Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels

Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes

(2014) Thomas Thestrup et al.   NATURE METHODS

The wound healing, chronic fibrosis, and cancer progression triad

(2014) Brad Rybinski et al.   PHYSIOLOGICAL GENOMICS

Syndecans as Modulators and Potential Pharmacological Targets in Cancer Progression

(2014) Despoina Barbouri et al.   Frontiers in Oncology

TRPC4 Inactivation Confers a Survival Benefit in Severe Pulmonary Arterial Hypertension

(2013) Abdallah Alzoubi et al.   AMERICAN JOURNAL OF PATHOLOGY

Syndecan-4 Phosphorylation Is a Control Point for Integrin Recycling

(2013) Mark R. Morgan et al.   DEVELOPMENTAL CELL

The heparanase/syndecan-1 axis in cancer: mechanisms and therapies

(2013) Vishnu C. Ramani et al.   FEBS Journal

A Chemoreceptor That Detects Molecular Carbon Dioxide

(2013) Ewan St. John Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mediators for Raft-dependent Endocytosis of Syndecan-1, a Highly Conserved, Multifunctional Receptor

(2013) Keyang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Epidermal MicroRNA Regulates Neuronal Migration Through Control of the Cellular Glycosylation State

(2013) M. E. Pedersen et al.   SCIENCE

Distinct 3- O -Sulfated Heparan Sulfate Modification Patterns Are Required for kal-1 −Dependent Neurite Branching in a Context-Dependent Manner in Caenorhabditis elegans

(2013) Eillen Tecle et al.   G3-Genes Genomes Genetics

A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo

(2012) Jennifer Davis et al.   DEVELOPMENTAL CELL

Alpha-actinin interactions with syndecan-4 are integral to fibroblast–matrix adhesion and regulate cytoskeletal architecture

(2012) E. Okina et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Plasma membrane ion fluxes and NFAT-dependent gene transcription contribute to c-met-induced epithelial scattering

(2012) Peter R. Langford et al.   JOURNAL OF CELL SCIENCE

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Syndecans in cartilage breakdown and synovial inflammation

(2012) Thomas Pap et al.   Nature Reviews Rheumatology

Syndecan-4 signalling inhibits apoptosis and controls NFAT activity during myocardial damage and remodelling

(2011) Frank Echtermeyer et al.   CARDIOVASCULAR RESEARCH

A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis

(2011) Mark D. Bass et al.   DEVELOPMENTAL CELL

Syndecan-1 and Syndecan-4 Are Independent Indicators in Breast Carcinoma

(2011) Maria E. Lendorf et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

(2011) Masha Prager-Khoutorsky et al.   NATURE CELL BIOLOGY

Reduced TRPC Channel Expression in Psoriatic Keratinocytes Is Associated with Impaired Differentiation and Enhanced Proliferation

(2011) Kristina Leuner et al.   PLoS One

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway

(2011) Alexandra V. Finsen et al.   PLoS One

Transmembrane Signaling Proteoglycans

(2010) John R. Couchman   Annual Review of Cell and Developmental Biology

Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion

(2010) Sandeep Gopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neighborly relations: cadherins and mechanotransduction: Figure 1.

(2010) Michael Smutny et al.   JOURNAL OF CELL BIOLOGY

Chemotaxis of MDCK-F cells toward fibroblast growth factor-2 depends on transient receptor potential canonical channel 1

(2010) Anke Fabian et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

SDN-1/syndecan regulates growth factor signaling in distal tip cell migrations in C. elegans

(2009) Megan Schwabiuk et al.   DEVELOPMENTAL BIOLOGY

Function and regulation of TRP family channels in C. elegans

(2009) Rui Xiao et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators

(2009) S. Martinez-Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin stress fibers transmit and focus force to activate mechanosensitive channels

(2008) Kimihide Hayakawa et al.   JOURNAL OF CELL SCIENCE

TRPC channels determine human keratinocyte differentiation: New insight into basal cell carcinoma

(2007) Benjamin Beck et al.   CELL CALCIUM