Research Progress of the Biosynthesis of Natural Bio-Antibacterial Agent Pulcherriminic Acid in Bacillus

Multistep metabolic engineering of Bacillus licheniformis to improve pulcherriminic acid production

(2020) Shiyi Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic Engineering of Main Transcription Factors in Carbon, Nitrogen, and Phosphorus Metabolisms for Enhanced Production of Bacitracin in Bacillus licheniformis

(2019) Dongbo Cai et al.   ACS Synthetic Biology

Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm

(2019) Sofia Arnaouteli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased flux through the TCA cycle enhances bacitracin production by Bacillus licheniformis DW2

(2018) Zhaoyuan Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Global analysis of prokaryotic tRNA-derived cyclodipeptide biosynthesis

(2018) Michael A. Skinnider et al.   BMC GENOMICS

Aminoacyl-tRNA synthetases: Structure, function, and drug discovery

(2018) Vijayakumar Rajendran et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Structural basis for partition of the cyclodipeptide synthases into two subfamilies

(2018) Gabrielle Bourgeois et al.   JOURNAL OF STRUCTURAL BIOLOGY

Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism

(2018) Anja Greule et al.   NATURAL PRODUCT REPORTS

Cyclization Reaction Catalyzed by Cyclodipeptide Synthases Relies on a Conserved Tyrosine Residue

(2018) Emmanuelle Schmitt et al.   Scientific Reports

Regulation of the Synthesis and Secretion of the Iron Chelator Cyclodipeptide Pulcherriminic Acid in Bacillus licheniformis

(2018) Dong Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Functional and evolutionary characterization of a secondary metabolite gene cluster in budding yeasts

(2018) David J. Krause et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

(2018) Tingting Yao et al.   Nature Communications

Mutations of Residues in Pocket P1 of a Cyclodipeptide Synthase Strongly Increase Product Formation

(2017) Kirsten Brockmeyer et al.   JOURNAL OF NATURAL PRODUCTS

Cyclodipeptides: An Overview of Their Biosynthesis and Biological Activity

(2017) Awdhesh Mishra et al.   MOLECULES

Untangling the transcription regulatory network of the bacitracin synthase operon in Bacillus licheniformis DW2

(2017) Dong Wang et al.   RESEARCH IN MICROBIOLOGY

Overcoming substrate limitations for improved production of ethylene in E. coli

(2016) Sean Lynch et al.   Biotechnology for Biofuels

The MarR-like protein PchR (YvmB) regulates expression of genes involved in pulcherriminic acid biosynthesis and in the initiation of sporulation in Bacillus subtilis

(2016) Paola Randazzo et al.   BMC MICROBIOLOGY

Engineering Escherichia coli to produce branched-chain fatty acids in high percentages

(2016) Gayle J. Bentley et al.   METABOLIC ENGINEERING

Formation of self-organized periodic patterns around yeasts secreting a precursor of a red pigment

(2016) Vytautas Melvydas et al.   MICROBIOLOGICAL RESEARCH

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity

(2015) Isabelle B Jacques et al.   Nature Chemical Biology

Rational and combinatorial tailoring of bioactive cyclic dipeptides

(2015) Tobias W. Giessen et al.   Frontiers in Microbiology

The tRNA-Dependent Biosynthesis of Modified Cyclic Dipeptides

(2014) Tobias Giessen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

(2014) Mireille Moutiez et al.   Nature Communications

Engineering of transcriptional regulators enhances microbial stress tolerance

(2013) Zhanglin Lin et al.   BIOTECHNOLOGY ADVANCES

Pushing product formation to its limit: Metabolic engineering of Corynebacterium glutamicum for l-leucine overproduction

(2013) Michael Vogt et al.   METABOLIC ENGINEERING

Origins of P450 diversity

(2013) H. Sezutsu et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cyclic dipeptides exhibit potency for scavenging radicals

(2012) Tadashi Furukawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Linear and cyclic dipeptides with antimalarial activity

(2012) Lemuel Pérez-Picaso et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

(2012) Alan D. Borthwick   CHEMICAL REVIEWS

Antimicrobial and Biofilm Inhibiting Diketopiperazines

(2012) M. P. de Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

(2012) Pascal Belin et al.   NATURAL PRODUCT REPORTS

2,5-Diketopiperazines as Neuroprotective Agents

(2011) C. Cornacchia et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

(2011) Ludovic Sauguet et al.   NUCLEIC ACIDS RESEARCH

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

(2011) L. Bonnefond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Biochemical Characterization of the Cytochrome P450 CypX (CYP134A1) fromBacillus subtilis: A Cyclo-l-leucyl-l-leucyl Dipeptide Oxidase

(2010) Max J. Cryle et al.   BIOCHEMISTRY

Progress in tracing the evolutionary paths of cytochrome P450

(2010) David R. Nelson   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Discovery of a Class of Diketopiperazines as Antiprion Compounds

(2010) Maria Laura Bolognesi et al.   ChemMedChem

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

(2010) Matthew W Vetting et al.   Nature Chemical Biology

Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber

(2010) X.-X. Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

(2010) J. Rittle et al.   SCIENCE

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes

(2009) Muriel Gondry et al.   Nature Chemical Biology