Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model

Nicotinamide Adenine Dinucleotide Phosphate Oxidase and Neurodegenerative Diseases: Mechanisms and Therapy

(2020) Liyan Hou et al.   ANTIOXIDANTS & REDOX SIGNALING

Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration

(2020) Qingshan Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration

(2020) Zhan Zhao et al.   Journal of Neuroinflammation

Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke

(2020) Ladonya Jackson et al.   Journal of Neuroinflammation

A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

(2020) He-Yang Zhang et al.   Journal of Neuroinflammation

Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress

(2020) Liyan Hou et al.   TOXICOLOGY LETTERS

Astrocyte function from information processing to cognition and cognitive impairment

(2019) Mirko Santello et al.   NATURE NEUROSCIENCE

Minocycline Relieves Depressive-Like Behaviors in Rats With Bone Cancer Pain by Inhibiting Microglia Activation in Hippocampus

(2019) Jiajia Dai et al.   ANESTHESIA AND ANALGESIA

Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice

(2019) Ya-Jing Liang et al.   BRAIN BEHAVIOR AND IMMUNITY

NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis

(2019) Liyan Hou et al.   TOXICOLOGY

Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model

(2019) Liyan Hou et al.   Redox Biology

Chronic inflammation, cognitive impairment, and distal brain region alteration following intracerebral hemorrhage

(2019) Elaine Shi et al.   FASEB JOURNAL

Methyl jasmonate abrogates rotenone-induced parkinsonian-like symptoms through inhibition of oxidative stress, release of pro-inflammatory cytokines, and down-regulation of immnopositive cells of NF-κB and α-synuclein expressions in mice

(2019) Akinyinka O. Alabi et al.   NEUROTOXICOLOGY

Atorvastatin Relieves Cognitive Disorder After Sepsis Through Reverting Inflammatory Cytokines, Oxidative Stress, and Neuronal Apoptosis in Hippocampus

(2019) Jianmei Tian et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Enhancement of ATP production ameliorates motor and cognitive impairments in a mouse model of MPTP−induced Parkinson's disease

(2019) Hidaka Haga et al.   NEUROCHEMISTRY INTERNATIONAL

Lesion of the Locus Coeruleus Damages Learning and Memory Performance in Paraquat and Maneb-induced Mouse Parkinson’s Disease Model

(2019) Liyan Hou et al.   NEUROSCIENCE

Maresin 1 Improves Cognitive Decline and Ameliorates Inflammation in a Mouse Model of Alzheimer’s Disease

(2019) Ping Yin et al.   Frontiers in Cellular Neuroscience

1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis

(2019) Rong-hao Mu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Adenosine A 2A receptor involves in neuroinflammation-mediated cognitive decline through activating microglia under acute hypobaric hypoxia

(2018) Peng-Zhi Chen et al.   BEHAVIOURAL BRAIN RESEARCH

Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease

(2018) Lorraine Hamelin et al.   BRAIN

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP

(2018) Xiaoxia Yang et al.   FASEB JOURNAL

Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice

(2018) Xianwen Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antimanic activity of minocycline in a GBR12909-induced model of mania in mice: Possible role of antioxidant and neurotrophic mechanisms

(2018) Ana Isabelle G. de Queiroz et al.   JOURNAL OF AFFECTIVE DISORDERS

Risk factors for non-motor symptoms in Parkinson's disease

(2018) Johan Marinus et al.   LANCET NEUROLOGY

The effect of chronic stimulation of serotonin receptor type 7 on recognition, passive avoidance memory, hippocampal long-term potentiation, and neuronal apoptosis in the amyloid β protein treated rat

(2018) Siamak Shahidi et al.   PSYCHOPHARMACOLOGY

Hypertension and Diagnosis of Parkinson’s Disease: A Meta-Analysis of Cohort Studies

(2018) Liyan Hou et al.   Frontiers in Neurology

Microglia play an active role in obesity-associated cognitive decline

(2018) Elise C. Cope et al.   JOURNAL OF NEUROSCIENCE

Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration

(2018) Sheng Song et al.   MOLECULAR NEUROBIOLOGY

Microglial Implication in Parkinson’s Disease: Loss of Beneficial Physiological Roles or Gain of Inflammatory Functions?

(2018) Cynthia Lecours et al.   Frontiers in Cellular Neuroscience

Pupillary Response to Negative Emotional Stimuli Is Differentially Affected in Meditation Practitioners

(2017) Alejandra Vasquez-Rosati et al.   Frontiers in Human Neuroscience

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity

(2017) Eva Czirr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Cognitive impairment in Parkinson's disease: impact on quality of life of carers

(2016) RA Lawson et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer’s Disease and Parkinson’s Disease Dementia?

(2016) Grazia D. Femminella et al.   JOURNAL OF ALZHEIMERS DISEASE

Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits

(2016) Xi Feng et al.   Journal of Neuroinflammation

Non-motor symptoms in Parkinson's disease

(2016) Ronald F. Pfeiffer   PARKINSONISM & RELATED DISORDERS

Neuroprotective effect of curcumin as evinced by abrogation of rotenone-induced motor deficits, oxidative and mitochondrial dysfunctions in mouse model of Parkinson's disease

(2016) Dharmendra K. Khatri et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria

(2016) Vibeke Bruinenberg et al.   Nutrients

Bone marrow mesenchymal stem cells attenuate 2,5-hexanedione-induced neuronal apoptosis through a NGF/AKT-dependent pathway

(2016) Qingshan Wang et al.   Scientific Reports

Parkinson’s disease dementia: a neural networks perspective

(2015) James Gratwicke et al.   BRAIN

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models

(2015) Qingshan Wang et al.   BRAIN

Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: Evidence, pathophysiology and treatment implications

(2015) Joshua D. Rosenblat et al.   JOURNAL OF AFFECTIVE DISORDERS

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Mild cognitive impairment is linked with faster rate of cortical thinning in patients with Parkinson’s disease longitudinally

(2014) Alexandru Hanganu et al.   BRAIN

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease

(2014) Hélène Hall et al.   BRAIN

Minocycline modulates neuropathic pain behaviour and cortical M1–M2 microglial gene expression in a rat model of depression

(2014) Nikita N. Burke et al.   BRAIN BEHAVIOR AND IMMUNITY

Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase

(2014) Q. Wang et al.   JOURNAL OF NEUROSCIENCE

Oral Supplements of Aqueous Extract of Tomato Seeds Alleviate Motor Abnormality, Oxidative Impairments and Neurotoxicity Induced by Rotenone in Mice: Relevance to Parkinson’s Disease

(2014) Krishna Gokul et al.   NEUROCHEMICAL RESEARCH

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life

(2014) Rachael A. Lawson et al.   PARKINSONISM & RELATED DISORDERS

Unexpected Improvements of Spatial Learning and Memory Abilities in Chronic Rotenone Intoxicated Mice

(2014) Fengju Jia et al.   PLoS One

Bcl-xL in neuroprotection and plasticity

(2014) Elizabeth A. Jonas et al.   Frontiers in Physiology

Lack of long-term changes in circadian, locomotor, and cognitive functions in acute and chronic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse models of parkinson’s disease

(2013) Karim Fifel et al.   CHRONOBIOLOGY INTERNATIONAL

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Neuropsychological profile in patients with early stage of Parkinson's disease in Taiwan

(2012) Rwei-Ling Yu et al.   PARKINSONISM & RELATED DISORDERS

Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain

(2010) Julia W. Cohen et al.   SYNAPSE

Minocycline and neurodegenerative diseases

(2008) Hye-Sun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Dementia in Parkinsonʼs disease

(2008) Dag Aarsland et al.   CURRENT OPINION IN NEUROLOGY