The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review

Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model

(2019) Amanda Cano et al.   JOURNAL OF CONTROLLED RELEASE

Green Tea Catechin Extract Supplementation Does Not Influence Circulating Sex Hormones and Insulin-Like Growth Factor Axis Proteins in a Randomized Controlled Trial of Postmenopausal Women at High Risk of Breast Cancer

(2019) Hamed Samavat et al.   JOURNAL OF NUTRITION

The Role of Insulin Resistance and Protein O-GlcNAcylation in Neurodegeneration

(2019) Suraiya A. Ansari et al.   Frontiers in Neuroscience

Clinical aspects and biomarkers of Alzheimer's disease in Down syndrome

(2018) Panagiotis Zis et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigallocatechin Gallate Reduces Amyloid β-Induced Neurotoxicity via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis

(2018) Ke Du et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Epigallocatechin-3-gallate loaded PEGylated-PLGA nanoparticles: A new anti-seizure strategy for temporal lobe epilepsy

(2018) Amanda Cano et al.   Nanomedicine-Nanotechnology Biology and Medicine

Neuroprotective effects of Baicalein in animal models of Parkinson's disease: A Systematic review of experimental studies

(2018) Qi Zhu et al.   PHYTOMEDICINE

EGCG Nanoparticles Attenuate Aluminum Chloride Induced Neurobehavioral Deficits, Beta Amyloid and Tau Pathology in a Rat Model of Alzheimer’s Disease

(2018) Neha Atulkumar Singh et al.   Frontiers in Aging Neuroscience

Physiological effects of epigallocatechin-3-gallate (EGCG) on energy expenditure for prospective fat oxidation in humans: A systematic review and meta-analysis

(2017) Mahendra P. Kapoor et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease

(2017) Miren Ettcheto et al.   MOLECULAR NEUROBIOLOGY

(−)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer’s disease

(2017) Yufang Guo et al.   NEUROREPORT

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

(2016) Rafael de la Torre et al.   LANCET NEUROLOGY

The activities of amyloids from a structural perspective

(2016) Roland Riek et al.   NATURE

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

(−)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer׳s disease model mice by upregulating neprilysin expression

(2015) Xiang Chang et al.   EXPERIMENTAL CELL RESEARCH

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

(2015) Myles R. Minter et al.   JOURNAL OF NEUROCHEMISTRY

Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies

(2015) Jesus Lovera et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment

(2015) Sylvia Lombardo et al.   NEUROPHARMACOLOGY

Epigallocatechin-3-gallate (EGCG)-Stabilized Selenium Nanoparticles Coated with Tet-1 Peptide To Reduce Amyloid-β Aggregation and Cytotoxicity

(2014) Jingnan Zhang et al.   ACS Applied Materials & Interfaces

Results of a phase II randomized, double-blind, placebo-controlled trial of Polyphenon E in women with persistent high-risk HPV infection and low-grade cervical intraepithelial neoplasia

(2014) Francisco A.R. Garcia et al.   GYNECOLOGIC ONCOLOGY

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

(−)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus

(2013) Ning Jia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

(−)-Epigallocatechin-3-Gallate Ameliorates Learning and Memory Deficits by Adjusting the Balance of TrkA/p75NTR Signaling in APP/PS1 Transgenic Mice

(2013) Mingyan Liu et al.   MOLECULAR NEUROBIOLOGY

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

(2013) Rafael De la Torre et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Changes in Amyloid-  and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein

(2013) L. F. Maia et al.   Science Translational Medicine

Green tea (−)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia

(2012) Regina Biasibetti et al.   BEHAVIOURAL BRAIN RESEARCH

Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells

(2012) Di Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

(2012) Tait D. Shanafelt et al.   CANCER

Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor-Negative Breast Cancer

(2012) K. D. Crew et al.   Cancer Prevention Research

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

(2012) Young-Jung Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Animal models in the drug discovery pipeline for Alzheimer's disease

(2011) Debby Van Dam et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

(2010) Adam Smith et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Green Tea Extract-Induced Lethal Toxicity in Fasted but Not in Nonfasted Dogs

(2010) Kuei-Meng Wu et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE ɛ4 allele

(2010) Wiesje M van der Flier et al.   LANCET NEUROLOGY

Oxidative stress in Alzheimer disease: A possibility for prevention

(2010) David J. Bonda et al.   NEUROPHARMACOLOGY

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro

(2009) J. McLarty et al.   Cancer Prevention Research

Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the Bench

(2009) Malcolm R Macleod et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Green Tea (-)-Epigallocatechin-3-Gallate Inhibits β-Amyloid-Induced Cognitive Dysfunction through Modification of Secretase Activity via Inhibition of ERK and NF-κB Pathways in Mice

(2009) Jae Woong Lee et al.   JOURNAL OF NUTRITION

Exposure and toxicity of green tea polyphenols in fasted and non-fasted dogs

(2009) I.M. Kapetanovic et al.   TOXICOLOGY

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

(2008) Kavon Rezai-Zadeh et al.   BRAIN RESEARCH

(−)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency

(2008) Young Kyoung Lee et al.   BRAIN RESEARCH

Good Laboratory Practice

(2008) Malcolm R. Macleod et al.   STROKE

Effects of green tea extract on learning, memory, behavior and acetylcholinesterase activity in young and old male rats

(2007) Tranum Kaur et al.   BRAIN AND COGNITION

Epigallocatechin gallate (EGCG) suppresses β-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3β activation

(2007) Chih-Li Lin et al.   NEUROBIOLOGY OF AGING