Ectonucleoside triphosphate diphosphohydrolases and ecto-5′-nucleotidase in purinergic signaling: how the field developed and where we are now
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ectonucleoside triphosphate diphosphohydrolases and ecto-5′-nucleotidase in purinergic signaling: how the field developed and where we are now
Authors
Keywords
-
Journal
Purinergic Signalling
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-18
DOI
10.1007/s11302-020-09755-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- 2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes
- (2020) Sanjay Bhattarai et al. JOURNAL OF MEDICINAL CHEMISTRY
- The role of the CD39–CD73–adenosine pathway in liver disease
- (2020) Sheng Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ecto-Nucleotidases CD73 and CD39
- (2020) Jenna L. Jeffrey et al. JOURNAL OF MEDICINAL CHEMISTRY
- Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7- trifluoromethyl-thiadiazolopyrimidones Scaffold
- (2020) Saira Afzal et al. Medicinal Chemistry
- Conversion of extracellular ATP into adenosine: a master switch in renal health and disease
- (2020) Karen M. Dwyer et al. Nature Reviews Nephrology
- Structure–Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5′-Nucleotidase (CD73) Inhibitors
- (2019) Anna Junker et al. JOURNAL OF MEDICINAL CHEMISTRY
- Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
- (2019) Ivan Perrot et al. Cell Reports
- Cell type- and tissue-specific functions of ecto-5'-nucleotidase (CD73)
- (2019) Marquet Minor et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- CD73: an emerging checkpoint for cancer immunotherapy
- (2019) Siqi Chen et al. Immunotherapy
- CD39-adenosinergic axis in renal pathophysiology and therapeutics
- (2018) Bellamkonda K. Kishore et al. Purinergic Signalling
- The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets
- (2017) Bertrand Allard et al. IMMUNOLOGICAL REVIEWS
- Purinergic signaling during intestinal inflammation
- (2017) Maria Serena Longhi et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action
- (2016) James C. Geoghegan et al. mAbs
- Regulation of the T Cell Response by CD39
- (2016) Maisa C. Takenaka et al. TRENDS IN IMMUNOLOGY
- Targeting CD73 in the tumor microenvironment with MEDI9447
- (2016) Carl M. Hay et al. OncoImmunology
- Polyoxometalates—Potent and selective ecto-nucleotidase inhibitors
- (2015) Sang-Yong Lee et al. BIOCHEMICAL PHARMACOLOGY
- Insights into Ecto-5’-Nucleotidase as a New Target for Cancer Therapy: A Medicinal Chemistry Study
- (2015) Patricia Corbelini et al. CURRENT MEDICINAL CHEMISTRY
- Ecto-Nucleotidase Inhibitors: Recent Developments in Drug Discovery
- (2015) Younis Baqi MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities
- (2014) Gennady G. Yegutkin CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Purinergic Signaling in Liver Disease
- (2014) Byron P. Vaughn et al. DIGESTIVE DISEASES
- Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071
- (2014) Matthias Zebisch et al. JOURNAL OF STRUCTURAL BIOLOGY
- Therapeutic Potentials of Ecto-Nucleoside Triphosphate Diphosphohydrolase, Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase, Ecto-5′-Nucleotidase, and Alkaline Phosphatase Inhibitors
- (2013) Mariya al-Rashida et al. MEDICINAL RESEARCH REVIEWS
- Adenosine receptors as drug targets — what are the challenges?
- (2013) Jiang-Fan Chen et al. NATURE REVIEWS DRUG DISCOVERY
- Role of the ectonucleotidase NTPDase2 in taste bud function
- (2013) Aurelie Vandenbeuch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystallographic Snapshots along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
- (2013) Matthias Zebisch et al. STRUCTURE
- Crystal Structure of a Soluble Form of Human CD73 with Ecto-5′-Nucleotidase Activity
- (2012) Dominic P. H. M. Heuts et al. CHEMBIOCHEM
- Ectonucleotidases in Solid Organ and Allogeneic Hematopoietic Cell Transplantation
- (2012) Petya Chernogorova et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Production of Adenosine by Ectonucleotidases: A Key Factor in Tumor Immunoescape
- (2012) François Ghiringhelli et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Transgenic swine: Expression of human CD39 protects against myocardial injury
- (2012) Debra G. Wheeler et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Superior working memory and behavioural habituation but diminished psychomotor coordination in mice lacking the ecto-5′-nucleotidase (CD73) gene
- (2012) Armin Zlomuzica et al. Purinergic Signalling
- Cellular function and molecular structure of ecto-nucleotidases
- (2012) Herbert Zimmermann et al. Purinergic Signalling
- Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling
- (2012) Karen Knapp et al. STRUCTURE
- Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells
- (2011) Michael Romio et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury
- (2011) Ming Cai et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (NTPDase) 1
- (2011) Matthias Zebisch et al. JOURNAL OF MOLECULAR BIOLOGY
- The GDA1_CD39 superfamily: NTPDases with diverse functions
- (2011) Aileen F. Knowles Purinergic Signalling
- Purinergic signaling in neural development
- (2011) Herbert Zimmermann SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Adenine nucleotide control of coronary blood flow during exercise
- (2010) Mark W. Gorman et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Crystal Structure of a Legionella pneumophila Ecto -Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases
- (2010) Julian P. Vivian et al. STRUCTURE
- Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling
- (2008) M. Zebisch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP and acetylcholine, equal brethren
- (2007) Herbert Zimmermann NEUROCHEMISTRY INTERNATIONAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now