The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis

A paneukaryotic genomic analysis of the small GTPase RABL2 underscores the significance of recurrent gene loss in eukaryote evolution

(2016) Marek Eliáš et al.   Biology Direct

Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia

(2016) Anthony J. Szempruch et al.   CELL

Exploiting the Achilles’ heel of membrane trafficking in trypanosomes

(2016) Martin Zoltner et al.   CURRENT OPINION IN MICROBIOLOGY

Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania

(2016) Pavel Flegontov et al.   Scientific Reports

The Exocyst Subunit Sec6 Interacts with Assembled Exocytic SNARE Complexes

(2015) Michelle L. Dubuke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tracking individual secretory vesicles during exocytosis reveals an ordered and regulated process

(2015) Kirk W. Donovan et al.   JOURNAL OF CELL BIOLOGY

Architecture of a Host–Parasite Interface: Complex Targeting Mechanisms Revealed Through Proteomics

(2015) Catarina Gadelha et al.   MOLECULAR & CELLULAR PROTEOMICS

Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

(2015) Margaret R Heider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

(2015) Margaret R Heider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

(2015) Martin Zoltner et al.   PLoS Pathogens

Tetrahymena thermophila: A divergent perspective on membrane traffic

(2014) Joseph S. Briguglio et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

The role of Sec3p in secretory vesicle targeting and exocyst complex assembly

(2014) Guangzuo Luo et al.   MOLECULAR BIOLOGY OF THE CELL

Life and times: synthesis, trafficking, and evolution of VSG

(2014) Paul T. Manna et al.   TRENDS IN PARASITOLOGY

The exocyst at the interface between cytoskeleton and membranes in eukaryotic cells

(2014) Lukáš Synek et al.   Frontiers in Plant Science

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

(2013) Pedro Monteiro et al.   JOURNAL OF CELL BIOLOGY

The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p

(2013) David Shen et al.   JOURNAL OF CELL BIOLOGY

Robust polarity establishment occurs via an endocytosis-based cortical corralling mechanism

(2013) Mini Jose et al.   JOURNAL OF CELL BIOLOGY

Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion

(2013) Felix Rivera-Molina et al.   JOURNAL OF CELL BIOLOGY

Syntaxin 16 is a master recruitment factor for cytokinesis

(2013) Hélia Neto et al.   MOLECULAR BIOLOGY OF THE CELL

Comparative Genomic Analysis of Multi-Subunit Tethering Complexes Demonstrates an Ancient Pan-Eukaryotic Complement and Sculpting in Apicomplexa

(2013) Christen M. Klinger et al.   PLoS One

Proteomic Analysis of Clathrin Interactions in Trypanosomes Reveals Dynamic Evolution of Endocytosis

(2013) Vincent O. Adung'a et al.   TRAFFIC

Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy

(2013) Sam Alsford et al.   TRENDS IN PARASITOLOGY

Non-uniform membrane diffusion enables steady-state cell polarization via vesicular trafficking

(2013) Brian D. Slaughter et al.   Nature Communications

Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry

(2012) Kapila Gunasekera et al.   BMC GENOMICS

Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione

(2012) Akhilesh Kumar et al.   EMBO REPORTS

Evidence for Recycling of Invariant Surface Transmembrane Domain Proteins in African Trypanosomes

(2012) V. Lila Koumandou et al.   EUKARYOTIC CELL

Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases

(2012) M. Elias et al.   JOURNAL OF CELL SCIENCE

Cdk1-dependent control of membrane-trafficking dynamics

(2012) Derek McCusker et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei

(2012) Paula MacGregor et al.   NUCLEIC ACIDS RESEARCH

Comparative SILAC Proteomic Analysis of Trypanosoma brucei Bloodstream and Procyclic Lifecycle Stages

(2012) Michael D. Urbaniak et al.   PLoS One

Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo

(2011) Peng Jin et al.   DEVELOPMENTAL CELL

Rab11 Function in Trypanosoma brucei: Identification of Conserved and Novel Interaction Partners

(2011) Carme Gabernet-Castello et al.   EUKARYOTIC CELL

Regulation of exocytosis by the exocyst subunit Sec6 and the SM protein Sec1

(2011) Francesca Morgera et al.   MOLECULAR BIOLOGY OF THE CELL

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Correction: A Novel Rho-Like Protein TbRHP Is Involved in Spindle Formation and Mitosis in Trypanosomes

(2011) Kanwal Abbasi et al.   PLoS One

Tethering Factors as Organizers of Intracellular Vesicular Traffic

(2010) I-Mei Yu et al.   Annual Review of Cell and Developmental Biology

Rab protein evolution and the history of the eukaryotic endomembrane system

(2010) Andrew Brighouse et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Actin dynamics and endocytosis in yeast and mammals

(2010) Brian J Galletta et al.   CURRENT OPINION IN BIOTECHNOLOGY

Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes

(2010) N. Vasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi

(2009) Nickias Kienle et al.   BMC EVOLUTIONARY BIOLOGY

Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

(2009) Jeffrey A. DeGrasse et al.   MOLECULAR & CELLULAR PROTEOMICS

The Exo70 Subunit of the Exocyst Is an Effector for Both Cdc42 and Rho3 Function in Polarized Exocytosis

(2009) Hao Wu et al.   MOLECULAR BIOLOGY OF THE CELL

A surface transporter family conveys the trypanosome differentiation signal

(2009) Samuel Dean et al.   NATURE

TriTrypDB: a functional genomic resource for the Trypanosomatidae

(2009) Martin Aslett et al.   NUCLEIC ACIDS RESEARCH

Conservation of Helical Bundle Structure between the Exocyst Subunits

(2009) Nicole J. Croteau et al.   PLoS One

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes

(2009) C. Gadelha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PredGPI: a GPI-anchor predictor

(2008) Andrea Pierleoni et al.   BMC BIOINFORMATICS

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

(2008) Sam Alsford et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Evolution of the Multivesicular Body ESCRT Machinery; Retention Across the Eukaryotic Lineage

(2008) Ka Fai Leung et al.   TRAFFIC

Ubiquitylation is Required for Degradation of Transmembrane Surface Proteins in Trypanosomes

(2008) Wei-Lian Chung et al.   TRAFFIC

The ghost in the machine: small GTPases as spatial regulators of exocytosis

(2008) Hao Wu et al.   TRENDS IN CELL BIOLOGY