Human Immunodeficiency Virus–Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction

Do Combination Antiretroviral Therapy (cART) Regimens for HIV Infection Feature Diverse T-cell Phenotypes and Inflammatory Profiles?

(2020) Camilla Tincati et al.   Open Forum Infectious Diseases

HIV and the Gut Microbiota: Composition, Consequences, and Avenues for Amelioration

(2019) Ivan Vujkovic-Cvijin et al.   Current HIV/AIDS Reports

Plasma Levels of C-Type Lectin REG3α and Gut Damage in People With Human Immunodeficiency Virus

(2019) Stéphane Isnard et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of Hiv-Related Gut Microbiota Alterations on Metabolic Comorbidities

(2019) Marco Gelpi et al.   CLINICAL INFECTIOUS DISEASES

Suboptimal immune recovery during antiretroviral therapy with sustained HIV suppression in sub-Saharan Africa

(2018) Stefanie Kroeze et al.   AIDS

Incomplete Recovery of CD4 Cell Count, CD4 Percentage, and CD4/CD8 Ratio in Patients With Human Immunodeficiency Virus Infection and Suppressed Viremia During Long-term Antiretroviral Therapy

(2018) Yoshikazu Mutoh et al.   CLINICAL INFECTIOUS DISEASES

Higher Levels of Peripheral Th17 T CD4+ Cells Are Associated With Immunological Non Response in HIV-Infected Patients Under Effective ART

(2018) Ilaria De Benedetto et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Intestinal damage precedes mucosal immune dysfunction in SIV infection

(2018) Tiffany Hensley-McBain et al.   Mucosal Immunology

Impact of antiretroviral drugs on the microbiome

(2018) Sandra Pinto-Cardoso et al.   Current Opinion in HIV and AIDS

Association Between Gut Microbiota and CD4 Recovery in HIV-1 Infected Patients

(2018) Wei Lu et al.   Frontiers in Microbiology

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals

(2018) Soo Ching Lee et al.   Scientific Reports

CD4 cell count recovery after combined antiretroviral therapy in the modern cART era

(2018) Hélène Roul et al.   AIDS

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

(2016) Josué Pérez-Santiago et al.   AIDS

Impaired gut junctional complexes feature late-treated individuals with suboptimal CD4+ T-cell recovery upon virologically suppressive combination antiretroviral therapy

(2016) Camilla Tincati et al.   AIDS

Immunologic profiles distinguish aviremic HIV-infected adults

(2016) Christina M. Ramirez et al.   AIDS

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

(2016) Cynthia L. Monaco et al.   Cell Host & Microbe

Increase in frequencies of circulating Th-17 cells correlates with microbial translocation, immune activation and exhaustion in HIV-1 infected patients with poor CD4 T-cell reconstitution

(2016) Ranjini Valiathan et al.   IMMUNOBIOLOGY

Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts

(2016) Birgitte Stiksrud et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression

(2016) Joseph C. Mudd et al.   JOURNAL OF INFECTIOUS DISEASES

Discordant Immune Response with Antiretroviral Therapy in HIV-1: A Systematic Review of Clinical Outcomes

(2016) Christine Kelly et al.   PLoS One

Gut Microbiota Linked to Sexual Preference and HIV Infection

(2016) Marc Noguera-Julian et al.   EBioMedicine

Gut epithelial barrier and systemic inflammation during chronic HIV infection

(2015) Ma Somsouk et al.   AIDS

Analysis of Th17 and Tc17 Frequencies and Antiviral Defenses in Gut-Associated Lymphoid Tissue of Chronic HIV-1 Positive Patients

(2015) Gabriella d’Ettorre et al.   MEDIATORS OF INFLAMMATION

Soluble Markers of Inflammation and Coagulation but Not T-Cell Activation Predict Non–AIDS-Defining Morbid Events During Suppressive Antiretroviral Treatment

(2014) Allan R. Tenorio et al.   JOURNAL OF INFECTIOUS DISEASES

Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

(2014) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES

Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

(2014) A Kök et al.   Mucosal Immunology

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

(2014) Alexandra Schuetz et al.   PLoS Pathogens

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

(2014) Sergio Serrano-Villar et al.   PLoS Pathogens

Immunodiscordant responses to HAART – mechanisms and consequences

(2013) Marta Massanella et al.   Expert Review of Clinical Immunology

Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

(2013) Ivan Vujkovic-Cvijin et al.   Science Translational Medicine

Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment

(2012) Giuseppe Lapadula et al.   AIDS

Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?

(2012) C T Costiniuk et al.   Mucosal Immunology

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection

(2012) N R Klatt et al.   Mucosal Immunology

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

(2012) C J Kim et al.   Mucosal Immunology

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

(2011) Damalie Nakanjako et al.   BMC INFECTIOUS DISEASES

Immunologic Failure Despite Suppressive Antiretroviral Therapy Is Related to Activation and Turnover of Memory CD4 Cells

(2011) Michael M. Lederman et al.   JOURNAL OF INFECTIOUS DISEASES

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Immune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy

(2010) Stefania Piconi et al.   AIDS

Low CD4+T Cell Count Is a Risk Factor for Cardiovascular Disease Events in the HIV Outpatient Study

(2010) Kenneth A. Lichtenstein et al.   CLINICAL INFECTIOUS DISEASES

Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy

(2008) Giulia Marchetti et al.   AIDS