Cannabidiol prevents priming- and stress-induced reinstatement of the conditioned place preference induced by cocaine in mice

Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice

(2020) M.P. García-Pardo et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Sex Differences and the Role of Estradiol in Mesolimbic Reward Circuits and Vulnerability to Cocaine and Opiate Addiction

(2020) Saurabh S. Kokane et al.   Frontiers in Behavioral Neuroscience

Cannabinoid Ligands Targeting TRP Channels

(2019) Chanté Muller et al.   Frontiers in Molecular Neuroscience

Cannabidiol as a Novel Candidate Alcohol Use Disorder Pharmacotherapy: A Systematic Review

(2019) Jasmine Turna et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Cannabidiol modulates the expression of neuroinflammatory factors in stress- and drug-induced reinstatement of methamphetamine in extinguished rats

(2019) Saeideh Karimi-Haghighi et al.   ADDICTION BIOLOGY

Gender differences in the effects of cannabidiol on ethanol binge drinking in mice

(2019) Adrián Viudez-Martínez et al.   ADDICTION BIOLOGY

The pharmacological reduction of hippocampal neurogenesis attenuates the protective effects of cannabidiol on cocaine voluntary intake

(2019) Miguel Ángel Luján et al.   ADDICTION BIOLOGY

Dopamine D4 receptor gene expression plays important role in extinction and reinstatement of cocaine-seeking behavior in mice

(2019) Mala Ananth et al.   BEHAVIOURAL BRAIN RESEARCH

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms

(2019) Claudia Calpe-López et al.   MOLECULES

Transient receptor potential vanilloid 1 mediates cocaine reinstatement via the D1 dopamine receptor in the nucleus accumbens

(2019) In-Jee You et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-TH1A and TRPV1 receptor mechanisms

(2019) Ewa Galaj et al.   NEUROPHARMACOLOGY

Cannabidiol attenuates aggressive behavior induced by social isolation in mice: Involvement of 5-HT1A and CB1 receptors

(2019) Alice Hartmann et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The treatment of cocaine use disorder

(2019) Kyle M. Kampman   Science Advances

Cannabidiol does not display drug abuse potential in mice behavior

(2018) Adrián Viudez-Martínez et al.   ACTA PHARMACOLOGICA SINICA

The Pharmacokinetics and the Pharmacodynamics of Cannabinoids

(2018) C.J. Lucas et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal

(2018) Francisco Navarrete et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of cannabidiol plus naltrexone on motivation and ethanol consumption

(2018) Adrián Viudez-Martínez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors

(2018) Mylyne Tham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol Inhibits Endocannabinoid Signaling in Autaptic Hippocampal Neurons

(2018) Alex Straiker et al.   MOLECULAR PHARMACOLOGY

Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle

(2018) Gustavo Gonzalez-Cuevas et al.   NEUROPSYCHOPHARMACOLOGY

Cannabidiol inhibits priming-induced reinstatement of methamphetamine in REM sleep deprived rats

(2018) Saeideh Karimi-Haghighi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats

(2018) Gracie L Hay et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Repeated Cannabidiol treatment reduces cocaine intake and modulates neural proliferation and CB1R expression in the mouse hippocampus

(2018) Miguel Ángel Luján et al.   NEUROPHARMACOLOGY

Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age

(2018) José A. Crippa et al.   Frontiers in Immunology

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

(2018) Lesley Taylor et al.   CNS DRUGS

Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

(2018) Ila M. Linares et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Cannabidiol: State of the art and new challenges for therapeutic applications

(2017) Simona Pisanti et al.   PHARMACOLOGY & THERAPEUTICS

Cannabidiol: Swinging the Marijuana Pendulum From ‘Weed’ to Medication to Treat the Opioid Epidemic

(2017) Yasmin L. Hurd   TRENDS IN NEUROSCIENCES

Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

(2017) Antonio W. Zuardi et al.   Frontiers in Pharmacology

Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats

(2016) Cristiane Ribeiro de Carvalho et al.   ADDICTION BIOLOGY

Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation?

(2016) Natalie E. Zlebnik et al.   Annual Review of Neuroscience

Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine

(2016) Cody A. Siciliano et al.   JOURNAL OF NEUROSCIENCE

Effects of an acute cannabidiol treatment on cocaine self-administration and cue-induced cocaine seeking in male rats

(2016) Ashraf Mahmud et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness

(2016) M. C. Arenas et al.   PSYCHOPHARMACOLOGY

Cannabidiol is a partial agonist at dopamine D2High receptors, predicting its antipsychotic clinical dose

(2016) P Seeman   Translational Psychiatry

Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

(2015) R B Laprairie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

(2015) John R Mantsch et al.   NEUROPSYCHOPHARMACOLOGY

Cannabidiol as a Potential Treatment for Anxiety Disorders

(2015) Esther M. Blessing et al.   Neurotherapeutics

Molecular Targets of Cannabidiol in Neurological Disorders

(2015) Clementino Ibeas Bih et al.   Neurotherapeutics

Classic Studies on the Interaction of Cocaine and the Dopamine Transporter

(2015) Vivek Verma   Clinical Psychopharmacology and Neuroscience

Effects of cannabidiol on the function of α7-nicotinic acetylcholine receptors

(2013) Mohamed Mahgoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Rhodiola roseaImpairs Acquisition and Expression of Conditioned Place Preference Induced by Cocaine

(2013) Federica Titomanlio et al.   Evidence-based Complementary and Alternative Medicine

Influence of Sex Differences and Gonadal Hormones on Cocaine Addiction

(2013) V. Quinones-Jenab et al.   ILAR JOURNAL

Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1Areceptors in the dorsal raphe nucleus

(2012) Vicky Katsidoni et al.   ADDICTION BIOLOGY

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

(2012) F M Leweke et al.   Translational Psychiatry

Synaptic Adaptations in the Nucleus Accumbens Caused by Experiences Linked to Relapse

(2011) Patrick E. Rothwell et al.   BIOLOGICAL PSYCHIATRY

Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum

(2011) Pablo Pandolfo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour

(2011) Serena Deiana et al.   PSYCHOPHARMACOLOGY

The Nonpsychotropic Cannabinoid Cannabidiol Modulates and Directly Activates Alpha-1 and Alpha-1-Beta Glycine Receptor Function

(2009) Jörg Ahrens et al.   PHARMACOLOGY

Social experiences affect reinstatement of cocaine-induced place preference in mice

(2009) Bruno Ribeiro Do Couto et al.   PSYCHOPHARMACOLOGY

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A neuropeptide-centric view of psychostimulant addiction

(2008) B Boutrel   BRITISH JOURNAL OF PHARMACOLOGY

The binding sites for cocaine and dopamine in the dopamine transporter overlap

(2008) Thijs Beuming et al.   NATURE NEUROSCIENCE

Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats

(2008) Amine Bahi et al.   PSYCHOPHARMACOLOGY

Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

(2008) Alline Cristina Campos et al.   PSYCHOPHARMACOLOGY

Increase in matrix metalloproteinase-9 levels in the rat medial prefrontal cortex after cocaine reinstatement of conditioned place preference

(2008) Travis E. Brown et al.   SYNAPSE

Cannabidiol potentiates pharmacological effects of Δ9-tetrahydrocannabinol via CB1 receptor-dependent mechanism

(2007) Kazuhide Hayakawa et al.   BRAIN RESEARCH

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY