Role of GTPases in Driving Mitoribosome Assembly

Molecular Evolutionary Genetics Analysis (MEGA) for macOS

(2020) Glen Stecher et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis

(2020) Mateusz Jaskolowski et al.   MOLECULAR CELL

A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly

(2020) Michela Di Nottia et al.   NEUROBIOLOGY OF DISEASE

RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases

(2020) Aurelio Reyes et al.   PLoS Genetics

The Diseased Mitoribosome

(2020) Alberto Ferrari et al.   FEBS LETTERS

Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes

(2020) Elena Lavdovskaia et al.   NUCLEIC ACIDS RESEARCH

Novel role of mitochondrial GTPases 1 in pathological cardiac hypertrophy

(2019) Dachun Xu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy

(2019) Enrico Bugiardini et al.   HUMAN MOLECULAR GENETICS

Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate

(2019) Amal Seffouh et al.   NUCLEIC ACIDS RESEARCH

MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

(2019) Jakob D. Busch et al.   Cell Reports

The Impact of the Stringent Response on TRAFAC GTPases and Prokaryotic Ribosome Assembly

(2019) Bennison et al.   Cells

Bi-allelic Mutations in the Mitochondrial Ribosomal Protein MRPS2 Cause Sensorineural Hearing Loss, Hypoglycemia, and Multiple OXPHOS Complex Deficiencies

(2018) Thatjana Gardeitchik et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency

(2018) Anlu Chen et al.   HUMAN MOLECULAR GENETICS

The universally conserved GTPase HflX is an RNA helicase that restores heat-damagedEscherichia coliribosomes

(2018) Sandip Dey et al.   JOURNAL OF CELL BIOLOGY

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

Kinetics and Mechanism of Mammalian Mitochondrial Ribosome Assembly

(2018) Daniel F. Bogenhagen et al.   Cell Reports

The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis

(2018) Elena Lavdovskaia et al.   NUCLEIC ACIDS RESEARCH

Structural modules of the stress-induced protein HflX: an outlook on its evolution and biological role

(2018) Krishnamoorthi Srinivasan et al.   CURRENT GENETICS

A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement

(2018) Christopher B Jackson et al.   HUMAN MOLECULAR GENETICS

A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome

(2017) Iliana A. Chatzispyrou et al.   HUMAN MOLECULAR GENETICS

The FASTK family of proteins: emerging regulators of mitochondrial RNA biology

(2017) Alexis A. Jourdain et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial ribosomes in cancer

(2017) Hyun-Jung Kim et al.   SEMINARS IN CANCER BIOLOGY

Structure and Function of the Mitochondrial Ribosome

(2016) Basil J. Greber et al.   Annual Review of Biochemistry

CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels

(2016) Karolina Szczepanowska et al.   EMBO JOURNAL

Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer

(2016) Hong-Jian Jin et al.   Oncotarget

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

(2016) Oliver Rackham et al.   Cell Reports

A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies

(2016) Masakazu Kohda et al.   PLoS Genetics

Mitochondrial ribosome assembly in health and disease

(2015) Dasmanthie De Silva et al.   CELL CYCLE

Meta-analysis of differentially expressed genes in ankylosing spondylitis

(2015) Y.H. Lee et al.   GENETICS AND MOLECULAR RESEARCH

Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia

(2015) Minal J. Menezes et al.   HUMAN MOLECULAR GENETICS

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

(2015) Yanqing Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MRPL44 mutations cause a slowly progressive multisystem disease with childhood-onset hypertrophic cardiomyopathy

(2015) Felix Distelmaier et al.   NEUROGENETICS

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

(2015) Yanqing Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mitochondriolus: assembling mitoribosomes

(2015) Antoni Barrientos   Oncotarget

The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly

(2015) Ya-Ting Tu et al.   Cell Reports

Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis

(2015) Hana Antonicka et al.   Cell Reports

Initial Steps in RNA Processing and Ribosome Assembly Occur at Mitochondrial DNA Nucleoids

