Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells

Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors

(2020) Ombretta Melaiu et al.   Frontiers in Immunology

Anti-PD-1 and Novel Combinations in the Treatment of Melanoma—An Update

(2020) Frank Friedrich Gellrich et al.   Journal of Clinical Medicine

IL-15 by continuous i.v. infusion to adult patients with solid tumors in a Phase I trial induced dramatic NK cell subset expansion

(2019) Kevin C Conlon et al.   CLINICAL CANCER RESEARCH

Tuning the Tumor Myeloid Microenvironment to Fight Cancer

(2019) Nadine S. Jahchan et al.   Frontiers in Immunology

The Metabolic Signature of Macrophage Responses

(2019) Antonella Viola et al.   Frontiers in Immunology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

(2019) Massimo Locati et al.   Annual Review of Pathology-Mechanisms of Disease

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell–mediated tumor regression

(2019) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New paradigm for stage III melanoma: from surgery to adjuvant treatment

(2019) Paolo Antonio Ascierto et al.   Journal of Translational Medicine

Myeloid Cells in Metastasis

(2019) Agnieszka Swierczak et al.   Cold Spring Harbor Perspectives in Medicine

Developing TRAIL/TRAIL death receptor-based cancer therapies

(2018) Xun Yuan et al.   CANCER AND METASTASIS REVIEWS

Clinical Development of PD-1 in Advanced Melanoma

(2018) Rodrigo Ramella Munhoz et al.   CANCER JOURNAL

Myeloid cell heterogeneity in cancer: not a single cell alike

(2018) Mate Kiss et al.   CELLULAR IMMUNOLOGY

T-bet and Eomes govern differentiation and function of mouse and human NK cells and ILC1

(2018) Jiang Zhang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

(2018) Luiz E. B. Savio et al.   Frontiers in Pharmacology

Diverse Functions of Macrophages in Different Tumor Microenvironments

(2018) Ming Yang et al.   CANCER RESEARCH

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

IL-15 enhanced antibody-dependent cellular cytotoxicity mediated by NK cells and macrophages

(2018) Meili Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquired mechanisms of immune escape in cancer following immunotherapy

(2018) J. Bryan Iorgulescu et al.   Genome Medicine

The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression

(2017) Geoffrey Burnstock et al.   Purinergic Signalling

Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection

(2017) Joaquín Amores-Iniesta et al.   Cell Reports

Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

(2016) Rony Dahan et al.   CANCER CELL

The Multifaceted Role of Perivascular Macrophages in Tumors

(2016) Claire E. Lewis et al.   CANCER CELL

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

HIF1α and metabolic reprogramming in inflammation

(2016) Sarah E. Corcoran et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21

(2016) Kajsa E. Prokopec et al.   JOURNAL OF IMMUNOLOGY

PI3Kγ is a molecular switch that controls immune suppression

(2016) Megan M. Kaneda et al.   NATURE

Targeting natural killer cells in cancer immunotherapy

(2016) Camille Guillerey et al.   NATURE IMMUNOLOGY

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

(2015) R. Hughes et al.   CANCER RESEARCH

Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer

(2015) Kevin C. Conlon et al.   JOURNAL OF CLINICAL ONCOLOGY

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Metabolic Reprograming in Macrophage Polarization

(2014) Silvia Galván-Peña et al.   Frontiers in Immunology

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

(2013) Tyler R. Simpson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proangiogenic TIE2+/CD31+ macrophages are the predominant population of tumor-associated macrophages infiltrating metastatic lymph nodes

(2013) Ok-Hee Kim et al.   MOLECULES AND CELLS

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

ATP release and purinergic signaling in NLRP3 inflammasome activation

(2013) Aurélie Gombault et al.   Frontiers in Immunology

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL