Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia

The antineoplastic agent α-bisabolol promotes cell death by inducing pores in mitochondria and lysosomes

(2016) Antonella Rigo et al.   APOPTOSIS

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

(2015) Laura Poillet-Perez et al.   Redox Biology

Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

(2015) Hyunsook An et al.   PLoS One

Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability

(2014) Rohann J.M. Correa et al.   CARCINOGENESIS

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

(2014) Carsten Wenzel et al.   EXPERIMENTAL CELL RESEARCH

Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia

(2014) Hiroko Endo et al.   PLoS One

Epithelial-to-Mesenchymal Transition Activates PERK-eIF2  and Sensitizes Cells to Endoplasmic Reticulum Stress

(2014) Y.-x. Feng et al.   Cancer Discovery

Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs

(2013) Elena Butturini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metastasis Awakening: Targeting dormant cancer

(2013) Julio A Aguirre-Ghiso et al.   NATURE MEDICINE

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

(2012) Lin Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Clinical opportunities and challenges in targeting tumour dormancy

(2012) Jonathan A. Hensel et al.   Nature Reviews Clinical Oncology

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers

(2011) Kate Lawrenson et al.   CARCINOGENESIS

Modulation of AKT activity is associated with reversible dormancy in ascites-derived epithelial ovarian cancer spheroids

(2011) Rohann J. M. Correa et al.   CARCINOGENESIS

Two Naturally Occurring Terpenes, Dehydrocostuslactone and Costunolide, Decrease Intracellular GSH Content and Inhibit STAT3 Activation

(2011) Elena Butturini et al.   PLoS One

Computational Identification of a p38SAPK-Regulated Transcription Factor Network Required for Tumor Cell Quiescence

(2009) A. P. Adam et al.   CANCER RESEARCH

The late stages of autophagy: how does the end begin?

(2009) T Noda et al.   CELL DEATH AND DIFFERENTIATION

The breast cancer cells response to chronic hypoxia involves the opposite regulation of NF-kB and estrogen receptor signaling

(2009) Alexander M. Scherbakov et al.   STEROIDS

OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species-Related Autophagy in Hepatocellular Carcinoma

(2008) M. Gao et al.   CANCER RESEARCH

Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype

(2008) Katharine L. Sodek et al.   INTERNATIONAL JOURNAL OF CANCER

Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids

(2008) Dario Barbone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis

(2008) María Valcárcel et al.   Journal of Translational Medicine