

(2010) S. Lacomble et al.   JOURNAL OF CELL SCIENCE

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology

(2010) Richard J. Wheeler et al.   MOLECULAR MICROBIOLOGY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Attachment of flagellum to the cell body is important to the kinetics of transferrin uptake by Trypanosoma cruzi

(2010) Gustavo Miranda Rocha et al.   PARASITOLOGY INTERNATIONAL

A Comparative Proteomic Analysis Reveals a New Bi-Lobe Protein Required for Bi-Lobe Duplication and Cell Division in Trypanosoma brucei

(2010) Qing Zhou et al.   PLoS One

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography

(2009) S. Lacomble et al.   JOURNAL OF CELL SCIENCE

Structural organization of Trypanosoma cruzi

(2009) Wanderley de Souza   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The bilobe structure of Trypanosoma brucei contains a MORN-repeat protein

(2009) Brooke Morriswood et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The trypanosome flagellar pocket

(2009) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes

(2009) C. Gadelha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electron microscopy and cytochemistry analysis of the endocytic pathway of pathogenic protozoa

(2009) Wanderley de Souza et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation

(2008) A. Barquilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Haptoglobin-Hemoglobin Receptor Conveys Innate Immunity to Trypanosoma brucei in Humans

(2008) B. Vanhollebeke et al.   SCIENCE

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

(2008) Mélanie Bonhivers et al.   PLOS BIOLOGY

A contractile vacuole complex is involved in osmoregulation in Trypanosoma cruzi

(2007) Peter Rohloff et al.   EXPERIMENTAL PARASITOLOGY