Control of immunity by glucocorticoids in health and disease

Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood

(2020) Derek W. Cain et al.   JOURNAL OF IMMUNOLOGY

Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells

(2018) Louise M. Ince et al.   FASEB JOURNAL

Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4

(2018) Akihiro Shimba et al.   IMMUNITY

Glucocorticoid hormone treatment enhances the cytokine production of regulatory T cells by upregulation of Foxp3 expression

(2018) Emese Ugor et al.   IMMUNOBIOLOGY

066 Glucocorticoids promote intrinsic human Th17 differentiation

(2018) J. de Castro Kroner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The pathogenicity of IL-33 on steroid-resistant eosinophilic inflammation via the activation of memory-type ST2+ CD4+ T cells

(2018) Kiyoshi Hirahara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chronic Sleep Restriction Impairs the Antitumor Immune Response in Mice

(2018) Beatriz Helena Pizarro De Lorenzo et al.   NEUROIMMUNOMODULATION

Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells

(2018) Linda Quatrini et al.   NATURE IMMUNOLOGY

Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses

(2017) David Druzd et al.   IMMUNITY

Corrigendum to “Calcipotriol and betamethasone dipropionate exert additive inhibitory effects on the cytokine expression of inflammatory dendritic cell-Th17 cell axis in psoriasis” [J. Dermatol. Sci. 81 (2016) 153–164]

(2017) Paola Lovato et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells

(2017) Linda Quatrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma

(2017) Carina Klaßen et al.   JOURNAL OF IMMUNOLOGY

Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit

(2017) Yasunobu Arima et al.   eLife

Regulatory effects of dexamethasone on NK and T cell immunity

(2017) Liying Chen et al.   INFLAMMOPHARMACOLOGY

Immunopathology alters Th17 cell glucocorticoid sensitivity

(2016) J. Banuelos et al.   ALLERGY

Adrenergic control of the adaptive immune response by diurnal lymphocyte recirculation through lymph nodes

(2016) Kazuhiro Suzuki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells

(2015) Akifumi Abe et al.   JOURNAL OF IMMUNOLOGY

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

(2015) Steven W Paugh et al.   NATURE GENETICS

Glucocorticoid-resistant Th17 cells are selectively attenuated by cyclosporine A

(2015) Lauren P. Schewitz-Bowers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis

(2015) Caiyi C. Li et al.   PLOS BIOLOGY

Comprehensive Overview of the Structure and Regulation of the Glucocorticoid Receptor

(2014) Sofie Vandevyver et al.   ENDOCRINE REVIEWS

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

Circadian Clock Proteins and Immunity

(2014) Anne M. Curtis et al.   IMMUNITY

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids

(2014) Radha Ramesh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral T Cells Are the Therapeutic Targets of Glucocorticoids in Experimental Autoimmune Encephalomyelitis

(2014) S. Wust et al.   JOURNAL OF IMMUNOLOGY

An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

(2014) Julie Gibbs et al.   NATURE MEDICINE

Targeting Th17 cells in autoimmune diseases

(2014) Jianfei Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

In vivo suppression of NK cell cytotoxicity by stress and surgery: Glucocorticoids have a minor role compared to catecholamines and prostaglandins

(2013) Ella Rosenne et al.   BRAIN BEHAVIOR AND IMMUNITY

Homeostasis in Intestinal Epithelium Is Orchestrated by the Circadian Clock and Microbiota Cues Transduced by TLRs

(2013) Atish Mukherji et al.   CELL

CD4+T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection

(2013) David G. Kugler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circadian clock regulates the host response to Salmonella

(2013) M. M. Bellet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic memory type Th2 cells in allergic inflammation

(2013) Yusuke Endo et al.   TRENDS IN IMMUNOLOGY

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice

(2012) Denise Tischner et al.   JOURNAL OF AUTOIMMUNITY

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

(2012) Paul R. Mittelstadt et al.   JOURNAL OF CLINICAL INVESTIGATION

Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling

(2012) J Zhao et al.   Mucosal Immunology

Interleukin-7 receptor controls development and maturation of late stages of thymocyte subpopulations

(2012) S. Tani-ichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

(2011) Masaki Kashiwada et al.   EMBO JOURNAL

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages

(2011) Anna Kleiman et al.   FASEB JOURNAL

Glucocorticoids Sensitize the Innate Immune System through Regulation of the NLRP3 Inflammasome

(2011) John M. Busillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of Short-Term Glucocorticoid Therapy on Regulatory T Cells In Vivo

(2011) Silviu Sbiera et al.   PLoS One

Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

(2011) U. Baschant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoids enhance Th17/Th1 imbalance and signal transducer and activator of transcription 3 expression in systemic lupus erythematosus patients

(2011) Catuxa Prado et al.   RHEUMATOLOGY

Stress-Induced Glucocorticoids at the Earliest Stages of Herpes Simplex Virus-1 Infection Suppress Subsequent Antiviral Immunity, Implicating Impaired Dendritic Cell Function

(2010) Michael D. Elftman et al.   JOURNAL OF IMMUNOLOGY

Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate

(2010) R Hino et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Cortisol and epinephrine control opposing circadian rhythms in T cell subsets

(2009) S. Dimitrov et al.   BLOOD

Restraint stress modulates virus specific adaptive immunity during acute Theiler’s virus infection

(2009) Andrew J. Steelman et al.   BRAIN BEHAVIOR AND IMMUNITY

Surgical Stress-Induced Immune Cell Redistribution Profiles Predict Short-Term and Long-Term Postsurgical Recovery

(2009) Patricia H Rosenberger et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

(2009) Firdaus S. Dhabhar   NEUROIMMUNOMODULATION

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

(2009) A. Y.-L. So et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiation and maintenance of Th2 cell identity

(2008) Toshinori Nakayama et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction

(2008) Hideki Ogura et al.   IMMUNITY