Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes

Rescuing stalled mammalian mitoribosomes – what can we learn from bacteria?

(2020) Shreya Ahana Ayyub et al.   JOURNAL OF CELL SCIENCE

Structural insights into unique features of the human mitochondrial ribosome recycling

(2019) Ravi K. Koripella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

(2019) Jakob D. Busch et al.   Cell Reports

Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance

(2019) Paulami Rudra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The universally conserved GTPase HflX is an RNA helicase that restores heat-damagedEscherichia coliribosomes

(2018) Sandip Dey et al.   JOURNAL OF CELL BIOLOGY

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis

(2018) Elena Lavdovskaia et al.   NUCLEIC ACIDS RESEARCH

Structural modules of the stress-induced protein HflX: an outlook on its evolution and biological role

(2018) Krishnamoorthi Srinivasan et al.   CURRENT GENETICS

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance

(2018) Mélodie Duval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional Switch between Frameshifting Regimes upon Translation of dnaX mRNA

(2017) Neva Caliskan et al.   MOLECULAR CELL

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Disassembly of theStaphylococcus aureushibernating 100S ribosome by an evolutionarily conserved GTPase

(2017) Arnab Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Mammalian Mitochondrial Gene Expression: Recent Advances

(2017) Sarah F. Pearce et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

Structure and Function of the Mitochondrial Ribosome

(2016) Basil J. Greber et al.   Annual Review of Biochemistry

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

(2016) Ricarda Richter-Dennerlein et al.   CELL

NSUN3 and ABH1 modify the wobble position of mt‐tRNAMetto expand codon recognition in mitochondrial translation

(2016) Sara Haag et al.   EMBO JOURNAL

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosome

(2016) Mackenzie L. Coatham et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial ribosome assembly in health and disease

(2015) Dasmanthie De Silva et al.   CELL CYCLE

Integrating mitochondrial translation into the cellular context

(2015) Ricarda Richter-Dennerlein et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

(2015) Yanqing Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

(2015) Yanqing Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly

(2015) Sven Dennerlein et al.   Cell Reports

MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome

(2014) Joanna Rorbach et al.   MOLECULAR BIOLOGY OF THE CELL

The complete structure of the large subunit of the mammalian mitochondrial ribosome

(2014) Basil J. Greber et al.   NATURE

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

(2014) Shiori Akabane et al.   PLoS Genetics

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

(2014) Metodi Dimitrov Metodiev et al.   PLoS Genetics

Overcoming stalled translation in human mitochondria

(2014) Maria T. Wesolowska et al.   Frontiers in Microbiology

Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes

(2013) Tetsuya Kotani et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of a hitherto unknown nucleotide-binding domain and an intricate interdomain regulation in HflX-a ribosome binding GTPase

(2013) Nikhil Jain et al.   NUCLEIC ACIDS RESEARCH

MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation

(2012) David U. Mick et al.   CELL

C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation

(2012) Bas F. J. Wanschers et al.   NUCLEIC ACIDS RESEARCH

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome

(2012) Joanna Rorbach et al.   NUCLEIC ACIDS RESEARCH

Human C4orf14 interacts with the mitochondrial nucleoid and is involved in the biogenesis of the small mitochondrial ribosomal subunit

(2012) J. He et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

(2012) M. G. Gagnon et al.   SCIENCE

Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways

(2011) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit

(2010) Sven Dennerlein et al.   BIOCHEMICAL JOURNAL

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Functional study on GTP hydrolysis by the GTP-binding protein from Sulfolobus solfataricus, a member of the HflX family

(2010) Bo Huang et al.   JOURNAL OF BIOCHEMISTRY

NOA1 is an essential GTPase required for mitochondrial protein synthesis

(2010) Mateusz Kolanczyk et al.   MOLECULAR BIOLOGY OF THE CELL

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

(2010) Takeshi Uchiumi et al.   NUCLEIC ACIDS RESEARCH

YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes

(2010) Y. Handa et al.   NUCLEIC ACIDS RESEARCH

EF-G2mt Is an Exclusive Recycling Factor in Mammalian Mitochondrial Protein Synthesis

(2009) Masafumi Tsuboi et al.   MOLECULAR CELL

E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides

(2008) Nikhil Jain et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chlamydophila pneumoniae HflX belongs to an uncharacterized family of conserved GTPases and associates with the Escherichia coli 50S large ribosomal subunit

(2008) A. Polkinghorne et al.   MICROBIOLOGY-SGM

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

The human mitochondrial ribosome recycling factor is essential for cell viability

(2008) Joanna Rorbach et al.   NUCLEIC ACIDS RESEARCH