(2014) Daniel F. Bogenhagen et al.   Cell Metabolism

Assignment of 2′-O-Methyltransferases to Modification Sites on the Mammalian Mitochondrial Large Subunit 16 S Ribosomal RNA (rRNA)

(2014) Ken-Wing Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome

(2014) Joanna Rorbach et al.   MOLECULAR BIOLOGY OF THE CELL

The complete structure of the large subunit of the mammalian mitochondrial ribosome

(2014) Basil J. Greber et al.   NATURE

NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

(2014) Natalie Al-Furoukh et al.   PLoS One

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase

(2014) Boya Feng et al.   PLOS BIOLOGY

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

(2014) Metodi Dimitrov Metodiev et al.   PLoS Genetics

Perrault Syndrome Is Caused by Recessive Mutations in CLPP, Encoding a Mitochondrial ATP-Dependent Chambered Protease

(2013) Emma M. Jenkinson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency

(2013) Valérie Serre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules

(2013) Alexis A. Jourdain et al.   Cell Metabolism

The DEAD Box Protein Mrh4 Functions in the Assembly of the Mitochondrial Large Ribosomal Subunit

(2013) Dasmanthie De Silva et al.   Cell Metabolism

The Mitochondrial RNA-Binding Protein GRSF1 Localizes to RNA Granules and Is Required for Posttranscriptional Mitochondrial Gene Expression

(2013) Hana Antonicka et al.   Cell Metabolism

GTPases involved in bacterial ribosome maturation

(2013) Simon Goto et al.   JOURNAL OF BIOCHEMISTRY

Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy

(2013) Christopher J Carroll et al.   JOURNAL OF MEDICAL GENETICS

Functional domains of the 50S subunit mature late in the assembly process

(2013) A. Jomaa et al.   NUCLEIC ACIDS RESEARCH

Mutational analysis of the ribosome assembly GTPase RbgA provides insight into ribosome interaction and ribosome-stimulated GTPase activation

(2013) Megha Gulati et al.   NUCLEIC ACIDS RESEARCH

Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes

(2013) Tetsuya Kotani et al.   NUCLEIC ACIDS RESEARCH

Biochemical Characterization of Ribosome Assembly GTPase RbgA inBacillus subtilis

(2012) David Achila et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Putative GTPase Encoded byMTG3Functions in a Novel Pathway for Regulating Assembly of the Small Subunit of Yeast Mitochondrial Ribosomes

(2012) Marie-Françoise Paul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human C4orf14 interacts with the mitochondrial nucleoid and is involved in the biogenesis of the small mitochondrial ribosomal subunit

(2012) J. He et al.   NUCLEIC ACIDS RESEARCH

De novo deletion of chromosome 20q13.33 in a patient with tracheo-esophageal fistula, cardiac defects and genitourinary anomalies implicates GTPBP5 as a candidate gene

(2011) Benjamin D. Solomon et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Exome sequencing identifies MRPL3 mutation in mitochondrial cardiomyopathy

(2011) Louise Galmiche et al.   HUMAN MUTATION

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA

(2011) C. Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit

(2010) Sven Dennerlein et al.   BIOCHEMICAL JOURNAL

Mutation in mitochondrial ribosomal protein MRPS22 leads to Cornelia de Lange-like phenotype, brain abnormalities and hypertrophic cardiomyopathy

(2010) Paulien Smits et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

NOA1 is an essential GTPase required for mitochondrial protein synthesis

(2010) Mateusz Kolanczyk et al.   MOLECULAR BIOLOGY OF THE CELL

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

(2010) Takeshi Uchiumi et al.   NUCLEIC ACIDS RESEARCH

Role of GTPases in Bacterial Ribosome Assembly

(2009) Robert A. Britton   Annual Review of Microbiology

Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly

(2009) Baskaran Anand et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome

(2009) Metodi D. Metodiev et al.   Cell Metabolism

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

Structure of ERA in complex with the 3' end of 16S rRNA: Implications for ribosome biogenesis

(2009) C. Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

hNOA1 Interacts with Complex I and DAP3 and Regulates Mitochondrial Respiration and Apoptosis

(2008) Tingdong Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY