Structural and functional consequences of reversible lipid asymmetry in living membranes

Lipid Rafts: Controversies Resolved, Mysteries Remain

(2020) Ilya Levental et al.   TRENDS IN CELL BIOLOGY

The role of phosphatidylserine recognition receptors in multiple biological functions

(2020) Mehri Bemani Naeini et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Phosphatidylserine exposure in living cells

(2020) Hye-Won Shin et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Asymmetry across the membrane

(2020) Maria Makarova et al.   Nature Chemical Biology

Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

(2020) Kandice R. Levental et al.   Nature Communications

Interleaflet Coupling of Lipid Nanodomains – Insights From in vitro Systems

(2020) Maria J. Sarmento et al.   Frontiers in Cell and Developmental Biology

Pivotal Role of Interdigitation in Interleaflet Interactions: Implications from Molecular Dynamics Simulations

(2020) Sangjae Seo et al.   Journal of Physical Chemistry Letters

Direct imaging of liquid domains in membranes by cryo-electron tomography

(2020) Caitlin E. Cornell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy

(2020) Frederick A. Heberle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phospholipid distribution in the cytoplasmic membrane of Gram-negative bacteria is highly asymmetric, dynamic, and cell shape-dependent

(2020) Mikhail Bogdanov et al.   Science Advances

How cholesterol stiffens unsaturated lipid membranes

(2020) Saptarshi Chakraborty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Modeling of Realistic Cell Membranes

(2019) Siewert J. Marrink et al.   CHEMICAL REVIEWS

Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase

(2019) Maria E Falzone et al.   eLife

Bilayer membranes with frequent flip-flops have tensionless leaflets

(2019) Markus Sakari Miettinen et al.   NANO LETTERS

Lipid-Assisted Membrane Protein Folding and Topogenesis

(2019) William Dowhan et al.   PROTEIN JOURNAL

The plasma membrane as a mechanochemical transducer

(2019) Anabel-Lise Le Roux et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The role of PS 18:0/18:1 in membrane function

(2019) Tore Skotland et al.   Nature Communications

Flipping the dogma – phosphatidylserine in non-apoptotic cell death

(2019) Inbar Shlomovitz et al.   Cell Communication and Signaling

Long acyl chain ceramides govern cholesterol and cytoskeleton dependence of membrane outer leaflet dynamics

(2019) Anjali Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Apoptosis and eryptosis: Striking differences on biomembrane level

(2018) Kyrylo A. Pyrshev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transverse distribution of plasma membrane bilayer cholesterol: Picking sides

(2018) Theodore L. Steck et al.   TRAFFIC

Nanoscale membrane architecture of healthy and pathological red blood cells

(2018) Andra C. Dumitru et al.   Nanoscale Horizons

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

(2018) Naoki Hisamoto et al.   Nature Communications

C24 Sphingolipids Govern the Transbilayer Asymmetry of Cholesterol and Lateral Organization of Model and Live-Cell Plasma Membranes

(2018) K.C. Courtney et al.   Cell Reports

Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds

(2018) Sonya Entova et al.   eLife

Spatially Resolving the Condensing Effect of Cholesterol in Lipid Bilayers

(2018) Felix Leeb et al.   BIOPHYSICAL JOURNAL

Cell Membranes Resist Flow

(2018) Zheng Shi et al.   CELL

A FRET sensor enables quantitative measurements of membrane charges in live cells

(2017) Yuanqing Ma et al.   NATURE BIOTECHNOLOGY

Structural determinants and functional consequences of protein affinity for membrane rafts

(2017) Joseph H. Lorent et al.   Nature Communications

Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner

(2016) Tomasz Róg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

On the molecular mechanism of flippase- and scramblase-mediated phospholipid transport

(2016) Cédric Montigny et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Polyunsaturated Lipids Regulate Membrane Domain Stability by Tuning Membrane Order

(2016) Kandice R. Levental et al.   BIOPHYSICAL JOURNAL

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol

(2016) Shu-Lin Liu et al.   Nature Chemical Biology

Nonadditive Compositional Curvature Energetics of Lipid Bilayers

(2016) A. J. Sodt et al.   PHYSICAL REVIEW LETTERS

Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane

(2016) Edouard M. Bevers et al.   PHYSIOLOGICAL REVIEWS

Phosphatidylserine exposure is required for ADAM17 sheddase function

(2016) Anselm Sommer et al.   Nature Communications

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

(2015) Brent Neumann et al.   NATURE

Roles and regulation of phospholipid scramblases

(2014) Karthik M. Kodigepalli et al.   FEBS LETTERS

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Membrane raft association is a determinant of plasma membrane localization

(2014) B. B. Diaz-Rohrer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ionic protein–lipid interaction at the plasma membrane: what can the charge do?

(2014) Lunyi Li et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phospholipid Scramblase-1-Induced Lipid Reorganization Regulates Compensatory Endocytosis in Neuroendocrine Cells

(2013) S. Ory et al.   JOURNAL OF NEUROSCIENCE

Monolayer spontaneous curvature of raft-forming membrane lipids

(2013) Benjamin Kollmitzer et al.   Soft Matter

Concluding remarks Back to the future: mechanics and thermodynamics of lipid biomembranes

(2012) E. Evans et al.   FARADAY DISCUSSIONS

A Role for Sphingomyelin-Rich Lipid Domains in the Accumulation of Phosphatidylinositol-4,5-Bisphosphate to the Cleavage Furrow during Cytokinesis

(2012) M. Abe et al.   MOLECULAR AND CELLULAR BIOLOGY

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina

(2012) L. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphatidylserine directly and positively regulates fusion of myoblasts into myotubes

(2011) Jaemin Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY

Flip-Flop-Induced Relaxation of Bending Energy: Implications for Membrane Remodeling

(2009) R.J. Bruckner et al.   BIOPHYSICAL JOURNAL

PI(4,5)P2 Degradation Promotes the Formation of Cytoskeleton-Free Model Membrane Systems

(2009) Heiko Keller et al.   CHEMPHYSCHEM

Molecular View of Cholesterol Flip-Flop and Chemical Potential in Different Membrane Environments

(2009) W. F. Drew Bennett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyunsaturated fatty acid–cholesterol interactions: Domain formation in membranes

(2008) Stephen R. Wassall et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible

(2008) R. J. Goodyear et al.   JOURNAL OF NEUROSCIENCE

Galectin-1 Induces Reversible Phosphatidylserine Exposure at the Plasma Membrane

(2008) Sean R. Stowell et al.   MOLECULAR BIOLOGY OF THE CELL