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Title
Cannabidiol: pharmacology and therapeutic targets
Authors
Keywords
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Journal
PSYCHOPHARMACOLOGY
Volume 238, Issue 1, Pages 9-28
Publisher
Springer Science and Business Media LLC
Online
2020-11-22
DOI
10.1007/s00213-020-05712-8
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- The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
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- (2016) A.G. Sartim et al. BEHAVIOURAL BRAIN RESEARCH
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- Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study
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- (2015) Alex F. Manini et al. Journal of Addiction Medicine
- Oral Cannabidiol does not Alter the Subjective, Reinforcing or Cardiovascular Effects of Smoked Cannabis
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- Cannabidiol as a Potential Treatment for Anxiety Disorders
- (2015) Esther M. Blessing et al. Neurotherapeutics
- Molecular Targets of Cannabidiol in Neurological Disorders
- (2015) Clementino Ibeas Bih et al. Neurotherapeutics
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