The tRNA-Dependent Biosynthesis of Modified Cyclic Dipeptides

Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei

(2014) M. Moutiez et al.   NUCLEIC ACIDS RESEARCH

A tRNA-Dependent Two-Enzyme Pathway for the Generation of Singly and Doubly Methylated Ditryptophan 2,5-Diketopiperazines

(2013) Tobias W. Giessen et al.   BIOCHEMISTRY

Insights into the Generation of Structural Diversity in a tRNA-Dependent Pathway for Highly Modified Bioactive Cyclic Dipeptides

(2013) Tobias W. Giessen et al.   CHEMISTRY & BIOLOGY

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

(2012) Alan D. Borthwick   CHEMICAL REVIEWS

Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity

(2012) Tobias W. Giessen et al.   FEBS LETTERS

New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039

(2012) Qingbo Zhang et al.   JOURNAL OF ANTIBIOTICS

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

(2012) Pascal Belin et al.   NATURAL PRODUCT REPORTS

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

(2012) Sarah M Barry et al.   Nature Chemical Biology

Nonribosomal Peptide Synthesis in Animals: The Cyclodipeptide Synthase of Nematostella

(2011) Jérôme Seguin et al.   CHEMISTRY & BIOLOGY

A Single Cluster of Coregulated Genes Encodes the Biosynthesis of the Mycotoxins Roquefortine C and Meleagrin in Penicillium chrysogenum

(2011) Carlos García-Estrada et al.   CHEMISTRY & BIOLOGY

Biochemical Characterization of Indole Prenyltransferases

(2011) Xia Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Pyrones and Diketopiperazine Derivatives from the Marine-Derived Actinomycete Nocardiopsis dassonvillei HR10-5

(2011) Peng Fu et al.   JOURNAL OF NATURAL PRODUCTS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

The tRNA synthetase paralog PoxA modifies elongation factor-P with (R)-β-lysine

(2011) Hervé Roy et al.   Nature Chemical Biology

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

(2011) Ludovic Sauguet et al.   NUCLEIC ACIDS RESEARCH

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

(2011) L. Bonnefond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci

(2011) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transkingdom signaling based on bacterial cyclodipeptides with auxin activity in plants

(2011) R. Ortiz-Castro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding the Logic of the tRNA Regiospecificity of Nonribosomal FemXWv Aminoacyl Transferase

(2010) Matthieu Fonvielle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Structural and Biochemical Characterization of the Cytochrome P450 CypX (CYP134A1) fromBacillus subtilis: A Cyclo-l-leucyl-l-leucyl Dipeptide Oxidase

(2010) Max J. Cryle et al.   BIOCHEMISTRY

Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis

(2010) L Aravind et al.   Biology Direct

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Biochemical Characterization of a Novel Indole Prenyltransferase from Streptomyces sp. SN-593

(2010) S. Takahashi et al.   JOURNAL OF BACTERIOLOGY

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

(2010) Matthew W Vetting et al.   Nature Chemical Biology

A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P

(2010) Tatsuo Yanagisawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design

(2010) Minyun Zhou et al.   NUCLEIC ACIDS RESEARCH

A new bioinformatics analysis tools framework at EMBL-EBI

(2010) M. Goujon et al.   NUCLEIC ACIDS RESEARCH

Preparation of pyrrolo[2,3-b]indoles carrying a β-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT

(2010) Wen-Bing Yin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Simultaneous C7- and N1-prenylation of cyclo-l-Trp-l-Trp catalyzed by a prenyltransferase from Aspergillus oryzae

(2010) Hui-Xi Zou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Applications of dimethylallyltryptophan synthases and other indole prenyltransferases for structural modification of natural products

(2009) Shu-Ming Li   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

tRNA as an active chemical scaffold for diverse chemical transformations

(2009) Christopher S. Francklyn et al.   FEBS LETTERS

Broad Range Amino Acid Specificity of RNA-dependent Lipid Remodeling by Multiple Peptide Resistance Factors

(2009) Hervé Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes

(2009) Muriel Gondry et al.   Nature Chemical Biology

Evolution of aromatic prenyltransferases in the biosynthesis of indole derivatives

(2009) Shu-Ming Li   PHYTOCHEMISTRY

The thaxtomin phytotoxins: Sources, synthesis, biosynthesis, biotransformation and biological activity

(2009) Russell R. King et al.   PHYTOCHEMISTRY

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

(2009) P. Belin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtmPT2, anN-Prenyltransferase fromAspergillus fumigatus, Catalyses the Last Step in the Biosynthesis of Fumitremorgin B

(2008) Alexander Grundmann et al.   CHEMBIOCHEM

Acetylaszonalenin Biosynthesis inNeosartorya fischeri

(2008) Wen-Bing Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis and Structures of Cyclomarins and Cyclomarazines, Prenylated Cyclic Peptides of Marine Actinobacterial Origin

(2008) Andrew W. Schultz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA-dependent lipid remodeling by bacterial multiple peptide resistance factors

(2008) H. Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The evolution of gene collectives: How natural selection drives chemical innovation

(2008) M. A. Fischbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA