Structural Basis for Virulence Activation of Francisella tularensis

Structural basis for transcription inhibition by E. coli SspA

(2020) Fulin Wang et al.   NUCLEIC ACIDS RESEARCH

Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase

(2019) Alexis Jaramillo Cartagena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure ofEscherichia coliσ70RNA polymerase and promoter DNA complex revealed a role of σ non-conserved region during the open complex formation

(2018) Anoop Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Newly emerging ulceroglandular tularaemia in Western Austria

(2018) Andrea Schroll et al.   Ticks and Tick-Borne Diseases

Novel (p)ppGpp Binding and Metabolizing Proteins of Escherichia coli

(2018) Yong Zhang et al.   mBio

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Tularemia in Germany—A Re-emerging Zoonosis

(2018) Mirko Faber et al.   Frontiers in Cellular and Infection Microbiology

Affinity-based capture and identification of protein effectors of the growth regulator ppGpp

(2018) Boyuan Wang et al.   Nature Chemical Biology

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Dissection of the molecular circuitry controlling virulence in Francisella tularensis

(2017) Bonnie J. Cuthbert et al.   GENES & DEVELOPMENT

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex

(2017) Jin Young Kang et al.   eLife

Secreted Effectors Encoded within and outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth

(2016) Aria Eshraghi et al.   Cell Host & Microbe

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

ppGpp Binding to a Site at the RNAP-DksA Interface Accounts for Its Dramatic Effects on Transcription Initiation during the Stringent Response

(2016) Wilma Ross et al.   MOLECULAR CELL

Local and global regulation of transcription initiation in bacteria

(2016) Douglas F. Browning et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis of transcription activation

(2016) Y. Feng et al.   SCIENCE

Diversity in (p)ppGpp metabolism and effectors

(2015) Kuanqing Liu et al.   CURRENT OPINION IN MICROBIOLOGY

Ubiquitous Promoter-Localization of Essential Virulence Regulators in Francisella tularensis

(2015) Kathryn M. Ramsey et al.   PLoS Pathogens

Structure of a bacterial RNA polymerase holoenzyme open promoter complex

(2015) Brian Bae et al.   eLife

Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA)

(2015) Bonnie J. Cuthbert et al.   PLoS One

Bacterial Sigma Factors: A Historical, Structural, and Genomic Perspective

(2014) Andrey Feklístov et al.   Annual Review of Microbiology

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism

(2014) Alistair B. Russell et al.   Cell Host & Microbe

Francisella tularensisas a potential agent of bioterrorism?

(2014) Max Maurin   Expert Review of Anti-Infective Therapy

Coordinate Control of Virulence Gene Expression in Francisella tularensis Involves Direct Interaction between Key Regulators

(2014) A. E. Rohlfing et al.   JOURNAL OF BACTERIOLOGY

Evolution toward high-level fluoroquinolone resistance in Francisella species

(2013) Vivien Sutera et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Magic Spot: A ppGpp Binding Site on E. coli RNA Polymerase Responsible for Regulation of Transcription Initiation

(2013) Wilma Ross et al.   MOLECULAR CELL

The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex

(2013) Yuhong Zuo et al.   MOLECULAR CELL

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

Direct binding targets of the stringent response alarmone (p)ppGpp

(2012) Usheer Kanjee et al.   MOLECULAR MICROBIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Francisella RNA polymerase contains a heterodimer of non-identical α subunits

(2011) Damir Mukhamedyarov et al.   BMC MOLECULAR BIOLOGY

Mechanism of Bacterial Transcription Initiation: RNA Polymerase - Promoter Binding, Isomerization to Initiation-Competent Open Complexes, and Initiation of RNA Synthesis

(2011) Ruth M. Saecker et al.   JOURNAL OF MOLECULAR BIOLOGY

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Phenotypic and genetic characterization of macrolide resistance in Francisella tularensis subsp. holarctica biovar I

(2010) Brieuc Gestin et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification of ciprofloxacin resistance by SimpleProbe™, High Resolution Melt and Pyrosequencing™ nucleic acid analysis in biothreat agents: Bacillus anthracis, Yersinia pestis and Francisella tularensis

(2010) Bonnie M. Loveless et al.   MOLECULAR AND CELLULAR PROBES

The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling

(2010) Jeanette E. Bröms et al.   Frontiers in Microbiology

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

(2009) Jeffrey R. Barker et al.   MOLECULAR MICROBIOLOGY

Small Molecule Control of Virulence Gene Expression in Francisella tularensis

(2009) James C. Charity et al.   PLoS Pathogens

Identification of fevR, a Novel Regulator of Virulence Gene Expression in Francisella novicida

(2008) A. Brotcke et al.   INFECTION AND IMMUNITY

Analysis of RNA polymerase-promoter complex formation

(2008) Wilma Ross et al.   METHODS