Novel PGC-1α/ATF5 Axis Partly Activates UPRmt and Mediates Cardioprotective Role of Tetrahydrocurcumin in Pathological Cardiac Hypertrophy

Signaling and Regulation of the Mitochondrial Unfolded Protein Response

(2019) Nandhitha Uma Naresh et al.   Cold Spring Harbor Perspectives in Biology

Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload

(2019) Ioannis Smyrnias et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway

(2019) Kaifeng Li et al.   Oxidative Medicine and Cellular Longevity

Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway

(2018) Yintao Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway

(2018) Bin Zhang et al.   Oxidative Medicine and Cellular Longevity

Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt PathwayNovelty and Significance

(2017) Ke-Qiong Deng et al.   HYPERTENSION

Prevalence, Treatment, and Control Rates of Conventional and Ambulatory Hypertension Across 10 Populations in 3 ContinentsNovelty and Significance

(2017) Jesus D. Melgarejo et al.   HYPERTENSION

Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC-1β: In vivo and in vitro studies

(2017) Mengen Zhai et al.   JOURNAL OF PINEAL RESEARCH

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

(2017) Nicolas Diguet et al.   CIRCULATION

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidative Stress and Cardiovascular Dysfunction Associated with Cadmium Exposure: Beneficial Effects of Curcumin and Tetrahydrocurcumin

(2016) Upa Kukongviriyapan et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Improved bioavailability of targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment

(2016) Aramita Ray et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tetrahydrocurcumin in combination with deferiprone attenuates hypertension, vascular dysfunction, baroreflex dysfunction, and oxidative stress in iron-overloaded mice

(2016) Weerapon Sangartit et al.   VASCULAR PHARMACOLOGY

Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload

(2015) G. G. Schiattarella et al.   CIRCULATION

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing thePGC-1α–NRF1/NRF2Pathway and Mitochondrial Respiratory Function in Rats

(2015) Zheng Ping et al.   Oxidative Medicine and Cellular Longevity

Curcumin Differs from Tetrahydrocurcumin for Molecular Targets, Signaling Pathways and Cellular Responses

(2014) Bharat Aggarwal et al.   MOLECULES

Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

(2014) Karina Huynh et al.   PHARMACOLOGY & THERAPEUTICS

Tetrahydrocurcumin Protects against Cadmium-Induced Hypertension, Raised Arterial Stiffness and Vascular Remodeling in Mice

(2014) Weerapon Sangartit et al.   PLoS One

Notch1 cardioprotection in myocardial ischemia/reperfusion involves reduction of oxidative/nitrative stress

(2013) Haifeng Pei et al.   BASIC RESEARCH IN CARDIOLOGY

Induced Overexpression of Na+/Ca2+ Exchanger Does Not Aggravate Myocardial Dysfunction Induced by Transverse Aortic Constriction

(2012) JuFang Wang et al.   JOURNAL OF CARDIAC FAILURE

Oxidative stress and cardiac hypertrophy: a review

(2012) Subir Kumar Maulik et al.   TOXICOLOGY MECHANISMS AND METHODS

Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with l-NAME-induced hypertension

(2011) Saowanee Nakmareong et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Scutellarin exerts its anti-hypertrophic effects via suppressing the Ca2+-mediated calcineurin and CaMKII signaling pathways

(2010) Zhen-Wei Pan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Tetrahydrocurcumin confers protection against amyloid β-induced toxicity

(2010) Shilpa Mishra et al.   NEUROREPORT

Reversal of Cardiac Hypertrophy and Fibrosis From Pressure Overload by Tetrahydrobiopterin

(2008) An L. Moens et al.   CIRCULATION

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE