A Systems View of the Heparan Sulfate Interactome

Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein

(2020) Daniel R. Sandoval et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

(2020) Zehra Elgundi et al.   Frontiers in Oncology

Receptor tyrosine kinases and heparan sulfate proteoglycans: Interplay providing anticancer targeting strategies and new therapeutic opportunities

(2020) Cinzia Lanzi et al.   BIOCHEMICAL PHARMACOLOGY

Receptor Tyrosine Kinase-Targeted Cancer Therapy

(2018) Toshimitsu Yamaoka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Heparan Sulfate Microarray Reveals That Heparan Sulfate–Protein Binding Exhibits Different Ligand Requirements

(2017) Chengli Zong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural similarities in the CPC clip motif explain peptide-binding promiscuity between glycosaminoglycans and lipopolysaccharides

(2017) David Pulido et al.   Journal of the Royal Society Interface

Expanding the 3-O-Sulfate Proteome—Enhanced Binding of Neuropilin-1 to 3-O-Sulfated Heparan Sulfate Modulates Its Activity

(2016) Bryan E. Thacker et al.   ACS Chemical Biology

Extension and validation of the GLYCAM force field parameters for modeling glycosaminoglycans

(2016) Arunima Singh et al.   CANADIAN JOURNAL OF CHEMISTRY

Exploring the glycosaminoglycan-protein interaction network by glycan-mediated pull-down proteomics

(2016) Bernd Gesslbauer et al.   ELECTROPHORESIS

Estimating glycosaminoglycan–protein interaction affinity: water dominates the specific antithrombin–heparin interaction

(2016) Aurijit Sarkar et al.   GLYCOBIOLOGY

Computational analysis of interactions in structurally available protein–glycosaminoglycan complexes

(2016) Sergey A Samsonov et al.   GLYCOBIOLOGY

Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism

(2016) Hudie Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cellsin Vitro

(2016) Markus A. Loeven et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries

(2016) Christopher M. Allan et al.   JOURNAL OF LIPID RESEARCH

Proteomic analysis of egg white heparin-binding proteins: towards the identification of natural antibacterial molecules

(2016) Nicolas Guyot et al.   Scientific Reports

Systematic protein interactome analysis of glycosaminoglycans revealed YcbS as a novel bacterial virulence factor

(2016) Felix Shih-Hsiang Hsiao et al.   Scientific Reports

Re-visiting the structure of heparin

(2015) Benito Casu et al.   CARBOHYDRATE RESEARCH

Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels

(2015) Sandeep Gopal et al.   JOURNAL OF CELL BIOLOGY

The role of heparan sulfate as determining pathogenic factor in complement factor H-associated diseases

(2015) Markus A. Loeven et al.   MOLECULAR IMMUNOLOGY

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins

(2014) Nehru Viji Sankaranarayanan et al.   GLYCOBIOLOGY

Docking Server for the Identification of Heparin Binding Sites on Proteins

(2014) Scott E. Mottarella et al.   Journal of Chemical Information and Modeling

A comparative study on the heparin-binding proteomes ofToxoplasma gondiiandPlasmodium falciparum

(2014) Yan Zhang et al.   PROTEOMICS

Affinity chromatography, two-dimensional electrophoresis, adapted immunodepletion and mass spectrometry used for detection of porcine and piscine heparin-binding human plasma proteins

(2013) Stefanía Guðrún Bjarnadóttir et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

(2013) Jon C. Gonzales et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic Analysis of Plasmodium falciparum Schizonts Reveals Heparin-Binding Merozoite Proteins

(2013) Yan Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Exploring mechanisms of FGF signalling through the lens of structural biology

(2013) Regina Goetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasmodium rhoptry proteins: why order is important

(2013) Natalie A. Counihan et al.   TRENDS IN PARASITOLOGY

The “CPC Clip Motif”: A Conserved Structural Signature for Heparin-Binding Proteins

(2012) Marc Torrent et al.   PLoS One

An unexpected link between angiotensinogen and thrombin

(2011) Yunjie Wang et al.   FEBS LETTERS

Heparan Sulfate Is Essential for High Mobility Group Protein 1 (HMGB1) Signaling by the Receptor for Advanced Glycation End Products (RAGE)

(2011) Ding Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome

(2011) Alessandro Ori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docking glycosaminoglycans to proteins: analysis of solvent inclusion

(2011) Sergey A. Samsonov et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-Related Macular Degeneration

(2010) U. Kelly et al.   JOURNAL OF IMMUNOLOGY

Deletion of the Basement Membrane Heparan Sulfate Proteoglycan Type XVIII Collagen Causes Hypertriglyceridemia in Mice and Humans

(2010) Joseph R. Bishop et al.   PLoS One

Free energy calculations of glycosaminoglycan–protein interactions

(2009) Neha S Gandhi et al.   GLYCOBIOLOGY

Mutations of Factor H Impair Regulation of Surface-bound C3b by Three Mechanisms in Atypical Hemolytic Uremic Syndrome

(2009) Markus J. Lehtinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development

(2009) Z. Hu et al.   JOURNAL OF CELL SCIENCE

Identification of Heparin-binding Sites in Proteins by Selective Labeling

(2009) Alessandro Ori et al.   MOLECULAR & CELLULAR PROTEOMICS

Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan

(2008) Maria Ringvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Heparin-binding proteins of human seminal plasma: purification and characterization

(2008) Vijay Kumar et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT