Pterostilbene Alleviates Aβ 1‐42 ‐Induced Cognitive Dysfunction via Inhibition of Oxidative Stress by Activating Nrf2 Signaling Pathway

Multi-year Quantitative Evaluation of Stilbenoids Levels Among Selected Muscadine Grape Cultivars

(2019) Devaiah Kambiranda et al.   MOLECULES

Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice

(2019) Paula S. Frost et al.   Cell Death & Disease

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

(2019) Gahee Bahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress

(2019) Yiru Wang et al.   Aging-US

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Progressive Circuit Changes during Learning and Disease

(2019) Alison L. Barth et al.   NEURON

Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation

(2019) Haixiao Liu et al.   Frontiers in Immunology

Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease

(2018) D. Allan Butterfield et al.   JOURNAL OF ALZHEIMERS DISEASE

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer’s Amyloid-β Oligomers

(2018) Mikhail A. Kostylev et al.   MOLECULAR CELL

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1–42 toxicity in astrocytes

(2017) Nishani T Hettiarachchi et al.   Cell Death & Disease

NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

(2017) Ana I. Rojo et al.   Redox Biology

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

(2016) Anju Singh et al.   ACS Chemical Biology

Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism

(2016) María Benlloch et al.   ANTIOXIDANTS & REDOX SIGNALING

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease

(2016) Tianfang Jiang et al.   PROGRESS IN NEUROBIOLOGY

High glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells

(2016) Hyun Jik Lee et al.   Scientific Reports

Assessing rodent hippocampal involvement in the novel object recognition task. A review

(2015) Sarah J. Cohen et al.   BEHAVIOURAL BRAIN RESEARCH

p62 links autophagy and Nrf2 signaling

(2015) Tao Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

(2015) Lauren E. Tebay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structural basis of Keap1 interactions with Nrf2

(2015) Peter Canning et al.   FREE RADICAL BIOLOGY AND MEDICINE

HO-1 Signaling Activation by Pterostilbene Treatment Attenuates Mitochondrial Oxidative Damage Induced by Cerebral Ischemia Reperfusion Injury

(2015) Yang Yang et al.   MOLECULAR NEUROBIOLOGY

Effects of pterostilbene and resveratrol on brain and behavior

(2015) Shibu M. Poulose et al.   NEUROCHEMISTRY INTERNATIONAL

Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2

(2014) Elango Bhakkiyalakshmi et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production

(2014) N Hettiarachchi et al.   Cell Death & Disease

Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers

(2013) C. P. Figueiredo et al.   JOURNAL OF NEUROSCIENCE

Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter

(2013) Atsushi Maruyama et al.   NUCLEIC ACIDS RESEARCH

Antioxidant gene therapy against neuronal cell death

(2013) Juliana Navarro-Yepes et al.   PHARMACOLOGY & THERAPEUTICS

Interleukin-13/-4-Induced Oxidative Stress Contributes to Death of Hippocampal Neurons in Aβ1-42-Treated Hippocampus In Vivo

(2012) J.H. Nam et al.   ANTIOXIDANTS & REDOX SIGNALING

Pterostilbene Is More Potent than Resveratrol in Preventing Azoxymethane (AOM)-Induced Colon Tumorigenesis via Activation of the NF-E2-Related Factor 2 (Nrf2)-Mediated Antioxidant Signaling Pathway

(2011) Yi-Siou Chiou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hippocampal Extracellular Signal-Regulated Kinase Signaling has a Role in Passive Avoidance Memory Retrieval Induced by GABAA Receptor Modulation in Mice

(2011) Dong Hyun Kim et al.   NEUROPSYCHOPHARMACOLOGY

Cognitive and Emotional Alterations Are Related to Hippocampal Inflammation in a Mouse Model of Metabolic Syndrome

(2011) Anne-Laure Dinel et al.   PLoS One

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?

(2009) Federico Sesti et al.   TRENDS IN CELL BIOLOGY