Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma

Guidelines and definitions for research on epithelial–mesenchymal transition

(2020) Jing Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial–Mesenchymal Transition Programs and Cancer Stem Cell Phenotypes: Mediators of Breast Cancer Therapy Resistance

(2020) Alex J. Gooding et al.   MOLECULAR CANCER RESEARCH

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

(2020) Jesus M. Banales et al.   Nature Reviews Gastroenterology & Hepatology

Cholangiocarcinoma: Epidemiology and risk factors

(2019) Shahid A. Khan et al.   LIVER INTERNATIONAL

Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma

(2019) Silvestre Vicent et al.   LIVER INTERNATIONAL

Reply to: “Global trends in mortality from intrahepatic and extrahepatic cholangiocarcinoma”

(2019) Paola Bertuccio et al.   JOURNAL OF HEPATOLOGY

Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro

(2019) Lorenzo Nevi et al.   Cells

Hepatic peroxisome proliferator-activated receptor γ coactivator 1β drives mitochondrial and anabolic signatures that contribute to hepatocellular carcinoma progression in mice

(2018) Elena Piccinin et al.   HEPATOLOGY

PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect

(2018) Dan Li et al.   Cell Death & Disease

Neoplastic transformation of peribiliary stem cell niche in cholangiocarcinoma arisen in primary sclerosing cholangitis

(2018) Guido Carpino et al.   HEPATOLOGY

Stromal-induced downregulation of miR-1247 promotes prostate cancer malignancy

(2018) Maria Letizia Taddei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia

(2017) Alessandra Carcereri de Prati et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages

(2017) Chiara Raggi et al.   JOURNAL OF HEPATOLOGY

Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells

(2017) Chiara Raggi et al.   Scientific Reports

TUFM downregulation induces epithelial–mesenchymal transition and invasion in lung cancer cells via a mechanism involving AMPK-GSK3β signaling

(2016) Kai He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cancer Stem cells and their cellular origins in primary liver and biliary tract cancers

(2016) Tsunekazu Oikawa   HEPATOLOGY

Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

(2016) Jesus M. Banales et al.   Nature Reviews Gastroenterology & Hepatology

SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis

(2016) Yuming Li et al.   Oncotarget

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

(2016) Luigi Ippolito et al.   Oncotarget

Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancer

(2016) Margherita Correnti et al.   Oncotarget

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells

(2015) Patricia Sancho et al.   Cell Metabolism

Impact of microenvironment and stem-like plasticity in cholangiocarcinoma: Molecular networks and biological concepts

(2015) Chiara Raggi et al.   JOURNAL OF HEPATOLOGY

Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies

(2015) C Raggi et al.   ONCOGENE

Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells

(2015) Arianna De Luca et al.   Oncotarget

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

(2015) Rebecca Lamb et al.   Oncotarget

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

(2015) Anna Pastò et al.   Oncotarget

Metabolic differences in breast cancer stem cells and differentiated progeny

(2014) Erina Vlashi et al.   BREAST CANCER RESEARCH AND TREATMENT

Epigenetic reprogramming modulates malignant properties of human liver cancer

(2014) Chiara Raggi et al.   HEPATOLOGY

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

(2013) Florian A. Siebzehnrubl et al.   EMBO Molecular Medicine

Cutting Edge: Hypoxia-Induced Nanog Favors the Intratumoral Infiltration of Regulatory T Cells and Macrophages via Direct Regulation of TGF- 1

(2013) M. Hasmim et al.   JOURNAL OF IMMUNOLOGY

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

(2013) William A Flavahan et al.   NATURE NEUROSCIENCE

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

(2012) M. Janiszewska et al.   GENES & DEVELOPMENT

Discrete nature of EpCAM+and CD90+cancer stem cells in human hepatocellular carcinoma

(2012) Taro Yamashita et al.   HEPATOLOGY

Therapeutic targets in cancer cell metabolism and autophagy

(2012) Heesun Cheong et al.   NATURE BIOTECHNOLOGY

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

(2012) S. J. Conley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways

(2011) Jens U. Marquardt et al.   HEPATOLOGY

AMP-activated protein kinase is required for induction of apoptosis and epithelial-to-mesenchymal transition

(2010) Xunde Wang et al.   CELLULAR SIGNALLING

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY