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Title
Combining Antivirals and Immunomodulators to Fight COVID-19
Authors
Keywords
COVID-19, SARS-CoV-2, antiviral molecules, immunomodulators, IFNα/β, cytokine storm
Journal
TRENDS IN IMMUNOLOGY
Volume 42, Issue 1, Pages 31-44
Publisher
Elsevier BV
Online
2020-11-13
DOI
10.1016/j.it.2020.11.003
References
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Note: Only part of the references are listed.- Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
- (2020) Peter Richardson et al. LANCET
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- (2020) Clark D Russell et al. LANCET
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- (2020) Xingyue Ji et al. MEDICINAL RESEARCH REVIEWS
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- (2020) Guangdi Li et al. NATURE REVIEWS DRUG DISCOVERY
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- (2020) Marion V Guerin et al. eLife
- Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection
- (2020) Daniel M. Muema et al. BMC Medicine
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
- (2020) Evangelos J. Giamarellos-Bourboulis et al. Cell Host & Microbe
- Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State
- (2020) Eli S. Rosenberg et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cytokine release syndrome in severe COVID-19
- (2020) John B. Moore et al. SCIENCE
- Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series
- (2020) Negar Mohtadi et al. VIROLOGY
- Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France
- (2020) Matthieu Million et al. Travel Medicine and Infectious Disease
- Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19
- (2020) Caleb P. Skipper et al. ANNALS OF INTERNAL MEDICINE
- Efficacy and safety of interferon β-1a in treatment of severe COVID-19: A randomized clinical trial
- (2020) Effat Davoudi-Monfared et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
- (2020) Ashleigh Shannon et al. ANTIVIRAL RESEARCH
- Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)
- (2020) Chiara Agrati et al. CELL DEATH AND DIFFERENTIATION
- Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)
- (2020) W. Joost Wiersinga et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19
- (2020) Carlo Perricone et al. JOURNAL OF AUTOIMMUNITY
- Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis
- (2020) Julien Carvelli et al. NATURE
- Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates
- (2020) Pauline Maisonnasse et al. NATURE
- A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir
- (2020) Chengyuan Liang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Autoantibodies against type I IFNs in patients with life-threatening COVID-19
- (2020) Paul Bastard et al. SCIENCE
- Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
- (2020) Ashleigh Shannon et al. Nature Communications
- 1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB
- (2019) Ke-Gang Linghu et al. Frontiers in Pharmacology
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- (2019) I-Yin Chen et al. Frontiers in Microbiology
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- (2019) Marion V. Guerin et al. Nature Communications
- The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation
- (2018) Gonzalo J. Martínez et al. ATHEROSCLEROSIS
- Highlights for Dengue Immunopathogenesis: Antibody-Dependent Enhancement, Cytokine Storm, and Beyond
- (2018) Diogo Kuczera et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
- (2018) Margherita Norelli et al. NATURE MEDICINE
- The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination
- (2017) Yong Hu et al. JOURNAL OF VIROLOGY
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- (2017) Yousuke FURUTA et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Immune-mediated cytokine storm and its role in severe dengue
- (2017) Anon Srikiatkhachorn et al. Seminars in Immunopathology
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- (2017) Diede Oudshoorn et al. mBio
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- (2016) Rudragouda Channappanavar et al. Cell Host & Microbe
- 1,8-Cineole potentiates IRF3-mediated antiviral response in human stem cells and in an ex vivo model of rhinosinusitis
- (2016) J. Muller et al. CLINICAL SCIENCE
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- (2016) Yun Li et al. INFLAMMATION
- TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
- (2016) Fan Zhang et al. Oncotarget
- Structure, Function, and Evolution of Coronavirus Spike Proteins
- (2016) Fang Li Annual Review of Virology
- Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus
- (2015) Kai-Wen Cheng et al. ANTIVIRAL RESEARCH
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- (2015) Rathinam Vasanthakumar et al. CYTOKINE
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- Bats as ‘special’ reservoirs for emerging zoonotic pathogens
- (2015) Cara E. Brook et al. TRENDS IN MICROBIOLOGY
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- (2015) Jose L. Nieto-Torres et al. VIROLOGY
- Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets
- (2015) Yang Yang et al. Scientific Reports
- Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study
- (2014) Jaffar A. Al-Tawfiq et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
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- The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus
- (2013) P. S. Akhavan et al. JOURNAL OF RHEUMATOLOGY
- Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus
- (2013) F. Zielecki et al. JOURNAL OF VIROLOGY
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
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- (2012) J. R. Tisoncik et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Correlation between TGF-β1 expression and proteomic profiling induced by severe acute respiratory syndrome coronavirus papain-like protease
- (2012) Shih-Wen Li et al. PROTEOMICS
- SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon
- (2012) Allison L Totura et al. Current Opinion in Virology
- Pegylated-interferon-α2ain clinical practice: how to manage patients suffering from side effects
- (2011) Vincenza Calvaruso et al. Expert Opinion On Drug Safety
- Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses
- (2010) Roberto Lande et al. Annals of the New York Academy of Sciences
- Recent Advances in Targeting Viral Proteases for the Discovery of Novel Antivirals
- (2010) Holger Steuber et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques
- (2010) L. D. Harris et al. JOURNAL OF VIROLOGY
- A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults
- (2010) Vianney Tricou et al. PLoS Neglected Tropical Diseases
- Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates
- (2010) Saskia L. Smits et al. PLoS Pathogens
- Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex
- (2009) Kam-Leung Siu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection
- (2009) A. N. Freiberg et al. JOURNAL OF GENERAL VIROLOGY
- Coronaviruses post-SARS: update on replication and pathogenesis
- (2009) Stanley Perlman et al. NATURE REVIEWS MICROBIOLOGY
- On Chikungunya Acute Infection and Chloroquine Treatment
- (2008) Xavier De Lamballerie et al. VECTOR-BORNE AND ZOONOTIC DISEASES
- SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
- (2008) Kèvin Knoops et al. PLOS BIOLOGY
- Respiratory Syncytial Virus Infection in Patients with Hematological Diseases: Single-Center Study and Review of the Literature
- (2007) N. Khanna et al. CLINICAL INFECTIOUS DISEASES
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